260 Results for "

Mer

" in MedChemExpress (MCE) Product Catalog:
Products (260)

260 Results for "Mer" in MCE Product Catalog:

Cat. No.: HY-P10635
CAS No.: 403668-80-4
Research Areas:  

Inflammation/Immunology

TKD (450-463) is a 14-mer peptide (TKDNNLLGRFELSG). TKD (450-463) is able to stimulate the cytolytic and proliferative activity of NK cells at concentrations equivalent to full-length Hsp70 protein .
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Cat. No.: HY-177636
CAS No.: 2857819-69-1
Target:  

HIV

Research Areas:  

Infection

GPI2A is a 20-mer antisense oligonucleotide sequence that is complementary to a region of the HIV-1 gag gene. GPI2A shows a significant inhibitory effect on p55 and its cleavage product p39/41.
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Cat. No.: HY-P11446A
Research Areas:  

Cancer

AE105 TFA is a 9-mer peptide probe targeting the urokinase-type plasminogen activator receptor (uPAR). AE105 TFA binds tightly to the uPA-binding cavity of uPAR. AE105 TFA can be used for the study of cancer .
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Cat. No.: HY-P4092
CAS No.: 386223-83-2
Target:  

Inhibitory Antibodies

Research Areas:  

Cancer

HN-1 is a 12-mer peptide with specific activity to head and neck squamous cell cancer (HNSCC) cells. HN-1, as a tumor-specific peptide, is capable of penetrating tumor tissues. HN-1 is capable of translocating agents across cell membranes .
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Cat. No.: HY-178438
CAS No.: 3062159-91-2
Target:  

c-Met/HGFR Apoptosis

Research Areas:  

Cancer

Mer/c-Met-IN-1 is a potent Mer/c-met dual inhibitor with IC50 values of 1 and 19 nM. Mer/c-Met-IN-1 can inhibit cancer cells proliferation, migration and induce apoptosis. Mer/c-Met-IN-1 can be used for the research of cancer, such as colon cancer .
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Cat. No.: HY-118633
CAS No.: 67-98-1
Synonyms: Mer-25
Target:  

Estrogen Receptor/ERR

Research Areas:  

Endocrinology

Ethamoxytriphetol (MER-25) is a nonsteroidal antiestrogen .
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Cat. No.: HY-160223
Target:  

STING

Research Areas:  

Infection Inflammation/Immunology

ssVACV-70mer sodium is a 70 bp single-stranded oligonucleotide containing viral DNA motifs that derive from the vaccinia virus DNA. Unlike its double-stranded counterpart dsVACV 70mer, ssVACV 70mer is not IFN-inducer .
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Cat. No.: HY-P9805
Synonyms: MerS-3A1; MerS Antibody-3A1

Target:  

SARS-CoV

Research Areas:  

Infection

Anti-MERS-3A1 mAb (MERS-3A1) is a human monoclonal IgG1 antibody with the high binding affinity produced in CHO cells. Anti-MERS-3A1 mAb bocks the binding of MERS-CoV spike protein to DPP4 receptor .
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Cat. No.: HY-P991445

Target:  

SARS-CoV

Research Areas:  

Infection

REGN3051 is a human IgG1 monoclonal antibody (mAb) targeting MERS CoV. REGN3051 reduces viral titers in the lungs of mice expressing human DPP4. REGN3051 decreases lung disease severity and viral replication in marmosets inoculated with MERS-CoV. Recommended isotype control: Human IgG1 kappa, Isotype Control (HY-P99001) .
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Cat. No.: HY-137985
CAS No.: 149598-70-9
Synonyms: Stachybotrydial; F 1839M; Stachybotrydial
Target:  

HSV Virus Protease

Research Areas:  

Infection

Mer-NF5003F (Stachybotrydial; F 1839M), a sesquiterpene isolated from Stachybotrys, inhibits avian medulloblastoma virus (AMV) protease (IC50=7.8 μM). Mer-NF5003F inhibits sialyltransferase 6N (ST6N), ST3O, and ST3N (IC50=0.61, 6.7, and 10 μg/mL, respectively), and fucosyltransferase (IC50=11.3 μg/mL). Mer-NF5003F has in vitro activity against herpes simplex virus HSV-1 (IC50=4.32 μg/mL) and multidrug-resistant Plasmodium falciparum K1 strain (IC50=0.85 μg/mL).
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Cat. No.: HY-153488A
Target:  

Ras

Research Areas:  

Cancer

ISIS-2503 sodium is a 20-mer antisense oligonucleotide that inhibits Ha-Ras expression
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Cat. No.: HY-P10442
Target:  

Inhibitory Antibodies

Research Areas:  

Others

Cinnamosyn is a 10-mer N-cinnamoyl-containing peptide that is cytotoxic to human cells .
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Cat. No.: HY-162674
CAS No.: 3049658-41-2
Target:  

SARS-CoV

Research Areas:  

Infection

MERS-CoV-IN-2 (compound 3c) is a MERS-CoV 3CLpro inhibitor (IC50=17nM). MERS-CoV-IN-2 inhibits the activity of the 3CLpro enzyme by binding to the active site of the enzyme, specifically the S4 subsite, thereby exhibiting antiviral activity against SARS-CoV-2 and MERS-CoV .
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Cat. No.: HY-177635
CAS No.: 2243120-19-4
Research Areas:  

Cancer

GNKG168 is a synthetic, 21-mer, unmethylated CpG oligodeoxynucleotide. It acts as a TLR9 agonist with immunostimulatory activity.
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Cat. No.: HY-177635A
Research Areas:  

Cancer

GNKG168 sodium is a synthetic, 21-mer, unmethylated CpG oligodeoxynucleotide. It acts as a TLR9 agonist with immunostimulatory activity.
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Cat. No.: HY-151990
Target:  

SARS-CoV

Research Areas:  

Infection

SARS-CoV-2/MERS Mpro-IN-1 (compound 9c) is a potent SARS-CoV-2 and MERS main protease inhibitor with IC50 values of 0.10, 0.06 µM, respectively .
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Cat. No.: HY-151991
CAS No.: 3034217-02-9
Target:  

SARS-CoV

Research Areas:  

Infection

SARS-CoV-2/MERS Mpro-IN-2 (compound 9d) is a potent SARS-CoV-2 and MERS main protease inhibitor with IC50 values of 0.21, 0.07 µM, respectively .
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Cat. No.: HY-P9804
Synonyms: MerS-2E6; MerS Antibody-2E6

Target:  

SARS-CoV

Research Areas:  

Infection

Anti-MERS-2E6 mAb (MERS-2E6; MERS Antibody-2E6), a human neutralizing antibody IgG1 (CHO expressed) that can compete for the binding of the virus Spike protein to the receptor (CD26), thereby inhibiting virus invasion into host cells.
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Cat. No.: HY-139150
CAS No.: 2088132-99-2
Research Areas:  

Cancer

EZH2-IN-4 is an orally active, potent EZH2 inhibitor with IC50s of 0.923 nM and 2.65 nM against wild type (WT) 5-membered (5-mer) EZH2 and mutant 5-mer EZH2, respectively. EZH2-IN-4 has anti-cancer activity .
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Cat. No.: HY-139908
CAS No.: 2245697-92-9
Purity:  99.53%
Target:  

SARS-CoV

Research Areas:  

Infection

MERS-CoV-IN-1 exhibits excellent inhibitory activity against coronavirus. MERS-CoV-IN-1 is useful as a pharmaceutical composition for preventing coronavirus-induced diseases (MERS-CoV and SARS) (extracted from patent WO2018174442A1, compound 1) .
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