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Cat. No.: HY-169208

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MerTK-IN-1

MerTK-IN-1 (compund 31) is a MerTK inhibitor with in vivo target binding ability.

For research use only. We do not sell to patients.

CAS No.: 3036376-10-7
Formula: C₂₃H₂₆N₈O₄
Molecular Weight:478.50

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (265 KB)

MerTK-IN-1 Chemical Structure

CAS No.: 3036376-10-7

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Bioz

Biological Activity

Description

MerTK-IN-1 (compund 31) is a MerTK inhibitor with in vivo target binding ability^[1].

IC₅₀ & Target

MerTK^[1]

All TAM Receptor Isoforms :

Chemical Information

CAS No. 3036376-10-7
Molecular Weight 478.50
Formula C₂₃H₂₆N₈O₄
SMILES

NC(C1=C(N=CC(C2CN(C2)C3=NC4=C(O3)C=C(OCC(C)(O)C)C=C4)=N1)NC5=CN(N=C5)C)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (265 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Frey RR, et al. Discovery of Potent Azetidine-Benzoxazole MerTK Inhibitors with In Vivo Target Engagement. J Med Chem. 2024 Oct 10;67(19):17033-17052. [Content Brief]

Calculators

Molarity Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Dilution Calculator

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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