22688-78-4
Chemical Structure
Kaempferol 3-O-β-D-glucuronide
Synonym(s): Kaempferol-3-glucuronide; Kaempferol-3-O-glucuronide
- CAS No.: 22688-78-4
- Formula:C21H18O12
- Molecular Weight:462.36
IUPAC Name: (2S,3S,4S,5R,6S)-6-((5,7-dihydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-chromen-3-yl)oxy)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylic acid
InChIKey: FNTJVYCFNVUBOL-ZUGPOPFOSA-N
SMILES: O[C@H]([C@H]([C@@H]([C@@H](C(O)=O)O1)O)O)[C@@H]1OC2=C(C3=CC=C(O)C=C3)OC4=CC(O)=CC(O)=C4C2=O
Biological Activity: Kaempferol 3-O-β-D-glucuronide (Kaempferol-3-glucuronide) is a metabolite of kaempferol that can be taken orally and has anti-inflammatory properties. Kaempferol 3-O-β-D-glucuronide can activate AKT/GSK3β phosphorylation and improve glucose metabolism[1][2][3].
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Kaempferol 3-O-β-D-glucuronide | 99.47% | Kaempferol 3-O-β-D-glucuronide (Kaempferol-3-glucuronide) is a metabolite of kaempferol that can be taken orally and has anti-inflammatory properties. Kaempferol 3-O-β-D-glucuronide can activate AKT/GSK3β phosphorylation and improve glucose metabolism. | ||||||||||||||||||||
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Kaempferol 3-O-β-D-glucuronide (Standard) | ≥98% | Prosulfocarb (Standard) is the analytical standard of Prosulfocarb. This product is intended for research and analytical applications. Prosulfocarb is a herbicide with a rapidly growing use trend. Prosulfocarb is used in winter cereals to help address the problem of increasing biotic resistance of weeds to certain pesticides. Environmental and food effects of prosulfocarb have been observed, and its transfer pattern from target crops to non-target areas has been studied. The volatility effect of prosulfocarb is an important factor explaining the inefficiency of isolated area contamination and marginal protection against residue spread. | ||||||||||||||||||||
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- [1]. Khajuria V, et al. Kaempferol-3-o-β-d-glucuronate exhibit potential anti-inflammatory effect in LPS stimulated RAW 264.7 cells and mice model. Int Immunopharmacol. 2018;57:62-71. [Content Brief]
- [2]. Rupayan Bhattacharjee, et al. Extraction and Characterization of Flavonoid Kaempferol-3-Glucuronide from Mango for Treatment of Different Types of Cancers. Great Britain Journals Press. Print ISSN: 2631-8490
- [3]. Ge Fang, et al. The glucuronide metabolites of kaempferol and quercetin, targeting to the AKT PH domain, activate AKT/GSK3β signaling pathway and improve glucose metabolism. Journal of Functional Foods. Volume 82, July 2021, 104501.