ASCC1 Antibody (YA8397)

Cat. No.: HY-P88713: Data Sheet User Guide for Antibodies
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ASCC1 Antibody (YA8397) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to ASCC1.

For research use only. We do not sell to patients.

Size		Stock
50 μL		Get quote
100 μL		Get quote

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WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Documentation

Description

ASCC1 Antibody (YA8397) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to ASCC1.

Host

Mouse

Clonality

Monoclonal

Molecular Weight

Predicted band size: 41 kDa

Species Reactivity

Human, Mouse, Rat

SwissProt ID

Q8N9N2

Immunogen

Full length human recombinant protein of human ASCC1 produced in HEK293T cell.

Application &
Dilution Ratio

Application	Dilution Ratio
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:150-500
ICC/IF ICC/IF: Immunocytochemistry/Immunofluorescence	1:100-250
FC FC: Flow Cytometry	1:100

Sensitivity	Endogenous	Purity	Affinity purified
Conjugation	Non-conjugated	Modification	Unmodified
Isotype	IgG1

Appearance

Liquid

Formulation

Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Background

Function：Plays a role in DNA damage repair as component of the ASCC complex (PubMed:29997253). Part of the ASC-1 complex that enhances NF-kappa-B, SRF and AP1 transactivation (PubMed:12077347). In cells responding to gastrin-activated paracrine signals, it is involved in the induction of SERPINB2 expression by gastrin. May also play a role in the development of neuromuscular junction

Subcellular Localization：Nucleus,Nucleus speckle

Expression：
Tissue_Specificity: Ubiquitous

Isoforms & Post-Translational Modification：Q8N9N2 has two isomers: Q8N9N2-1: 45509 Da (predicted); Q8N9N2-2: 41228 Da (predicted).

Subunit：Identified in the ASCC complex that contains ASCC1, ASCC2 and ASCC3 (PubMed:29144457, PubMed:29997253)

Synonyms

ASC1p50; CGI-18; RP11-150D20.4

Documentation

User Guide for Antibodies (1077 KB)