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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
109 Results for "
Integrin beta 3
" in MedChemExpress (MCE) Product Catalog:
Products (109)
109 Results for "Integrin beta 3" in MCE Product Catalog:
Cat. No.: HY-126039
CAS No.: 168157-33-3
Target:
Research Areas:
L-739758 is an antagonist for αIIbβ3 integrin (platelet glycoprotein IIb/IIIa). L-739758 acts as a peptidomimetic, binds to αIIbβ3 integrin by mimicking the interaction of the RGD (arginine-glycine-aspartic acid) motif, and is involved in the blood coagulation process. L-739758 inhibits platelet aggregation, and is used for thrombosis research .
Cat. No.: HY-126402
CAS No.: 120103-89-1
Arg-Gly-Asp (RGD) is a synthetic peptide corresponding to the cell adhesion sequence for the integrins αVβ1, αVβ3, αVβ5, αVβ6, αVβ8, α8β1, and α5β1. It is a component of radioligands and peptidomimetics that have been used in the study of integrin expression and activity in vivo.
Cat. No.: HY-124499
CAS No.: 796886-30-1
Target:
Research Areas:
RUC-1 (Compound 1) is an inhibitor for αIIbβ3 integrin. RUC-1 inhibits fibrin deposition and platelet aggregation in hybrid hαIIb/mβ3 receptors expressing mice. RUC-1 exhibits antithrombotic effect in hαIIb/mβ3 receptor expressing mice .
Cat. No.: HY-P10038
CAS No.: 2700321-79-3
Synonyms: Myr-FEEERA-OH
Cat. No.: HY-P0295A
CAS No.: 2828433-23-2
Synonyms: GRGDS TFA
Target:
Research Areas:
Cat. No.: HY-122552
CAS No.: 108853-09-4
Target:
Cat. No.: HY-164981
CAS No.: 1703752-99-1
Target:
Research Areas:
p-SCN-Bn-DOTA(tBu)4 is the derivative of DOTA (HY-W053583). p-SCN-Bn-DOTA(tBu)4 is the component of the Gd(III)-DOTA-IAC, which is a targeted magnetic resonance imaging (MRI) contrast agent for αvβ3 integrin receptor .
PAWI-2 is a p53-Activator and Wnt Inhibitor. PAWI-2 inhibits β3-KRAS signaling independent of KRAS. PAWI-2 selectively inhibits phosphorylation of TBK1. PAWI-2 activates apoptosis (activation of caspase-3/7), and induces PARP cleavage. PAWI-2 promotes optineurin translocation into the nucleus and causes G2/M arrest. PAWI-2 reverses cancer stemness and overcomes drug resistance in an integrin β3 KRAS-dependent human pancreatic cancer stem cells (hPCSCs). PAWI-2 inhibits growth of tumors from hPCSCs in orthopic xenograft mice model .
Cat. No.: HY-P700760
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: ITGAV; Integrin, Alpha V (Vitronectin Receptor, Alpha Polypeptide, Antigen CD51); Prev. MSK8; Vitronectin Receptor; Prev. VNRA; Integrin AlphaVbeta3; Prev. VTNR; Integrin, Alpha V; Vitronectin Receptor Subunit Alpha; CD51 Antigen; Integrin Alpha-V; IDNDC
Species:
Mouse
Source:
HEK293
Cat. No.: HY-P700761
Purity: ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: ITGAV; Integrin, Alpha V (Vitronectin Receptor, Alpha Polypeptide, Antigen CD51); Prev. MSK8; Vitronectin Receptor; Prev. VNRA; Integrin AlphaVbeta3; Prev. VTNR; Integrin, Alpha V; Vitronectin Receptor Subunit Alpha; CD51 Antigen; Integrin Alpha-V; IDNDC
Species:
Mouse
Source:
HEK293
Cat. No.: HY-P701063
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: ITGAV; Integrin, Alpha V (Vitronectin Receptor, Alpha Polypeptide, Antigen CD51); Prev. MSK8; Vitronectin Receptor; Prev. VNRA; Integrin AlphaVbeta3; Prev. VTNR; Integrin, Alpha V; Vitronectin Receptor Subunit Alpha; CD51 Antigen; Integrin Alpha-V; IDNDC
Species:
Cynomolgus
Source:
HEK293
Cat. No.: HY-P73868
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: ITGAV; Integrin, Alpha V (Vitronectin Receptor, Alpha Polypeptide, Antigen CD51); Prev. MSK8; Vitronectin Receptor; Prev. VNRA; Integrin AlphaVbeta3; Prev. VTNR; Integrin, Alpha V; Vitronectin Receptor Subunit Alpha; CD51 Antigen; Integrin Alpha-V; IDNDC
Species:
Human
Source:
HEK293
Cat. No.: HY-P700765
Purity: ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: ITGAV; Integrin, Alpha V (Vitronectin Receptor, Alpha Polypeptide, Antigen CD51); Prev. MSK8; Vitronectin Receptor; Prev. VNRA; Integrin AlphaVbeta3; Prev. VTNR; Integrin, Alpha V; Vitronectin Receptor Subunit Alpha; CD51 Antigen; Integrin Alpha-V; IDNDC
Species:
Human
Source:
HEK293
Cat. No.: HY-P701015
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: ITGAV; Integrin, Alpha V (Vitronectin Receptor, Alpha Polypeptide, Antigen CD51); Prev. MSK8; Vitronectin Receptor; Prev. VNRA; Integrin AlphaVbeta3; Prev. VTNR; Integrin, Alpha V; Vitronectin Receptor Subunit Alpha; CD51 Antigen; Integrin Alpha-V; IDNDC
Species:
Mouse
Source:
HEK293
Cat. No.: HY-P73868A
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: ITGAV; Integrin, Alpha V (Vitronectin Receptor, Alpha Polypeptide, Antigen CD51); Prev. MSK8; Vitronectin Receptor; Prev. VNRA; Integrin AlphaVbeta3; Prev. VTNR; Integrin, Alpha V; Vitronectin Receptor Subunit Alpha; CD51 Antigen; Integrin Alpha-V; IDNDC
Species:
Human
Source:
HEK293
Cat. No.: HY-P700754
Purity: ≥ 95%, as determined by reducing Tris-Bis PAGE.
Synonyms: ITGA2B; Platelet Fibrinogen Receptor, Alpha Subunit; Prev. GP2B; Platelet Glycoprotein IIb; GPIIb; AlphaIIb Protein; Integrin Alpha-IIb; Glycoprotein IIb; PPP1R93; CD41 Antigen; CD41B; BDPLT16; CD41; BDPLT2; Integrin, Alpha 2b (Platelet Glycoprotein IIb O
Species:
Mouse
Source:
HEK293
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
