125-15-5
125-15-5
Chemical Structure
Vomicine
- CAS No.: 125-15-5
- Formula:C22H24N2O4
- Molecular Weight:380.44
IUPAC Name: (4aR,4a1R,6aS,6a1S,13aS)-10-hydroxy-16-methyl-4a,4a1,5,6a1,13,13a-hexahydro-12H-6a,4-(ethanoiminomethano)indolo[3,2,1-ij]oxepino[2,3,4-de]quinoline-6,12(2H)-dione
InChIKey: ZMTYENXGROJCEA-LNKPQSDASA-N
SMILES: O=C1[C@@]23[C@](N4C5=C(O)C=CC=C35)([H])[C@@]6([H])[C@@](C(CN(C)CC2)=CCO[C@@]6([H])CC4=O)([H])C1
Biological Activity: Vomicine modulates cGAS-STING-TBK1 signaling pathway, and exhibits anti-inflammatory activity. Vomicine is an alkaloid that can be isolated from Strychnos nux-vomica seeds[1][2].
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Vomicine | 99.85% | Vomicine modulates cGAS-STING-TBK1 signaling pathway, and exhibits anti-inflammatory activity. Vomicine is an alkaloid that can be isolated from Strychnos nux-vomica seeds. | ||||||||||||||||||||
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Vomicine (Standard) | ≥98% | Vomicine (Standard) is the analytical standard of Vomicine. This product is intended for research and analytical applications. Vomicine modulates cGAS-STING-TBK1 signaling pathway, and exhibits anti-inflammatory activity. Vomicine is an alkaloid that can be isolated from Strychnos nux-vomica seeds. | ||||||||||||||||||||
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References
- [1]. Bhati R, et al. Strychnos nux-vomica seeds: Pharmacognostical standardization, extraction, and antidiabetic activity. J Ayurveda Integr Med. 2012 Apr;3(2):80-4. [Content Brief]
- [2]. Zhan Y, et al., Semen Strychni Pulveratum and vomicine alleviate neuroinflammation in amyotrophic lateral sclerosis through cGAS-STING-TBK1 pathway. J Ethnopharmacol. 2025 Jan 10;336:118741. [Content Brief]
