2. Immunology/Inflammation
  3. C-type Lectin-like Receptors (CTLRs)
  4. CLT030 Antibody

CLT030 Antibody is a human monoclonal antibody targeting CLL1/CLEC12A/CD371, with a Kd value of 7.32 nM against human targets. CLT030 Antibody can be used to synthesize the ADC CLT030. It is applicable to research related to acute myeloid leukemia.

For research use only. We do not sell to patients.

CLT030 Antibody

CLT030 Antibody Chemical Structure

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CLT030 Antibody Related Antibodies

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Description

CLT030 Antibody is a human monoclonal antibody targeting CLL1/CLEC12A/CD371, with a Kd value of 7.32 nM against human targets. CLT030 Antibody can be used to synthesize the ADC CLT030. It is applicable to research related to acute myeloid leukemia[1].

Species Reactivity

Human
IC50 & Target[1]

CLL1

7.32 nM (Kd)

In Vitro

CLT030 Antibody can be used to synthesize ADC CLT030, a CLL1 antibody-drug conjugate targeting leukemia stem cells, which is applied to research on acute myeloid leukemia[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

CLT030 Antibody Related Antibodies
Gene ID

160364  [NCBI]

Accession
Target

CLEC12A/CD371
Application

ELISA, FACS, Functional assay
Conjugated

Unconjugated
Reconsititution

The product can be reconstituted/diluted with sterile PBS or saline.
Formulation

Please refer to the lot-specific COA for specific buffer information.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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CLT030 Antibody Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

CLT030 AntibodyC-type Lectin-like Receptors (CTLRs)acute myeloid leukemialeukemic stem cellsCLL1HL60OCI-AML2NOD/SCID micehuman AML cell linesnormal human CD34+ HSCsCB-17/Scid Beige miceprimary human AML patient cellsInhibitorinhibitorinhibit

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CLT030 Antibody
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