![Mal((3S,3aR,6S,6aR)-Hexahydrofuro[3,2-b]furan-3,6-diamine-PEG12)-β-Glu-PAB-Exatecan](https://file.medchemexpress.com/product_pic/hy-173634.gif "Click to View Mal((3S,3aR,6S,6aR)-Hexahydrofuro[3,2-b]furan-3,6-diamine-PEG12)-β-Glu-PAB-Exatecan Product Detail")
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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
150 Results for "
LP
" in MedChemExpress (MCE) Product Catalog:
Products (150)
150 Results for "LP" in MCE Product Catalog:
Cat. No.: HY-185729
Synonyms: ADCT-401
Target:
Research Areas:
MEDI3726 (ADCT-401) is a prostate-specific membrane antigen (PSMA)-targeting antibody-drug conjugate (ADC), composed of LP Tesirine (HY-128952) and antibody J591 (HY-P991359). MEDI3726 binds PSMA’s extracellular domain, triggers endocytosis, undergoes lysosomal degradation to release a pyrrolobenzodiazepine warhead. MEDI3726 induces DNA crosslinking, DNA damage, cell death, cytotoxicity, and inhibits tumor growth in mouse xenograft models. MEDI3726 undergoes in vivo catabolism primarily via heavy-light chain dissociation, with minimal warhead deconjugation. MEDI3726 can be used for the research of metastatic castration-resistant prostate cancer and prostate cancers .
Cat. No.: HY-173634
CAS No.: 3059991-66-8
Research Areas:
Mal((3S,3aR,6S,6aR)-Hexahydrofuro[3,2-b]furan-3,6-diamine-PEG12)-β-Glu-PAB-Exatecan (LP1) is a drug-linker conjugate composed of a potent a DNA Topoisomerase I inhibitor Exatecan (HY-13631) and a linker Mal((3S,3aR,6S,6aR)-Hexahydrofuro[3,2-b]furan-3,6-diamine-PEG12)-β-Glu-PAB (HY-173635) to make antibody agent conjugate (ADC), AZD0516 (HY-173639) .
Cat. No.: HY-P76581
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: RPLP1; P1; Ribosomal Protein Lateral Stalk Subunit P1; Ribosomal Protein, Large, P1; Large Ribosomal Subunit Protein P1; Acidic Ribosomal Phosphoprotein P1; 60S Acidic Ribosomal Protein P1; RPP1; LP1; RRP1
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-P75461
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CALM2; LP7057 Protein; Calmodulin 2; Calmodulin-1; PHKD2; Calmodulin-3; CAMII; CALML2; PHKD; CAMIII; Calmodulin 2 (Phosphorylase Kinase, Delta); LQT15; Phosphorylase Kinase Subunit Delta 2; CALM3; Phosphorylase Kinase Subunit Delta; CALM1; Prepro-Calmodul
Species:
Human
Source:
E. coli
Cat. No.: HY-P77444
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: PLA2G7; LDL-Associated Phospholipase A2; Phospholipase A2 Group VII; Group-VIIA Phospholipase A2; PAFAH; PAF 2-Acylhydrolase; LDL-PLA2; PAF Acetylhydrolase; LP-PLA2; LDL-PLA(2); Phospholipase A2, Group VII (Platelet-Activating Factor Acetylhydrolase, Plas
Species:
Mouse
Source:
HEK293
Cat. No.: HY-P700567
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: PLA2G7; LDL-Associated Phospholipase A2; Phospholipase A2 Group VII; Group-VIIA Phospholipase A2; PAFAH; PAF 2-Acylhydrolase; LDL-PLA2; PAF Acetylhydrolase; LP-PLA2; LDL-PLA(2); Phospholipase A2, Group VII (Platelet-Activating Factor Acetylhydrolase, Plas
Species:
Mouse
Source:
Sf9 insect cells
Cat. No.: HY-P700568
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: PLA2G7; LDL-Associated Phospholipase A2; Phospholipase A2 Group VII; Group-VIIA Phospholipase A2; PAFAH; PAF 2-Acylhydrolase; LDL-PLA2; PAF Acetylhydrolase; LP-PLA2; LDL-PLA(2); Phospholipase A2, Group VII (Platelet-Activating Factor Acetylhydrolase, Plas
Species:
Mouse
Source:
HEK293
Cat. No.: HY-P78778
Purity: ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: CLEC4G; LSECtin; C-Type Lectin Domain Family 4 Member G; C-Type Lectin Domain Family 4, Member G; LSECTIN; CLEC4G Protein; UNQ431; DTTR431; Liver And Lymph Node Sinusoidal Endothelial Cell C-Type Lectin; LP2698; C-Type Lectin Superfamily 4, Member G
Species:
Human
Source:
HEK293
Cat. No.: HY-P702771
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: RPLP0; LP0; Ribosomal Protein Lateral Stalk Subunit P0; P0; Large Ribosomal Subunit Protein UL10; Neutral Ribosomal Phosphoprotein P0; 60S Acidic Ribosomal Protein P0; Ribosomal Protein, Large, P0; PRLP0; 60S Ribosomal Protein L10E; L10E; Acidic Ribosomal
Species:
Mouse
Source:
E. coli
Cat. No.: HY-P70993
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: PLA2G7; LDL-Associated Phospholipase A2; Phospholipase A2 Group VII; Group-VIIA Phospholipase A2; PAFAH; PAF 2-Acylhydrolase; LDL-PLA2; PAF Acetylhydrolase; LP-PLA2; LDL-PLA(2); Phospholipase A2, Group VII (Platelet-Activating Factor Acetylhydrolase, Plasma); GVIIA-PLA2; 1-Alkyl-2-Acetylglycerophosphocholine Esterase; Lipoprotein-Associated Phospholipase A2; 2-Acetyl-1-Alkylglycerophosphocholine Esterase; PAFAD; Platelet-Activating Factor Acetylhydrolase
Species:
Human
Source:
HEK293
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
