Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
151 Results for "
LAP
" in MedChemExpress (MCE) Product Catalog:
Products (151)
151 Results for "LAP" in MCE Product Catalog:
Cat. No.: HY-RS17812
Target:
Research Areas:
Lap3 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Lap3 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Synonyms: L-APB monohydrate
Target:
Research Areas:
L-AP4 (L-APB) monohydrate is a potent and specific agonist for the group III mGluRs, with EC50s of 0.13, 0.29, 1.0, 249 μM for mGlu4, mGlu8, mGlu6 and mGlu7 receptors, respectively .
Cat. No.: HY-P10974
Target:
Research Areas:
Cat. No.: HY-P99913
CAS No.: 1384099-30-2
Target:
Research Areas:
Cat. No.: HY-RS16321
Target:
Research Areas:
LAP Human Pre-designed siRNA Set A contains three designed siRNAs for LAP gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS24280
Target:
Research Areas:
Lap3 Rat Pre-designed siRNA Set A contains three designed siRNAs for Lap3 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-158690
CAS No.: 338965-07-4
Target:
Research Areas:
DDD00057570 is a selective M17 leucyl-aminopeptidase (LAP) inhibitor. DDD00057570 inhibits L. major and L. donovani intracellular amastigotes in vitro growth .
Cat. No.: HY-100714B
CAS No.: 79055-67-7
Synonyms: L-APV; L-2-Amino-5-phosphonovaleric acid
Target:
Research Areas:
L-AP5 (L-APV; L-2-Amino-5-phosphonovaleric acid) is an NMDA antagonist and is the isomer of D-AP5 (HY-100714A).
L-AP5 shows a relatively weak amino acid and synaptic blocking activity .
Cat. No.: HY-100843
CAS No.: 78944-89-5
Target:
Research Areas:
L-AP6 is a selective agonist for a quisqualate-sensitized site in hippocampal CA1 pyramidal neurons .
Cat. No.: HY-RS00187
Target:
Research Areas:
ACP2 Human Pre-designed siRNA Set A contains three designed siRNAs for ACP2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS10478
Target:
Research Areas:
PICALM Human Pre-designed siRNA Set A contains three designed siRNAs for PICALM gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-W795259
CAS No.: 66254-56-6
Target:
Research Areas:
L-Val-P is a potent leucine aminopeptidase (LAP) inhibitor with a Ki of 0.15 μM. L-Val-P is promising for research of HIV infection, inflammation, eye lens cataract and cancer .
Cat. No.: HY-RS21289
Target:
Research Areas:
Acp3 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Acp3 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS02482
Target:
Research Areas:
CENPJ Human Pre-designed siRNA Set A contains three designed siRNAs for CENPJ gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-158227
Synonyms: DexMA (MW 200000)
Application: cell culture, biological 3D printing, tissue engineering, etc.
Cat. No.: HY-181017
Research Areas:
Ola-NC-SS-PEG-Lap is a selective immunogenic cell death inducer. Ola-NC-SS-PEG-Lap exploits the synergistic interplay between an NQO1-bioactivated compound and a PARP inhibitor to selectively induce immunogenic cell death in tumor cells without harming normal cells. Ola-NC-SS-PEG-Lap induces ROS accumulation, increases DNA damage. Ola-NC-SS-PEG-Lap can be activated by GSH and release Ola, ultimately producing the synergistic antitumor effect with the Lap portion. Ola-NC-SS-PEG-Lap has anti-cancer activity against colon cancer .
Cat. No.: HY-P702168
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: Probable cytosol aminopeptidase; 3.4.11.1; Leucine aminopeptidase; LAP; Leucyl aminopeptidase; 3.4.11.10; pepA
Species:
Others
Source:
E. coli
Cat. No.: HY-P702169
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: Probable cytosol aminopeptidase; 3.4.11.1; Leucine aminopeptidase; LAP; Leucyl aminopeptidase; 3.4.11.11; pepA
Species:
Others
Source:
E. coli
Cat. No.: HY-D3067
Target:
Research Areas:
ASSI-Leu is a novel AIE fluorescent probe based on an asymmetric tetraaryl imidazole skeleton, which can be used for ratiometric imaging detection of endogenous leucine aminopeptidase. ASSI-Leu contains an L-leucine-based recognition group that blocks the excited-state intramolecular proton transfer (ESIPT) in its 2-(2'-hydroxyphenyl) benzothiazole (HBT) skeleton, thereby generating an enol-form emission signal at Ex/Em = 365/417 nm. ASSI-Leu undergoes cleavage of the L-leucine group mediated by LAP to form ASSI-OH, which further activates aggregation-induced emission (AIE) and ESIPT, generating a keto-form emission signal at Ex/Em = 365/554 nm and producing a ratiometric fluorescent signal. ASSI-Leu enables real-time tracking of LAP in cancer cells and zebrafish models .\n
Cat. No.: HY-182611
CAS No.: 1637468-93-9
Target:
Research Areas:
SRI-31277 is a thrombospondin 1 (TSP-1) inhibitor with a human target pIC50 of 8.28 nM and in vivo activity, and exhibits a very short plasma half-life with intravenous administration.SRI-31277 inhibits interaction between TSP-1 and the latency-associated peptide (LAP) of latent TGF-β, blocking TSP-1-mediated TGF-β activation.SRI-31277 can be used for the research of multiple myeloma and fibrotic conditions .
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
