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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
121 Results for "
cGAS
" in MedChemExpress (MCE) Product Catalog:
Products (121)
121 Results for "cGAS" in MCE Product Catalog:
Cat. No.: HY-116214S
CAS No.: 1773496-67-5
Synonyms: CGA-219417-d5
Cat. No.: HY-116214S1
CAS No.: 1773496-63-1
Synonyms: CGA-219417-13C6
Cat. No.: HY-114730
CAS No.: 1621626-06-9
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CGA-JK3 is CGA-JK3 is an ATP-competitive inhibitor of IKKβ-catalyzed kinase activity. CGA-JK3 inhibits IκBα phosphorylation in LPS (HY-D1056) - induced RAW 264.7 cells .
Cat. No.: HY-12464R
CAS No.: 134605-64-4
Synonyms: WC-9717 (Standard); CGA-276854 (Standard)
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Butafenacil (Standard) is the analytical standard of Butafenacil. This product is intended for research and analytical applications. Butafenacil (WC-9717; CGA-276854) is an herbicide that inhibits protoporphyrinogen oxidase .
Cat. No.: HY-RS02575
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CGA Human Pre-designed siRNA Set A contains three designed siRNAs for CGA gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS17789
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Research Areas:
Cga Mouse Pre-designed siRNA Set A contains three designed siRNAs for Cga gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS24257
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Cga Rat Pre-designed siRNA Set A contains three designed siRNAs for Cga gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-W010319S
CAS No.: 2377723-87-8
Synonyms: CGA-150829-d3
Cat. No.: HY-184398
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cGAS/HDAC-IN-1 is an orally active dual cGAS/HDAC inhibitor that exhibits potent inhibitory activity against human and mouse cGAS (IC50: 0.17 and 1.80 μM, respectively) and moderate activity against HDAC3 and HDAC6 (IC50: 1.2 and 0.4 μM, respectively). cGAS/HDAC-IN-1 directly suppresses cGAS activity and increases its acetylation levels via HDAC3 inhibition. cGAS/HDAC-IN-1 is effective in murine models of inflammatory bowel disease and Aicardi-Goutières syndrome, and can be used in research on cGAS-dependent disorders .
Cat. No.: HY-B1331R
CAS No.: 66215-27-8
Synonyms: Cyromazin (Standard); CGA-72662 (Standard)
Category:
Cat. No.: HY-150751A
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Biotin-labeled ODN TTAGGG (sodium), a inhibitory oligonucleotide (ODN), is a TLR9, AIM2 and cGAS antagonist. Biotin-labeled ODN TTAGGG (sodium) can be used to evaluate CpG ODN cellular uptake and localization using a biotin detection system and light microscopy.
Cat. No.: HY-N12507
CAS No.: 2968309-12-6
Category:
Alkaloids Strychnos nux-vomica Linn. Monophenols Loganiaceae Phenols Plants Indole Alkaloids
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Cat. No.: HY-P3041
CAS No.: 133633-11-1
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Cat. No.: HY-150751B
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Research Areas:
FITC-labeled ODN TTAGGG (sodium), a inhibitory oligonucleotide (ODN), is a TLR9, AIM2 and cGAS antagonist. FITC-labeled ODN TTAGGG (sodium) can be used to evaluate CpG ODN cellular uptake and localization by confocal laser-scanning microscopy (excitation 495 nm, emission 520 nm) or flow cytometry.
Cat. No.: HY-158126
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G-quadruplex ligand 2 (compound A3) is a triphenylamine-based ligand that targets mitochondrial DNA G4s. G-quadruplex ligand 2 activates the cGAS-STING pathway. G-quadruplex ligand 2 inhibits tumor growth and metastasis via regulation of TME .
Cat. No.: HY-123230S1
Synonyms: CGA 279202-d3
Cat. No.: HY-175472
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(GalNAc)3-CPT is a glycoconjugate prodrug that targets the asialoglyco-protein receptor (ASGR) overexpressed on hepatocytes. (GalNAc)3-CPT exhibits significant antitumor activity (IC50 value of 3.07 μM in HepG2 cells) by activating the cGAS-STING pathway and promoting CD8+ T cell infiltration into tumors, thereby inducing tumor cell apoptosis .
Cat. No.: HY-144328
CAS No.: 2259308-69-3
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STING agonist-10 (Compound 91) is a potent small molecule cyclic urea activator of STING with the EC50 of 2600 nM. Activation of STING is a highly promising approach in immunotherapy .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
