Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
131 Results for "
complex-1
" in MedChemExpress (MCE) Product Catalog:
Products (131)
131 Results for "complex-1" in MCE Product Catalog:
Target:
Research Areas:
RB-3, a polycomb repressive complex 1 (PRC1) inhibitor, binds to RING1B-BMI1f, with a Kd of 2.8 μM [1].
Target:
Research Areas:
Gentamicin C1a is the precursor of the semi-synthetic antibiotic Etimicin, and has antibacterial activity. Gentamicin C1a is the major component of the Gentamicin complex .
Cat. No.: HY-164027
CAS No.: 2614161-13-4
Target:
Research Areas:
MyoMed 205 is an orally active muscle ring finger protein 1 (MuRF1) inhibitor. MyoMed-205 reduces ubiquitination and subsequent proteasomal degradation of muscle proteins by inhibiting MuRF1 activity. MyoMed 205 augments muscle performance, attenuates muscle weight loss and alleviates disease-induced weight loss. MyoMed 205 can be used for the research of cancer cachexia, type 2 diabetes mellitus, and heart failure with preserved ejection fraction [1] .
Cat. No.: HY-P99322
CAS No.: 1531594-08-7
Synonyms: LFG316; Anti-Human C5 Recombinant Antibody
Target:
Research Areas:
Cat. No.: HY-W015302
CAS No.: 88-21-1
Synonyms: Orthanilic acid; 2-Aminobenzenesulphonic acid
Target:
Cat. No.: HY-W021022
CAS No.: 14996-61-3
Synonyms: Iridium trichloride hydrate
Target:
Research Areas:
UCB-5307 is a potent TNF signaling inhibitor with a KD of 9 nM for human TNFα. UCB-5307 can penetrate the preformed hTNF/hTNFR1 complex .
YK5 is a potent and selective Hsp70 inhibitor. YK5 selectively and tightly binds to the cytosolic Hsp70s in cancer cells. YK5 has biological activity partly by interfering with the formation of active oncogenic Hsp70/Hsp90/client protein complexes .
Cat. No.: HY-15777R
CAS No.: 1211441-98-3
Synonyms: LEE011 (Standard)
Target:
Research Areas:
Ribociclib (Standard) is the analytical standard of Ribociclib. This product is intended for research and analytical applications. Ribociclib (LEE01) is a highly specific CDK4/6 inhibitor with IC50 values of 10 nM and 39 nM, respectively, and is over 1,000-fold less potent against the cyclin B/CDK1 complex .
Cat. No.: HY-P4531
CAS No.: 21435-27-8
Target:
Research Areas:
Cat. No.: HY-W099536
CAS No.: 5274-68-0
Synonyms: Tetraoxyethylene glycol monododecyl ether
Target:
Research Areas:
PEG-4 lauryl ether is a non-ionic detergent that can be used as an excipient or for the isolation of functional membrane complexes .
Cat. No.: HY-W002040
CAS No.: 616-30-8
Synonyms: 1-Aminoglycerol, 97%
Target:
Research Areas:
dCeMM3 (Compound 3) is a molecular glue degrader. dCeMM3 induces ubiquitination and degradation of cyclin K by prompting an interaction of CDK12-cyclin K with a CRL4B ligase complex .
Target:
Research Areas:
Myosin V-IN-1 (compound 8) is a potent and selective Myosin V inhibitor, with a Ki of 6 μM. Myosin V-IN-1 shows acute inhibition of myosin V. Myosin V-IN-1 slows the actin-activated myosin V ATPase by specifically inhibiting ADP release from the actomyosin complex .
Synonyms: LEE011-d6 hydrochloride
Cat. No.: HY-N14514
CAS No.: 36889-17-5
Category:
Target:
Cat. No.: HY-16562S1
CAS No.: 718612-62-5
Target:
Research Areas:
CJJ300 is a transforming growth factor-β (TGF-β) inhibitor with an IC50 of 5.3 µM. CJJ300 inhibits TGF-β signaling by disrupting the formation of the TGF-β-TβR-I-TβR-II signaling complex .
Cat. No.: HY-114299R
CAS No.: 203787-91-1
Synonyms: SNAC (Standard)
Research Areas:
Salcaprozate (sodium) (Standard) is the analytical standard of Salcaprozate (sodium). This product is intended for research and analytical applications. Salcaprozate sodium (SNAC), an oral absorption promoter, and has the potential as a delivery agent for oral forms of heparin and insulin. Salcaprozate sodium could increase passive transcellular permeation across small intestinal epithelia based on increased lipophilicity arising from non-covalent macromolecule complexation .
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
