179 Results for "

β-D-glucuronide

" in MedChemExpress (MCE) Product Catalog:
Products (179)

179 Results for "β-D-glucuronide" in MCE Product Catalog:

62
62 Publications Verification
Cat. No.: HY-N0197
CAS No.: 21967-41-9
Synonyms: Baicalein 7-O-β-D-glucuronide
Baicalin, as a flavonoid glycoside, is an allosteric carnitine palmityl transferase 1 (CPT1) activator. Baicalin reduces the expression of NF-κB .
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5
5 Cited Publications
Cat. No.: HY-N7176
CAS No.: 22688-78-4
Synonyms: Kaempferol-3-glucuronide; Kaempferol-3-O-glucuronide
Kaempferol 3-O-β-D-glucuronide (Kaempferol-3-glucuronide) is a metabolite of kaempferol that can be taken orally and has anti-inflammatory properties. Kaempferol 3-O-β-D-glucuronide can activate AKT/GSK3β phosphorylation and improve glucose metabolism .
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2
2 Cited Publications
Cat. No.: HY-135391
CAS No.: 190448-57-8
Purity:  99.77%
Synonyms: Ezetimibe glucuronide; Ezetimibe β-D-glucuronide
Target:  

Drug Metabolite

Research Areas:  

Metabolic Disease

Ezetimibe phenoxy glucuronide (Ezetimibe glucuronide) is the active metabolite of Ezetimibe. Antihyperlipoproteinemic activity . Ezetimibe is a potent cholesterol absorption inhibitor .
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2
2 Cited Publications
Cat. No.: HY-B0947
CAS No.: 122-16-7
Research Areas:  

Infection

Sulfanitran is an antibacterial and anticoccidial agent used in poultry feeds. Sulfanitran also is a multidrug resistance protein 2 (MRP2) stimulator that can increase the affinity of MRP2 for estradiol-17-β-D-glucuronide (E217βG) .
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1
1 Cited Publications
Cat. No.: HY-D0935A
CAS No.: 881005-91-0
Synonyms: MUG
4-Methylumbelliferyl-β-D-glucuronide hydrate is a fluorogenic substrat (λex=362 nm, λem=445 nm). 4-Methylumbelliferyl-β-D-glucuronide hydrate has potential applications in detecting the activity of β-glucuronidase and the number of Escherichia coli .
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1
1 Cited Publications
Cat. No.: HY-W039892
CAS No.: 10344-94-2
Synonyms: pNPG_1
Target:  

β-glucuronidase

Research Areas:  

Others

4-Nitrophenyl β-D-glucuronide (pNPG_1) is aderivative of 4-Nitrophenol. 4-Nitrophenyl β-D-glucuronide is the chromogenic substrate for β-glucuronidase .
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1
1 Cited Publications
Cat. No.: HY-D0935
CAS No.: 6160-80-1
4-Methylumbelliferyl-β-D-glucuronide is a fluorogenic substrat (λex=362 nm, λem=445 nm). 4-Methylumbelliferyl-β-D-glucuronide has potential applications in detecting the activity of β-glucuronidase and the number of Escherichia coli .
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1
1 Cited Publications
Cat. No.: HY-N4099
CAS No.: 53527-42-7
Luteolin-3-O-beta-D-glucuronide, a glucuronide derivative of Luteolin (HY-N0162), is found in the leaves of Rosmarinus officinalis L. Luteolin-3-O-beta-D-glucuronide inhibits nitrite production in macrophages and binds strongly to FYN kinase .
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1
1 Cited Publications
Cat. No.: HY-N6879
CAS No.: 35110-20-4
DiosMetin 7-O-β-D-Glucuronide is an antioxidant constituent in the fruits of Luffa cylindrical .
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1
1 Cited Publications
Cat. No.: HY-N2481
CAS No.: 36948-76-2
Synonyms: Oroxyloside; Oroxylin A-7-O-β-D-glucuronide
Oroxylin A-7-O-glucuronide (oroxyloside) is an orally active flavonoid glucuronide and metabolite of Oroxylin A (HY-N0560). Oroxylin A-7-O-glucuronide can be extracted from the dried root of Scutellaria baicalensis. Oroxylin A-7-O-glucuronide exhibits prolyl oligopeptidase inhibitory activity. Oroxylin A-7-O-glucuronide inhibits the JNK pathway, upregulates PPARγ, and inhibits NF-κB p65 nuclear translocation. Oroxylin A-7-O-glucuronide reduces cytokine (IL-1β, IL-6) production. Oroxylin A-7-O-glucuronide exhibits anti-angiogenic, anti-tumor (glioma, liver cancer), anti-inflammatory, and hepatoprotective activities .
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Cat. No.: HY-136329
CAS No.: 894095-98-8
Purity:  99.44%
Target:  

ADC Linkers

Research Areas:  

Cancer

β-D-glucuronide-pNP-carbonate is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
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Cat. No.: HY-137522
CAS No.: 133525-01-6
Purity:  99.05%
Synonyms: 3'-Azido-3'-deoxythymidine β-D-glucuronide sodium
Target:  

Drug Metabolite

Research Areas:  

Others

Zidovudine O-β-D-glucuronide (3'-Azido-3'-deoxythymidine β-D-glucuronide) sodium is the glucuronide conjugate and metabolite of Zidovudine (HY-17413), which can be used to detect UGT2B7 activity. As a substrate, Zidovudine O-β-D-glucuronide sodium undergoes deconjugation via hydrolysis by immobilized β-glucuronidase to produce Zidovudine .
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Cat. No.: HY-138795
CAS No.: 227466-72-0
Purity:  98.00%
Target:  

Endogenous Metabolite

Research Areas:  

Cancer

Curcumin-β-D-glucuronide is a major metabolite after oral intake of Curcumin in hepatic tissue and portal blood. Curcumin-β-D-glucuronide can be used for the research of colon cancer .
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Cat. No.: HY-129987
CAS No.: 15087-02-2
Purity:  99.46%
Estradiol 17-(β-D-Glucuronide) sodium is a D-ring glucuronide metabolite of natural estrogen formed in the liver. Estradiol 17-(β-D-Glucuronide) sodium is a substrate of the organic anion-transporting polypeptide family (Oatp) and multidrug resistance-associated protein 2 (Mrp2). Estradiol 17-(β-D-Glucuronide) sodium regulates MRP8-mediated transport processes and inhibits MRP8-mediated transport of dehydroepiandrosterone 3-sulfate and taurocholic acid. Estradiol 17-(β-D-Glucuronide) sodium induces immediate, reversible reduction of bile flow and acute intrahepatic cholestasis in female rats without altering the bile acid composition in bile. Estradiol 17-(β-D-Glucuronide) sodium can be used in studies related to intrahepatic cholestasis .
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Cat. No.: HY-W353102
CAS No.: 1806-98-0
Estradiol 17-(β-D-Glucuronide) is a D-ring glucuronide metabolite of natural estrogen formed in the liver. Estradiol 17-(β-D-Glucuronide) is a substrate of the organic anion-transporting polypeptide family (Oatp) and multidrug resistance-associated protein 2 (Mrp2). Estradiol 17-(β-D-Glucuronide) regulates MRP8-mediated transport processes and inhibits MRP8-mediated transport of dehydroepiandrosterone 3-sulfate and taurocholic acid. Estradiol 17-(β-D-Glucuronide) induces immediate, reversible reduction of bile flow and acute intrahepatic cholestasis in female rats without altering the bile acid composition in bile. Estradiol 17-(β-D-Glucuronide) can be used in studies related to intrahepatic cholestasis .
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Cat. No.: HY-137967
CAS No.: 38482-81-4
Purity:  ≥98.0%
Synonyms: Genistein 7-O-glucuronide
Target:  

Drug Metabolite

Research Areas:  

Metabolic Disease

Genistein 7-β-D-Glucuronide (Genistein 7-O-glucuronide) is the primary phase II metabolite of Genistein (HY-14596) in human and rat hepatocytes. Genistein 7-β-D-Glucuronide undergoes distinct deconjugation in different functional assays. Genistein 7-β-D-Glucuronide is produced via hepatic microsomal glucuronidation and shows a mild age-related increase in intrinsic clearance in male F344 rats. Genistein 7-β-D-Glucuronide can be used for research on metabolism .
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Cat. No.: HY-137959
CAS No.: 250780-40-6
Telmisartan acyl-β-D-glucuronide is an acyl-β-D-glucuronide and a metabolite of Telmisartan (HY-13955). Telmisartan acyl-β-D-glucuronide can be converted back to Telmisartan upon incubation with Glucuronidase. Partial acyl migration of Telmisartan acyl-β-D-glucuronide occurs under physiological conditions .
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Cat. No.: HY-148225
CAS No.: 261506-27-8
Purity:  94.79%
Target:  

Drug Metabolite

Research Areas:  

Cancer

Fulvestrant 3-β-D-Glucuronide, a metabolite, is glucuronide and sulfate conjugates of Fulvestrant (HY-13636), a pure anti-estrogenic steroid. Fulvestrant 3-β-D-Glucuronide can be used for the research of breast cancer .
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Cat. No.: HY-W699225
CAS No.: 154717-05-2
1-Hydroxypyrene β-D-glucuronide is a biochemical reagent.
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Cat. No.: HY-118774
CAS No.: 114991-26-3
Purity:  99.55%
Propofol β-D-glucuronide is a metabolite of Propofol sulfate and can be used for diagnosis to distinguish colorectal cancer from healthy individuals .
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