(GalNAc)3-CPT
(GalNAc)3-CPT is a glycoconjugate prodrug that targets the asialoglyco-protein receptor (ASGR) overexpressed on hepatocytes. (GalNAc)3-CPT exhibits significant antitumor activity (IC50 value of 3.07 μM in HepG2 cells) by activating the cGAS-STING pathway and promoting CD8+ T cell infiltration into tumors, thereby inducing tumor cell apoptosis.
For research use only. We do not sell to patients.
- Formula: C93H141N15O33
- Molecular Weight:1997.20
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
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- References
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Help & FAQs
Biological Activity
Chemical Information
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Molecular Weight 1997.20
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Formula C93H141N15O33
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SMILES
O[C@@H]1[C@H]([C@@H](O[C@@H](C1O)CO)OCCCCC(NCCCNC(CCOCC(NC(CCCCCN2C=C(N=N2)CCCC(O[C@@]3(C(OCC4=C3C=C5C6=NC(C=CC=C7)=C7C=C6CN5C4=O)=O)CC)=O)=O)(COCCC(NCCCNC(CCCCO[C@H]8[C@@H]([C@H](C([C@H](O8)CO)O)O)NC(C)=O)=O)=O)COCCC(NCCCNC(CCCCO[C@H]9[C@@H]([C@H](C([C@H](O9)CO)O)O)NC(C)=O)=O)=O)=O)=O)NC(C)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
(GalNAc)3-CPT Related Classifications
HY-175472 Related Classifications
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