1268273-23-9
1268273-23-9
Chemical Structure
YK5
- CAS. Nr.: 1268273-23-9
- Formula:C18H24N8O3S
- Molecular Weight:432.50
IUPAC Name: N-(6-amino-2-((4,6-dimethoxy-2-(4-methylpiperazin-1-yl)pyrimidin-5-yl)thio)pyrimidin-4-yl)acrylamide
InChIKey: ZYAVZIQPWICPQI-UHFFFAOYSA-N
SMILES: C=CC(NC1=NC(SC2=C(OC)N=C(N3CCN(C)CC3)N=C2OC)=NC(N)=C1)=O
Biological Activity: YK5 is a potent and selective Hsp70 inhibitor. YK5 selectively and tightly binds to the cytosolic Hsp70s in cancer cells. YK5 has biological activity partly by interfering with the formation of active oncogenic Hsp70/Hsp90/client protein complexes[1].
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YK5 | 99.66% | YK5 is a potent and selective Hsp70 inhibitor. YK5 selectively and tightly binds to the cytosolic Hsp70s in cancer cells. YK5 has biological activity partly by interfering with the formation of active oncogenic Hsp70/Hsp90/client protein complexes. | ||||||||||||||||||||
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