500 Results for "

CD3

" in MedChemExpress (MCE) Product Catalog:
Products (500)

500 Results for "CD3" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-12715S
CAS No.: 1261254-59-4
Purity:  ≥99.0%
Yohimbine- 13C,d3 is the 13C- and deuterium labeled Yohimbine. Yohimbine is a potent and relatively nonselective alpha 2-adrenergic receptor (AR) antagonist, with IC50 of 0.6 μM.
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1
1 Cited Publications
Cat. No.: HY-10201S2
CAS No.: 1210608-86-8
Purity:  98.35%
Synonyms: Bay 43-9006-13C,d3
Sorafenib- 13C,d3 (Bay 43-9006- 13C,d3) is the 13C, deuterated-labeled Sorafenib (HY-10201). Sorafenib (Bay 43-9006) is a potent oral active multikinase inhibitor. Sorafenib blocks autophosphorylation and activity of receptor tyrosine kinases (VEGFR-2, VEGFR-3) and RAF family kinases, thereby suppressing the RAF/MEK/ERK and PI3K/Akt pathways, inhibiting STAT3 phosphorylation, and selectively inhibiting the MAPK pathway in cancer cells. Sorafenib induces cell cycle arrest, autophagy, apoptosis, and PARP cleavage, reduces Bcl-2, Bcl-XL, cyclin D1 levels, and activates Bak and Bax. Sorafenib inhibits tumor growth and metastasis in mouse and rat models. Sorafenib can be used for cancer research, such as colon, breast, non-small-cell lung cancer (NSCLC), ovarian, pancreatic, melanoma, colorectal and hepatocellular carcinoma [3] .
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Cat. No.: HY-P99392
CAS No.: 2119595-80-9
Synonyms: JNJ-7957; JNJ-64007957; Tecvayli

Target:  

CD3

Research Areas:  

Cancer

Teclistamab is a human bispecific antibody to BCMA and CD3 that recognizes BCMA on target cells and CD3 on T cells and induces T cell-mediated cytotoxicity leading to T cell activation and subsequent target cell lysis. Teclistamab can be used in studies of diseases related to multiple myeloma (MM) .
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Cat. No.: HY-P990864

Target:  

CD3

Research Areas:  

Inflammation/Immunology

Anti-CD3 Antibody (OKT-3) is a kind of mouse IgG2a κ antibody inhibitor, targeting to human CD3. Anti-CD3 Antibody (OKT-3) decreases T cells. Anti-CD3 Antibody (OKT-3) can be used for the research of immunology, such as graft-versus-host disease [3].
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Cat. No.: HY-P99539
CAS No.: 2305629-50-7
Synonyms: REGN4018

Target:  

CD3

Research Areas:  

Cancer

Ubamatamab (REGN4018) is a humanized bispecific antibody targeted against Mucin 16 (MUC16) and CD3. Ubamatamab demonstrates potent antitumor activity .
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Cat. No.: HY-P99038
CAS No.: 1801338-64-6
Synonyms: REGN1979

Target:  

CD20 CD3

Research Areas:  

Cancer

Odronextamab is a stable humanized IgG4 CD20 × CD3 bispecific antibody that binds to CD3 on T cells and CD20 on B cells, triggering anti-tumor activity. Odronextamab is expected to be used in oncology research .
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Cat. No.: HY-P99152
CAS No.: 140608-64-6
Synonyms: Muromanab-CD3

Research Areas:  

Inflammation/Immunology Cancer

Muromonab (Muromonab-CD3; OKT3) is a mouse monoclonal antibody targeting the CD3 antigen. Muromonab specifically binds to the CD3 antigen on the surface of human and higher primate T cells. Muromonab blocks the function of T cell receptors to recognize foreign antigens and inhibits T cell-mediated immune responses, including cell-mediated lymphocyte lysis and T cell proliferation responses. Muromonab can be used to study acute kidney, liver, heart and combined kidney-pancreas transplant rejection, and can also be used to study graft-versus-host disease in bone marrow transplant patients [3] .
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Cat. No.: HY-P99332
CAS No.: 219716-33-3
Synonyms: Anti-Human CD3E Recombinant Antibody; HuM291

Target:  

Apoptosis

Research Areas:  

Inflammation/Immunology Cancer

Visilizumab (Anti-Human CD3E Recombinant Antibody) is a humanized low-Fc receptor binding anti-CD3 monoclonal IgG2 antibody. Visilizumab can be used for ulcerative colitis and Crohn's disease research .
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Cat. No.: HY-P990925
CAS No.: 2885203-43-8
Synonyms: BLYG8824A; RG6286
Target:  

CD3

Research Areas:  

Inflammation/Immunology

Linclatamig (BLYG8824A) is a humanized IgG1 T-cell engaging bispecific antibody (TCB) targeting LY6G6D and CD3. Linclatamig can bind to LY6G6D and CD3-positive T cells, forming an immunological synapse to promote T cell-mediated killing of LY6G6D-positive cells. Linclatamig can be used in colorectal cancer research .
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Cat. No.: HY-P99523
CAS No.: 2413453-53-7
Synonyms: AMG 199

Target:  

CD3

Research Areas:  

Cancer

Vepsitamab (AMG 199) is a bispecific T-cell engager (HLE BiTE) that binds to MUC17 and CD3. Vepsitamab directs CD3-positive cells to target MUC17-positive cells. Vepsitamab induces cell activation and proliferation. Vepsitamab is applicable to research related to gastric cancer and gastroesophageal junction (g/gej) cancer .
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Cat. No.: HY-P99211
CAS No.: 881191-44-2
Synonyms: ChAglyCD3; TRX 4

Target:  

CD3

Research Areas:  

Metabolic Disease

Otelixizumab (ChAglyCD3) is an anti-human CD3 monoclonal antibody and can be used for the research of type 1 diabetes .
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Cat. No.: HY-P990730
CAS No.: 2755301-09-6
Synonyms: ARB202

Target:  

CD3 Cadherin

Research Areas:  

Cancer

Cabotamig is a humanized bispecific T-cell engager antibody targeting CDH17/CD3. Cabotamig is generated from anti-CDH17 monoclonal ARB102 by linking a CD3-binding scFv in the format of IgG4-scFv. Cabotamig can be used for the research of cancer, such as gastric cancer and colon cancers .
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Cat. No.: HY-P991163
CAS No.: 2969220-04-8

Target:  

CD3 Claudin

Research Areas:  

Cancer

Tixentamig is a bispecific monoclonal antibody targeting human CD3 ε and CLDN18 (claudin 18). Tixentamig is promising for research of cancers .
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Cat. No.: HY-P991842
Anti-CD3 Antibody (UCHT-1) is an antibody targeting CD3. Anti-CD3 Antibody (UCHT-1) activates the phospholipase C and phosphatidylinositol 3-kinase (PI3K) signaling pathways, elevates intracellular calcium levels, regulates the T3 epitope, and triggers T lymphocyte proliferation. Anti-CD3 Antibody (UCHT-1) also inhibits lymphocyte proliferation, abolishes IL-2 production, and blocks the expression of IL-2 receptors. Anti-CD3 Antibody (UCHT-1) is applicable to research related to graft-versus-host disease, acute myeloid leukemia, and B-cell acute lymphoblastic leukemia [3] .
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Cat. No.: HY-P99837
CAS No.: 2367001-71-4
Synonyms: SPV-T3a

Target:  

CD3

Research Areas:  

Infection

Dafsolimab (SPV-T3a) is a Mouse IgG2b monoclonal antibody (anti-CD3). Dafsolimab can induce cell death through modulation and activation of the CD3/T cell receptor complex. Dafsolimab can be used for the research of graft-versus-host disease (GVHD) .
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Cat. No.: HY-K0356

MCE Human CD3 Cell Depletion Magnetic Beads (Positive Selection) are magnetic beads covalently coupled with anti-human CD3 antibodies, enabling the specific binding and magnetic removal of CD3+ cells from single-cell suspensions derived from human peripheral blood mononuclear cells (PBMCs) or human peripheral blood leukocytes (WBCs). This allows efficient enrichment of the non-CD3+ cell population.

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Cat. No.: HY-K0355

MCE Mouse CD3 Cell Depletion Magnetic Beads (Positive Selection) are magnetic beads covalently coupled with anti-mouse CD3 antibodies, enabling the specific binding and magnetic removal of CD3+ cells from single-cell suspensions derived from mouse spleen and other tissues. This allows efficient enrichment of the non-CD3+ cell population.

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Cat. No.: HY-RS02243
Research Areas:  

Others

CD3E Human Pre-designed siRNA Set A contains three designed siRNAs for CD3E gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS02242
Research Areas:  

Others

CD3D Human Pre-designed siRNA Set A contains three designed siRNAs for CD3D gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS02244
Research Areas:  

Others

CD3G Human Pre-designed siRNA Set A contains three designed siRNAs for CD3G gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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