PYDC1 Antibody (YA7770)(PBS only)
(Synonyms: ASC2; cPOP1; POP1; PYC1)PYDC1 Antibody (YA7770) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to PYDC1.
-
Host:
Mouse
-
Isotype:
IgG1
-
Application:
IHC-P
-
Reactivity :
Human
-
Formulation:
Supplied in PBS, pH 7.4.
-
Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
IHC-P
IHC-P: Immunohistochemistry-Paraffin
|
|---|---|
| Dilution Ratio | 1:150-500 |
Product Details
PYDC1 Antibody (YA7770) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to PYDC1.
-
Host Mouse
-
Species ReactivityHuman
Full length human recombinant protein of human PYDC1 produced in E.coli.
Affinity purified
Non-conjugated
IgG1
Product Properties
-
Appearance
Liquid
-
Formulation
Supplied in PBS, pH 7.4.
-
Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
-
Shipping
Shipping with blue ice.
Background
-
Function
PYDC1 associates with PYCARD/ASC and modulates its ability to collaborate with MEFV/pyrin and NLRP3/cryopyrin in NF-kappa-B and pro-caspase-1 activation. Suppresses kinase activity of NF-kappa-B inhibitor kinase (IKK) complex, expression of NF-kappa-B inducible genes and inhibits NF-kappa-B activation by cytokines and LPS
-
Subcellular Localization
Cytoplasm
-
Expression
Tissue_Specificity: Predominantly expressed in monocytes, macrophages and granulocytes -
Isoforms & Post-Translational Modification
Q8WXC3: 89 amino acids, molecular weight 10107 Da.
-
Subunit
Interacts with PYCARD/ASC (via pyrin domain)
-
SwissProt ID
-
Synonyms
ASC2; cPOP1; POP1; PYC1
Documentation
Powered by Bioz
