1431985-92-0
1431985-92-0
Chemical Structure
K02288
- CAS No.: 1431985-92-0
- Formula:C20H20N2O4
- Molecular Weight:352.38
IUPAC Name: 3-(6-amino-5-(3,4,5-trimethoxyphenyl)pyridin-3-yl)phenol
InChIKey: CJLMANFTWLNAKC-UHFFFAOYSA-N
SMILES: OC1=CC=CC(C2=CC(C3=CC(OC)=C(OC)C(OC)=C3)=C(N)N=C2)=C1
Biological Activity: K02288 is a potent bone morphogenetic protein (BMP) type I receptor inhibitor with IC50s of 1.8, 1.1, 6.4 nM for ALK1, ALK2 and ALK6, respectively. K02288 shows slightly weaker inhibition against ALK3 and ALK6 with IC50s of of 5-34 nM.
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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K02288 | 99.95% | K02288 is a potent bone morphogenetic protein (BMP) type I receptor inhibitor with IC50s of 1.8, 1.1, 6.4 nM for ALK1, ALK2 and ALK6, respectively. K02288 shows slightly weaker inhibition against ALK3 and ALK6 with IC50s of of 5-34 nM. | ||||||||||||||||||||
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K02288 (GMP) | K02288 (GMP) is K02288 (HY-12278) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. K02288 is a potent bone morphogenetic protein (BMP) type I receptor inhibitor with IC50s of 1.8, 1.1, 6.4 nM for ALK1, ALK2 and ALK6, respectively. K02288 shows slightly weaker inhibition against ALK3 and ALK6 with IC50s of of 5-34 nM. | |||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.67
HY-168926NQO2-IN-1 -
Similarity Score 0.62
HY-16712LDN-214117 -
Similarity Score 0.59
HY-149591M4K-2009 -
Similarity Score 0.59
HY-149591AM4K2009 hydrochloride -
Similarity Score 0.58
HY-176941ALK2-IN-6 -
Similarity Score 0.58
HY-162807TMV-IN-10 -
Similarity Score 0.58
HY-179372Tubulin polymerization-IN-84 -
Similarity Score 0.57
HY-123965PF-06745013 -
Similarity Score 0.56
HY-155962Tubulin polymerization-IN-47 -
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