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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
78 Results for "
ALK2
" in MedChemExpress (MCE) Product Catalog:
Products (78)
78 Results for "ALK2" in MCE Product Catalog:
Cat. No.: HY-P991855
Target:
Research Areas:
Cat. No.: HY-12071R
CAS No.: 1062368-24-4
Synonyms: DM-3189 (Standard)
Research Areas:
LDN193189 (Standard) is the analytical standard of LDN193189 (HY-12071). This product is intended for research and analytical applications. LDN193189 (DM-3189) is a potent selective BMP type I receptor (BMP I) inhibitor. LDN193189 efficiently inhibits transcriptional activity of the BMP type I receptors ALK2 and ALK3 with IC50 values of 5 nM and 30 nM, respectively. LDN193189 can be used for the research of bone morphogenetic protein signalling, such as fibrodysplasia ossificans progressiva [2] .
Cat. No.: HY-RS00236
Target:
Research Areas:
ACVR1 Human Pre-designed siRNA Set A contains three designed siRNAs for ACVR1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-109179AR
CAS No.: 2409543-84-4
Synonyms: TP-0184 hydrochloride (Standard)
Target:
JAK Reference Standards Anaplastic lymphoma kinase (ALK) FLT3 STAT PI3K Akt mTOR TGF-beta/Smad TGF-β Receptor
Research Areas:
Itacnosertib hydrochloride (Standard) is the analytical standard of Itacnosertib (hydrochloride) (HY-109179A). This product is intended for research and analytical applications. Itacnosertib hydrochloride (TP-0184 hydrochloride) is the inhibitor for FLT3, ACVR1 (ALK2, IC50=8 nM) and JAK2 (IC50=8540 nM). Itacnosertib hydrochloride exhibits anti-leukemic activity [2].
Cat. No.: HY-109179R
CAS No.: 1628870-27-8
Synonyms: TP-0184 (Standard)
Target:
Reference Standards JAK Anaplastic lymphoma kinase (ALK) FLT3 STAT PI3K Akt mTOR TGF-beta/Smad TGF-β Receptor
Research Areas:
Itacnosertib (Standard) is the analytical standard of Itacnosertib (HY-109179). This product is intended for research and analytical applications. Itacnosertib (TP-0184) is the inhibitor for FLT3, ACVR1 (ALK2, IC50=8 nM) and JAK2 (IC50=8540 nM). Itacnosertib exhibits anti-leukemic activity [2].
Cat. No.: HY-151277
CAS No.: 2785430-85-3
Target:
Research Areas:
ALK5-IN-29 is an selective activin receptor-like kinase (ALK) inhibitor. ALK5-IN-29 can inhibit the activity of ALK5 with an IC50 value of ≤10 nM. ALK5-IN-29 also has inhibitory of tumor growth and can be used for the research of proliferative diseases, such as cancer .
Cat. No.: HY-19928R
CAS No.: 1352608-82-2
Synonyms: EW-7197 (Standard); TEW-7197 (Standard)
Target:
Research Areas:
Vactosertib (Standard) is the analytical standard of Vactosertib (HY-19928). This product is intended for research and analytical applications. Vactosertib (EW-7197) is a potent, orally active and ATP-competitive activin receptor-like Kinase 5 (ALK5) inhibitor with an IC50 of 12.9 nM. Vactosertib also inhibits ALK2 and ALK4 (IC50 of 17.3 nM) at nanomolar concentrations. Vactosertib has potently antimetastatic activity and anticancer effect [2].
Cat. No.: HY-13418AR
CAS No.: 866405-64-3
Synonyms: BML-275 (Standard)
Research Areas:
Dorsomorphin (Standard) is the analytical standard of Dorsomorphin (HY-13418A). This product is intended for research and analytical applications. Dorsomorphin (BML-275) is a selective and ATP-competitive AMPK inhibitor (Ki=109 nM in the absence of AMP). Dorsomorphin (BML-275) selectively inhibits BMP type I receptors ALK2, ALK3, and ALK6. Dorsomorphin can reverse autophagy activation and anti-inflammatory effect of Urolithin A (HY-100599) [2].
Cat. No.: HY-12278G
CAS No.: 1431985-92-0
Cat. No.: HY-P72812
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: ACVR1; Activin A Receptor, Type II-Like Kinase 2; Prev. ACVRLK2; Receptor Protein Serine/Threonine Kinase; SKR1; HydroxyALKyl-Protein Kinase; TGF-B Superfamily Receptor Type I; Alternative Protein ACVR1; Activin Receptor Type-1; ACTR-I; Activin Receptor T
Species:
Human
Source:
HEK293
Cat. No.: HY-P72769
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: ACVR1; Activin A Receptor, Type II-Like Kinase 2; Prev. ACVRLK2; Receptor Protein Serine/Threonine Kinase; SKR1; HydroxyALKyl-Protein Kinase; TGF-B Superfamily Receptor Type I; Alternative Protein ACVR1; Activin Receptor Type-1; ACTR-I; Activin Receptor T
Species:
Human
Source:
HEK293
Cat. No.: HY-P7482
Purity: ≥ 80%, as determined by reducing SDS-PAGE.
Synonyms: ACVR1; Activin A Receptor, Type II-Like Kinase 2; Prev. ACVRLK2; Receptor Protein Serine/Threonine Kinase; SKR1; HydroxyALKyl-Protein Kinase; TGF-B Superfamily Receptor Type I; Alternative Protein ACVR1; Activin Receptor Type-1; ACTR-I; Activin Receptor T
Species:
Human
Source:
HEK293
Cat. No.: HY-P705731
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: ACVR1; Activin A Receptor, Type II-Like Kinase 2; Prev. ACVRLK2; Receptor Protein Serine/Threonine Kinase; SKR1; HydroxyALKyl-Protein Kinase; TGF-B Superfamily Receptor Type I; Alternative Protein ACVR1; Activin Receptor Type-1; ACTR-I; Activin Receptor T
Species:
Human
Source:
sf9 insect cells
Cat. No.: HY-P705732
Purity: ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: ACVR1; Activin A Receptor, Type II-Like Kinase 2; Prev. ACVRLK2; Receptor Protein Serine/Threonine Kinase; SKR1; HydroxyALKyl-Protein Kinase; TGF-B Superfamily Receptor Type I; Alternative Protein ACVR1; Activin Receptor Type-1; ACTR-I; Activin Receptor T
Species:
Human
Source:
sf9 insect cells
Cat. No.: HY-P705733
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: ACVR1; Activin A Receptor, Type II-Like Kinase 2; Prev. ACVRLK2; Receptor Protein Serine/Threonine Kinase; SKR1; HydroxyALKyl-Protein Kinase; TGF-B Superfamily Receptor Type I; Alternative Protein ACVR1; Activin Receptor Type-1; ACTR-I; Activin Receptor T
Species:
Human
Source:
sf9 insect cells
Cat. No.: HY-P705734
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: ACVR1; Activin A Receptor, Type II-Like Kinase 2; Prev. ACVRLK2; Receptor Protein Serine/Threonine Kinase; SKR1; HydroxyALKyl-Protein Kinase; TGF-B Superfamily Receptor Type I; Alternative Protein ACVR1; Activin Receptor Type-1; ACTR-I; Activin Receptor T
Species:
Human
Source:
sf9 insect cells
Cat. No.: HY-P705735
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: ACVR1; Activin A Receptor, Type II-Like Kinase 2; Prev. ACVRLK2; Receptor Protein Serine/Threonine Kinase; SKR1; HydroxyALKyl-Protein Kinase; TGF-B Superfamily Receptor Type I; Alternative Protein ACVR1; Activin Receptor Type-1; ACTR-I; Activin Receptor T
Species:
Human
Source:
sf9 insect cells
Cat. No.: HY-P705993
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: ACVR1; Activin A Receptor, Type II-Like Kinase 2; Prev. ACVRLK2; Receptor Protein Serine/Threonine Kinase; SKR1; HydroxyALKyl-Protein Kinase; TGF-B Superfamily Receptor Type I; Alternative Protein ACVR1; Activin Receptor Type-1; ACTR-I; Activin Receptor T
Species:
Human
Source:
sf9 insect cells
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
