173 Results for "

Target ability

" in MedChemExpress (MCE) Product Catalog:
Products (173)

173 Results for "Target ability" in MCE Product Catalog:

Cat. No.: HY-P10501A
Target:  

Antifolate

Research Areas:  

Cancer

FRα-targeting peptide C7 TFA is a selective peptide ligand for folate receptor α (FRα) that has specific binding to FRα expressing cells and in vivo tumor targeting ability. FRα-targeting peptide C7 TFA can be used in the research of tumor diagnosis and treatment .
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Cat. No.: HY-132260
CAS No.: 1607824-64-5
Synonyms: IMGN529; Debio 1562

Research Areas:  

Cancer

Naratuximab emtansine (IMGN529) is a CD37-targeted ADC consisting of a humanized IgG1 mAb coupled to the microtubule disruptor DM1. Naratuximab emtansine has high affinity and specificity for CD37, allowing ADC internalization, processing and intracellular release of DM1. Due to its ability to disrupt microtubule assembly, DM1 can subsequently induce cell cycle arrest and apoptosis .
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Cat. No.: HY-W008003
CAS No.: 615-16-7
2-Hydroxybenzimidazole is an inactive compound targeting CYP1A1 and is mainly used as a control compound in the structure-activity relationship study of benzimidazole derivatives. 2-Hydroxybenzimidazole does not have the ability to induce CYP1A1 expression like its thiol or amino substituted derivatives .
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Cat. No.: HY-W873634
CAS No.: 1242003-07-1
Synonyms: TRAP-Pr
Research Areas:  

Cancer

TRAP-Pr is a radionuclide conjugate (RDC) that can bind to the radionuclide [68]Ga. RDCs have the ability to specifically target biomolecules and can be used in medical imaging or therapy. TRAP-Pr can be further functionalized with acetone and used in click chemistry CuAAC reactions to conjugate other labeled molecules.
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Cat. No.: HY-157512
CAS No.: 2413035-43-3
Target:  

Ligands for E3 Ligase

Research Areas:  

Cancer

SJF-0661 is a variant of the von Hippel-Lindau (VHL) protein ligand with no targeted degradation ability and can be used as a control reagent for the VHL ubiquitin ligase ligand. SJF-0661 is a variant obtained by inverting the stereocenter of the key hydroxyproline group in the VHL ligand .
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Cat. No.: HY-W011118
CAS No.: 23911-26-4
Research Areas:  

Cancer

DTPA anhydride is a bifunctional chelator whose anhydride can react with amino groups in proteins (such as lysine residues) to form stable amide bonds. DTPA anhydride can also bind to radionuclides to synthesize radionuclide-labeled drug conjugates (RDCs). RDCs have the ability to specifically target biomolecules and can be used in medical imaging or therapy.
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Cat. No.: HY-178489
Target:  

Nectin-4

Research Areas:  

Cancer

BGC1614 is a Nectin-4-targeting bicyclic toxin conjugate (BTC) belonging to the category of peptide-drug conjugates (PDCs). BGC1614 exhibits strong targeted binding ability to Nectin-4, with an KD of 3.859 × 10 -7 M. BGC1614 exhibits superior antitumor efficacy in nude mice bearing PC-3 and N87 tumor xenografts. BGC1614 can be used for research related to Nectin-4-overexpressing tumors (such as prostate cancer, gastric cancer) .
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Cat. No.: HY-164653
CAS No.: 137076-50-7
Research Areas:  

Cancer

DOTAEt is a radionuclide conjugate (RDC), which is capable of binding to a radionuclide. RDC has the ability to specifically target biomolecules and can be used in medical imaging or therapy .
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Cat. No.: HY-164590
CAS No.: 2256055-98-6
Research Areas:  

Cancer

BCN-NODAGA is a radionuclide conjugate (RDC), which is capable of binding to a radionuclide. RDC has the ability to specifically target biomolecules and can be used in medical imaging or therapy .
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Cat. No.: HY-P10730
CAS No.: 213187-44-1
Research Areas:  

Cancer

DOTA-Lanreotide is a radionuclide conjugate (RDC), which is capable of binding to a radionuclide. RDC has the ability to specifically target biomolecules and can be used in medical imaging or therapy .
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Cat. No.: HY-164594
Research Areas:  

Cancer

TA-DOTA-GA is a radionuclide conjugate (RDC), which is capable of binding to a radionuclide. RDC has the ability to specifically target biomolecules and can be used in medical imaging or therapy .
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Cat. No.: HY-P10501
CAS No.: 2159055-74-8
Target:  

Antifolate

Research Areas:  

Cancer

FRα-targeting peptide C7 is a selective peptide ligand for folate receptor α (FRα) that has specific binding to FRα expressing cells and in vivo tumor targeting ability. FRα-targeting peptide C7 can be used in the research of tumor diagnosis and treatment .
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Cat. No.: HY-177921
CAS No.: 3058580-71-2
Target:  

Liposome

Research Areas:  

Others

PL53 is a kind of cycloalkylamine lipid nanoparticles. PL53 exhibits outstanding transfection efficiency both in vitro and in vivo, especially showing strong protein expression ability and potential tissue targeting after intramuscular injection. PL53 can be used for the study of nucleic acid delivery .
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Cat. No.: HY-113011R
CAS No.: 1109-28-0
Maltotriose (Standard) is the analytical standard of Maltotriose (HY-13011). This product is intended for research and analytical applications. Maltotriose is a maltooligosaccharide and a specific inducer of the Escherichia coli maltose operon. The oligosaccharide structure of Maltotriose acts as a highly efficient drug delivery carrier, which significantly enhances the targeting ability and water solubility of photosensitizers in photodynamic therapy for pancreatic cancer.
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Cat. No.: HY-151207
CAS No.: 2820286-56-2
Target:  

Apoptosis ADC Payloads

Research Areas:  

Cancer

Anticancer agent 81 (Compound 37b3) is an anticancer agent and can induce tumor cell cycle arrest and apoptosis. Anticancer agent 81 can be used as a payload to conjugate with Trastuzumab (HY-P9907) to obtain the antibody–agent conjugate (ADC) T-PBA. T-PBA maintained its mode of target and internalization ability of Trastuzumab .
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Cat. No.: HY-169208
CAS No.: 3036376-10-7
Target:  

TAM Receptor

Research Areas:  

Cancer

MerTK-IN-1 (compund 31) is a MerTK inhibitor with in vivo target binding ability .
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Cat. No.: HY-164589
CAS No.: 1397275-76-1
Research Areas:  

Cancer

NOPO is a radionuclide conjugate (RDC), which is capable of binding to a radionuclide. RDC has the ability to specifically target biomolecules and can be used in medical imaging or therapy .
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Cat. No.: HY-164599
CAS No.: 2451069-30-8
Research Areas:  

Cancer

TA-DOTA is a radionuclide conjugate (RDC), which is capable of binding to a radionuclide. RDC has the ability to specifically target biomolecules and can be used in medical imaging or therapy .
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Cat. No.: HY-P10731
CAS No.: 935886-72-9
Research Areas:  

Cancer

DOTA-NAPamide is a radionuclide conjugate (RDC), which is capable of binding to a radionuclide. RDC has the ability to specifically target biomolecules and can be used in medical imaging or therapy .
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Cat. No.: HY-164592
CAS No.: 180152-83-4
Research Areas:  

Cancer

DTPA-tetra(tBu)ester is a radionuclide conjugate (RDC), which is capable of binding to a radionuclide. RDC has the ability to specifically target biomolecules and can be used in medical imaging or therapy .
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