Loganiaceae

Koumine is an alkaloid separated from Gelsemium elegans, shows potent anti-tumor activity. Koumine up-regulates the Bax/Bcl-2 ratio and caspase-3 expression in human breast cancer cells. Koumine has anxiolytic, antistress, antipsoriatic, and analgesic activities, protects against the development of arthritis in Rheumatoid arthritis (RA) animal models.

Gelsemine, an alkaloid from the Chinese herb Gelsemium elegans, is effective in mitigating chronic pain. Antinociceptive effects.

Vomicine modulates cGAS-STING-TBK1 signaling pathway, and exhibits anti-inflammatory activity. Vomicine is an alkaloid that can be isolated from Strychnos nux-vomica seeds.

(Z)-Akuammidine ((Z)-Rhazine) is isolated from Gelsemium elegans.

Gelsevirine is the major alkaloid in Gelsemium elegans with potent anxiolytic effects. The anxiolytic mechanism of Gelsevirine may be involved in the agonist action of the glycine receptor in the brain. Gelsevirine has anti-proliferation activity with IC₅₀ values of 1.41 mM and 1.22 mM for SW480 cells and MGC80-3 cells, respectively.

Secostrychnosin is a secoiridoid found in the stem of Strychnos cathayensis.

Taberpsychine is a natural alkaloid.

Gelse-norursane B is a natural triterpene.

Koumine (Standard) is the analytical standard of Koumine. This product is intended for research and analytical applications. Koumine is an alkaloid separated from Gelsemium elegans, shows potent anti-tumor activity. Koumine up-regulates the Bax/Bcl-2 ratio and caspase-3 expression in human breast cancer cells. Koumine has anxiolytic, antistress, antipsoriatic, and analgesic activities, protects against the development of arthritis in Rheumatoid arthritis (RA) animal models.

Longicautadine is a bisindole alkaloid that can be isolated from the root and stem bark of Strychnos nux vomica.

Venoterpine (RW 47) is a natural product. Venoterpine shows anti-aging activities.

Koumine N-oxide is an alkaloid compound isolated from the herb Gelsemium elegans.

Gelsempervine A (16-epi-Nb-Methylvoacarpine) is a natural product that can be isolated from Gelsemium elegans.

Rankinidine is an oxindole alkaloid that is isolated from the MeOH extract of the stem of Gelsemium rankinii.

Humantenirine is an indole alkaloid isolated from Gelsemium sempervirens.

Sempervirine is an indole alkaloid isolated from Gelsemium sempervirens with anti-tumor activities. Sempervirine is against sempervirine-sensitive tumor cells with EC₅₀ values of 2.7 μM, 1.77 μM, and 1.96 μM for Raji, MDA-MB-231 and HeLa cells, respectively.

16-Methoxystrychnine is a alkaloid.

Bakankosin (Bakankosine) is a monoterpene glycoside that can be isolated from Strychnos nux vomica .

Strychnospermine is an alkaloid that has been found in S. psilosperma.

7-Deoxy-10-hydroxyloganetin is a Iridoids product that can be isolated from the seeds of Strychnos nux-vomica.