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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
947 Results for "
sensitive
" in MedChemExpress (MCE) Product Catalog:
Products (947)
947 Results for "sensitive" in MCE Product Catalog:
製品番号: HY-P74216
純度: ≥ 95%, as determined by reducing SDS-PAGE.
別名: CTLA4; Celiac Disease 3; Prev. CELIAC3; Cytotoxic T Lymphocyte Associated Antigen 4 Short Spliced Form; Prev. IDDM12; Cytotoxic T-Lymphocyte-Associated Serine Esterase-4; CTLA-4; Cytotoxic T-Lymphocyte-Associated Protein 4; CD152; Cytotoxic T-Lymphocyte Antigen 4; Cytotoxic T-Lymphocyte Protein 4; Alternative Protein CTLA4; GSE; Celiac Disease; CD; CD152 Antigen; Cytotoxic T-Lymphocyte-Associated Antigen 4; ALPS5; Insulin-Dependent Diabetes Mellitus 12; GRD4; Gluten-sensitive Enteropathy; Cytotoxic T-Lymphocyte Associated Protein 4; Ligand And Transmembrane Spliced Cytotoxic T Lymphocyte Associated Antigen 4
Species:
Rat
Source:
HEK293
製品番号: HY-14604R
CAS 番号: 90494-79-4
別名: SR57746A (Standard); SR57746 hydrochloride (Standard)
研究分野:
Xaliproden (hydrochloride) (Standard) is the analytical standard of Xaliproden (hydrochloride). This product is intended for research and analytical applications. Xaliproden (SR57746) hydrochloride (SR57746A) is an orally active, highly selective 5-HT1A receptor agonist. Xaliproden hydrochloride activates pertussis toxin-sensitive G protein-coupled signaling cascades, as well as the PKC, ERK1/ERK2, Akt and p21 Ras/MEK-1 pathways. Xaliproden hydrochloride also downregulates the JNK/p66/c-Jun signaling pathway, induces phosphorylation of the shc adaptor protein, regulates extracellular dopamine and 5-HT levels, and induces [ 35S]GTPγS labeling in rat brain structures rich in 5-HT1A receptors. Xaliproden hydrochloride exerts neurotrophic, neuroprotective, renoprotective, anti-inflammatory, anti-apoptotic, anti-fibrotic and analgesic effects. Xaliproden hydrochloride also enhances NGF-induced neurite outgrowth, promotes motor neuron survival, attenuates renal tubular injury and inhibits chemotherapy-induced mechanical allodynia, without activating or altering NGF-induced TrkA receptor activation. Xaliproden hydrochloride can be used in the research of motor neuron disease, diabetic nephropathy, chemotherapy-induced peripheral neuropathy, amyotrophic lateral sclerosis, Alzheimer's disease, acute tonic nociceptive pain, inflammatory pain, depression and anxiety .
製品番号: HY-P704083
純度: ≥ 90%, as determined by reducing SDS-PAGE.
別名: UBE2V2; Ubiquitin Conjugating Enzyme E2 V2; Ubiquitin-Conjugating Enzyme E2 Variant 2; EDPF-1; EDAF-1; MMS2; UEV2; DDVit-1; DDVIT1; UEV-2; EDPF1; Enterocyte Differentiation-Associated Factor 1; Enterocyte Differentiation-Promoting Factor 1; Vitamin D3-Inducible Protein; MMS2 Homolog; DDVit 1; CDNA,FLJ93989,Homo Sapiens Ubiquitin-Conjugating Enzyme E2 Variant 2 (UBE2V2),MRNA; Methyl Methanesulfonate sensitive 2,S.Cerevisiae,Homolog Of; Ubiquitin-Conjugating Enzyme E2 Variant 2,Isoform CRA_a; Enterocyte Differentiation-Associated Factor EDAF-1; Enterocyte Differentiation Promoting Factor 1 Alpha,25-Dihydroxyvitamin D3-Inducible
Species:
Human
Source:
E. coli
製品番号: HY-P704084
純度: ≥ 90%, as determined by reducing SDS-PAGE.
別名: UBE2V2; Ubiquitin Conjugating Enzyme E2 V2; Ubiquitin-Conjugating Enzyme E2 Variant 2; EDPF-1; EDAF-1; MMS2; UEV2; DDVit-1; DDVIT1; UEV-2; EDPF1; Enterocyte Differentiation-Associated Factor 1; Enterocyte Differentiation-Promoting Factor 1; Vitamin D3-Inducible Protein; MMS2 Homolog; DDVit 1; CDNA,FLJ93989,Homo Sapiens Ubiquitin-Conjugating Enzyme E2 Variant 2 (UBE2V2),MRNA; Methyl Methanesulfonate sensitive 2,S.Cerevisiae,Homolog Of; Ubiquitin-Conjugating Enzyme E2 Variant 2,Isoform CRA_a; Enterocyte Differentiation-Associated Factor EDAF-1; Enterocyte Differentiation Promoting Factor 1 Alpha,25-Dihydroxyvitamin D3-Inducible
Species:
Human
Source:
Sf9 insect cells
製品番号: HY-D3103
CAS 番号: 1027058-07-6
Target:
研究分野:
CMTDP is a Fluorescent probe for detecting local polarity changes around the Cys34 domain of bovine serum albumin during pH-induced N→B conformational transition. It is a thiol-specific and polarity-sensitive probe; it covalently labels the free cysteine residue at position 34 (Cys34) of bovine serum albumin, and its fluorescence maximum emission wavelength shifts in response to solvent polarity, but not to pH and temperature. When labeled to BSA, as the local polarity around the Cys34 domain increases with rising pH, the probe shows a bathchromic shift in fluorescence emission wavelength and a decrease in fluorescence intensity, which allows quantification of the local polarity change via the relationship between emission wavelength shift and dielectric constant. CMTDP itself has absorption peaks at ~392 and 508 nm, and CMTDP-labeled BSA has excitation maxima at 376 and 470 nm at pH 6.0, with the shorter-wavelength excitation peak red-shifting as pH increases while the longer one remains stable; when excited at 470 nm, the fluorescence emission maximum shifts from 570 nm at pH 6.0 to 577 nm at pH 9.1, while free CMTDP at pH 7.4 has an emission maximum at 621 nm. The excitation/emission wavelengths for CMTDP-labeled BSA are Ex/Em = 376/570 nm at pH 6.0, Ex/Em = ~376+/573 nm at pH 7.4, Ex/Em = ~376+/575 nm at pH 8.0, Ex/Em = ~376+/577 nm at pH 9.1, and for free CMTDP at pH 7.4, Ex/Em (when excited at 470 nm) = 470/621 nm[1].
製品番号: HY-P704082
純度: ≥ 90%, as determined by reducing SDS-PAGE.
別名: UBE2V2; Ubiquitin Conjugating Enzyme E2 V2; Ubiquitin-Conjugating Enzyme E2 Variant 2; EDPF-1; EDAF-1; MMS2; UEV2; DDVit-1; DDVIT1; UEV-2; EDPF1; Enterocyte Differentiation-Associated Factor 1; Enterocyte Differentiation-Promoting Factor 1; Vitamin D3-Inducible Protein; MMS2 Homolog; DDVit 1; CDNA,FLJ93989,Homo Sapiens Ubiquitin-Conjugating Enzyme E2 Variant 2 (UBE2V2),MRNA; Methyl Methanesulfonate sensitive 2,S.Cerevisiae,Homolog Of; Ubiquitin-Conjugating Enzyme E2 Variant 2,Isoform CRA_a; Enterocyte Differentiation-Associated Factor EDAF-1; Enterocyte Differentiation Promoting Factor 1 Alpha,25-Dihydroxyvitamin D3-Inducible
Species:
Human
Source:
Sf9 insect cells
製品番号: HY-P86936
別名: KCD2 antibody; KCND 2 antibody; KCND2 antibody; KCND2_HUMAN antibody; KIAA1044 antibody; MGC119702 antibody; MGC119703 antibody; Potassium voltage gated channel Shal related subfamily member 2 antibody; Potassium voltage-gated channel subfamily D member 2 antibody; RK 5 antibody; KCD2 antibody; KCND 2 antibody; KCND2 antibody; KCND2_HUMAN antibody; KIAA1044 antibody; MGC119702 antibody; MGC119703 antibody; Potassium voltage gated channel Shal related subfamily member 2 antibody; Potassium voltage-gated channel subfamily D member 2 antibody; RK 5 antibody; RK5 antibody; Voltage gated potassium channel Kv4.2 antibody; Voltage gated potassium channel subunit Kv4.2 antibody; Voltage sensitive potassium channel antibody; Voltage-gated potassium channel subunit Kv4.2 antibody;
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
