Ola-NC-SS-PEG-Lap
Ola-NC-SS-PEG-Lap is a selective immunogenic cell death inducer. Ola-NC-SS-PEG-Lap exploits the synergistic interplay between an NQO1-bioactivated compound and a PARP inhibitor to selectively induce immunogenic cell death in tumor cells without harming normal cells. Ola-NC-SS-PEG-Lap induces ROS accumulation, increases DNA damage. Ola-NC-SS-PEG-Lap can be activated by GSH and release Ola, ultimately producing the synergistic antitumor effect with the Lap portion. Ola-NC-SS-PEG-Lap has anti-cancer activity against colon cancer.
For research use only. We do not sell to patients.
- Formula: C55H63FN6O16S2
- Molecular Weight:1147.25
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
- Purity & Documentation
- References
-
Help & FAQs
All DNA/RNA Synthesis Isoforms
More
Biological Activity
|
NQO1 |
Chemical Information
-
Molecular Weight 1147.25
-
Formula C55H63FN6O16S2
-
SMILES
O=C1N(N=C(C2=CC=CC=C21)CC3=CC=C(C(C(N4CCN(CC4)C(C5CC5)=O)=O)=C3)F)CNC(OCCSSCCOC(NCCOCCOCCOCCOC(OC6CC7=C(C8=CC=CC=C8C(C7=O)=O)OC6(C)C)=O)=O)=O
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Ola-NC-SS-PEG-Lap Related Classifications
HY-181017 Related Classifications
Powered by Bioz