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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
46 Results for "
ewing sarcoma
" in MedChemExpress (MCE) Product Catalog:
Products (46)
46 Results for "ewing sarcoma" in MCE Product Catalog:
Cat. No.: HY-183858
CAS No.: 1964516-59-3
Target:
Research Areas:
NCATS-SM1440 is a glycolysis inhibitor and metabolic regulator that targets LDHA and LDHB (IC50=0.06 μM and 0.03 μM, respectively). Upon binding to LDHA, NCATS-SM1440 blocks the glycolysis pathway and reduces lactate production. NCATS-SM1440 drives the shift of pyruvate metabolism toward mitochondrial metabolism, effectively disrupting the dependence of cancer cells on aerobic glycolysis. NCATS-SM1440 can be widely used in research related to cancer, Ewing's sarcoma, and other related conditions .
Cat. No.: HY-P703126
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: FLI1; Transcription Factor ERGB; Fli-1 Proto-Oncogene, ETS Transcription Factor; ewing sarcoma Breakpoint Region 2; SIC-1; ERGB Transcription Factor; EWSR2; ERGB Transcription Fuctor; FLI-1; Proto-Oncogene Fli-1; Friend Leukemia Integration 1 Transcriptio
Species:
Human
Source:
E. coli
Cat. No.: HY-P703127
Purity: ≥ 80%, as determined by reducing SDS-PAGE.
Synonyms: FLI1; Transcription Factor ERGB; Fli-1 Proto-Oncogene, ETS Transcription Factor; ewing sarcoma Breakpoint Region 2; SIC-1; ERGB Transcription Factor; EWSR2; ERGB Transcription Fuctor; FLI-1; Proto-Oncogene Fli-1; Friend Leukemia Integration 1 Transcriptio
Species:
Human
Source:
E. coli
Cat. No.: HY-188148
CAS No.: 158437-84-4
Target:
Research Areas:
ETS transcription factor-IN-1 is an inhibitor of ETS transcription factor. ETS transcription factor-IN-1 blocks the binding of the ETS DNA-binding domain to consensus ETS DNA-binding sites, thereby inhibiting the function of ETS transcription factors such as ETV6, ERG, and FLI1. ETS transcription factor-IN-1 inhibits angiogenesis and tumor cell proliferation in cancer cell lines with ETS abnormalities. ETS transcription factor-IN-1 can be used in research related to prostate cancer and breast cancer .
Cat. No.: HY-P75921
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: MAP3K8; Proto-Oncogene Serine/Threoine Protein Kinase; Prev. ESTF; Cot (Cancer Osaka Thyroid) Oncogene; Prev. COT; Serine/Threonine-Protein Kinase Cot; Tumor Progression Locus 2; Cancer Osaka Thyroid Oncogene; Tpl-2; ewing sarcoma Transformant; C-COT; AUR
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-145514R
CAS No.: 2624313-15-9
Target:
Research Areas:
dTAGV-1 TFA (Standard) is the analytical standard of dTAGV-1 TFA (HY-145514). This product is intended for research and analytical applications. dTAGV-1 TFA is a selective FKBP12 F36V PORTAC degrader. dTAGV-1 TFA induces rapid degradation of FKBP12 F36V-tagged oncogenic fusion proteins, triggering collapse of downstream cellular signaling pathways, reduced proliferative capacity of cancer cells, and decreased levels of target proteins. dTAGV-1 TFA is applicable to functional validation studies of cancer and undegradable oncoproteins .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
