Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
94 Results for "
HSC
" in MedChemExpress (MCE) Product Catalog:
Products (94)
94 Results for "HSC" in MCE Product Catalog:
Cat. No.: HY-P85433
Synonyms: ST13; AAG2; FAM10A1; HIP; SNC6; HSC70-interacting protein; Hip; Aging-associated protein 2; Progesterone receptor-associated p48 protein; Protein FAM10A1; Putative tumor suppressor ST13; Renal carcinoma antigen NY-REN-33; Suppression of tum
Cat. No.: HY-10941R
CAS No.: 1134156-31-2
Target:
Research Areas:
VER-155008 (Standard) is the analytical standard of VER-155008 (HY-10941). This product is intended for research and analytical applications. VER-155008 is an inhibitor of Hsp70, with IC50s of 0.5 μM, 2.6 μM, and 2.6 μM for Hsp70, Hsc70 and Grp7, respectively, and with a Kd of 0.3 μM for Hsp70.
Cat. No.: HY-P11549
CAS No.: 663933-94-6
Target:
Research Areas:
Cat. No.: HY-129389R
CAS No.: 3554-93-6
Research Areas:
Benzyl-α-GalNAc (Standard) is the analytical standard of Benzyl-α-GalNAc (HY-129389). This product is intended for research and analytical applications. Benzyl-α-GalNAc is a potent O-glycosylation inhibitor. Benzyl-α-GalNAc effectively inhibits the proliferation and activation of LX-2 cells and suppresses the expression of collagen I/III, which has good potential for investigation in liver fibrosis. Benzyl-α-GalNAc also significantly enhances the anti-tumour activity of 5-Fluorouracil (HY-90006) (e.g. pancreatic cancer) by inhibiting O-glycosylation .
Cat. No.: HY-P706175
Purity: ≥ 90%, as determined by SDS-PAGE.
Synonyms: FUT1; Fucosyltransferase 1 (Galactoside 2-Alpha-L-Fucosyltransferase); Prev. HSC; Truncated Alpha(1,2)Fucosyltransferase; Prev. H; A-1, 2 Fucosyltransferase (H Antigen); GDP-L-Fucose:Beta-D-Galactoside 2-Alpha-L-Fucosyltransferase 1; Nonfunctional Fucosyl
Species:
Virus
Source:
E. coli
Cat. No.: HY-180765
Target:
Research Areas:
Colchicine-O-CO-Enyl(Me)-Enyl-Enyl(Me)-Enyl-1,3,3-trimethylcyclohex-1-ene (compound L2) is a lipophilic colchicinoid formulation targeting hepatic stellate cells (HSC). Colchicine-O-CO-Enyl(Me)-Enyl-Enyl(Me)-Enyl-1,3,3-trimethylcyclohex-1-ene increases the levels of MMP2, MMP8 and MMP9, demonstrating the protective effect in tissue remodeling. Colchicine-O-CO-Enyl(Me)-Enyl-Enyl(Me)-Enyl-1,3,3-trimethylcyclohex-1-ene exhibits anti-fibrotic activity in CCL4-induced liver fibrosis (LF) mouse model. Colchicine-O-CO-Enyl(Me)-Enyl-Enyl(Me)-Enyl-1,3,3-trimethylcyclohex-1-ene can be used for LF research .
Cat. No.: HY-186305
CAS No.: 3078747-38-0
VL-422 derivative is an ionizable lipid component of targeted lipid nanoparticles. VL-422 derivative formulated with a helper lipid, cholesterol, and a PEGylated lipid forms lipid nanoparticles (LNPs). VL-422 derivative can be used for in vivo or ex vivo delivery of agents to immune cells .
Cat. No.: HY-N17771
CAS No.: 1987871-73-7
Target:
Cat. No.: HY-182038
Target:
Research Areas:
TGF-β1/Smad3-IN-2 is an orally active antifibrotic agent. TGF-β1/Smad3-IN-2 has high affinity for VDR and can inhibit the TGFβ/SMAD3 signaling pathway. TGF-β1/Smad3-IN-2 inhibits hepatic stellate cell activation, reduces extracellular matrix deposition, and alleviates liver fibrosis in a bile duct ligation mouse model. TGF-β1/Smad3-IN-2 can be used for the research of liver fibrosis .
Cat. No.: HY-P992333
Research Areas:
Cat. No.: HY-N16980
CAS No.: 2292113-33-6
Target:
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
