Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
72 Results for "
ASC
" in MedChemExpress (MCE) Product Catalog:
Products (72)
72 Results for "ASC" in MCE Product Catalog:
Cat. No.: HY-P86772
Synonyms: Activating signal cointegrator 1 antibody; ASC 1 antibody; ASC-1 antibody; HsT17391 antibody; Thyroid hormone receptor interactor 4 antibody; Thyroid receptor interacting protein 4 antibody; Thyroid receptor-interacting protein 4 antibody; TR-interacting protein 4 antibody; TR; IP : 4 antibody; TRIP-4 antibody; Activating signal cointegrator 1 antibody; ASC 1 antibody; ASC-1 antibody; HsT17391 antibody; Thyroid hormone receptor interactor 4 antibody; Thyroid receptor interacting protein 4 antibody; Thyroid receptor-interacting protein 4 antibody; TR-interacting protein 4 antibody; TR; IP : 4 antibody; TRIP-4 antibody; Trip4 antibody; TRIP4_HUMAN antibody; ZC2HC5 antibody; Zinc finger C2HC5 type antibody;
Cat. No.: HY-P88086A
Synonyms: ASC2; cPOP1; POP1; PYC1
Cat. No.: HY-P87932
Synonyms: ASC, CARD5, TMS1, PYCARD, Apoptosis-associated speck-like protein containing a CARD, hASC, Caspase recruitment domain-containing protein 5, PYD and CARD domain-containing protein, Target of methylation-induced silencing 1
Cat. No.: HY-179494
Target:
NOD-like Receptor (NLR) Pyroptosis Caspase Interleukin Related Reactive Oxygen Species (ROS)
Research Areas:
M464, a non-steroidal anti-inflammatory compound, is a potent and orally active NLRP3 inflammasome inhibitor. M464 inhibits pyroptosis and hinders the activation of downstream Caspase-1 expression and the release of IL-1β by impeding ASC oligomerisation and curtailing ROS production. M464 exhibits protective effects against acute lung and liver injury in mice. M464 can be used for the research of NLRP3-related inflammatory diseases .
Cat. No.: HY-128861B
CAS No.: 1403357-80-1
Synonyms: Dimethylaminomicheliolide hydrochloride; DMAMCL hydrochloride
Research Areas:
ACT001 (Dimethylaminomicheliolide; DMAMCL) hydrochloride is an orally active, blood-brain barrier-permeable anti-inflammatory and anti-tumor agent. ACT001 hydrochloride exerts microglia-mediated neuroanti-inflammatory effects by inhibiting the AKT/NF-κB/NLRP3 axis and suppressing apoptosis (apoptosis). ACT001 hydrochloride inhibits tumor proliferation by upregulating NKTR and inhibiting AKT. ACT001 hydrochloride alleviates metabolic-associated fatty liver disease by regulating gut microbiota and inhibiting ileal FXR. ACT001 hydrochloride inhibits pyroptosis (pyroptosis) and pro-inflammatory cytokine release by activating PPAR-γ and inhibiting NF-κB/NLRP3 .
Cat. No.: HY-189215
CAS No.: 3087067-85-1
Target:
Influenza Virus RIG-I-like receptor (RLR) Toll-like Receptor (TLR) NF-κB Interleukin Related IFNAR Apoptosis Reactive Oxygen Species (ROS)
Research Areas:
Anti-Influenza agent 12 is an orally active inhibitor of influenza A virus infection. Anti-Influenza agent 12 inhibits RIG-I-mediated innate immune signaling and TLR3-mediated signaling pathways. Anti-Influenza agent 12 inhibits NF-κB phosphorylation and downregulates the expression levels of IRF3, ASC, iNOS, IL-4, IL-6, and IFN-α inflammatory genes. Anti-Influenza agent 12 inhibits viral nucleoprotein (NP) and matrix protein 2 (M2) mRNA transcription and protein synthesis. Anti-Influenza agent 12 inhibits virus-induced apoptosis, reduces ROS and NO production, and maintains mitochondrial membrane potential. Anti-Influenza agent 12 exhibits broad-spectrum activity against H1N1 and H3N2 subtypes, reduces viral load, and alleviates lung tissue damage. Anti-Influenza agent 12 can be used for research on influenza A virus infection .
Cat. No.: HY-P703196
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: SLC1A5; ASC Amino Acid Transporter-2; Prev. M7V1; ATB(0); Prev. RDRC; Neutral Amino Acid Transporter B; ASCT2; Amino Acid Transporter; Neutral Amino Acid Transporter B(0); RD114 Virus Receptor; AAAT; M7VS1; Solute Carrier Family 1 (Neutral Amino Acid Tran
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-P704158
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: SLC1A5; ASC Amino Acid Transporter-2; Prev. M7V1; ATB(0); Prev. RDRC; Neutral Amino Acid Transporter B; ASCT2; Amino Acid Transporter; Neutral Amino Acid Transporter B(0); RD114 Virus Receptor; AAAT; M7VS1; Solute Carrier Family 1 (Neutral Amino Acid Tran
Species:
Human
Source:
E. coli
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
