4-Methylumbelliferyl-β-D-glucuronide
Based on 1 publication(s) in Google Scholar
4-Methylumbelliferyl-β-D-glucuronide is a fluorogenic substrat (λex=362 nm, λem=445 nm). 4-Methylumbelliferyl-β-D-glucuronide has potential applications in detecting the activity of β-glucuronidase and the number of Escherichia coli.
For research use only. We do not sell to patients.
- Purity: 99.93%
- CAS No.: 6160-80-1
- Formula: C16H16O9
- Molecular Weight:352.29
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Storage:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Publications Citing Use of MedChemExpress (MCE) 4-Methylumbelliferyl-β-D-glucuronide
More
Biological Activity
4-Methylumbelliferyl-β-D-glucuronide (156 µM-5 mM; 30 min) releases 4-methylumbelliferone at 37°C for enzymatic reactions[2].
4-Methylumbelliferyl-β-D-glucuronide (50 µg/mL; 24 h) is used to detect the number of Escherichia coli in TSA medium[3].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 6160-80-1
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Appearance Solid
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Molecular Weight 352.29
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Formula C16H16O9
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Color White to off-white
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SMILES
O[C@H]([C@H]([C@@H]([C@@H](C(O)=O)O1)O)O)[C@@H]1OC2=CC=C(C(O3)=C2)C(C)=CC3=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Publications (1)
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Journal Impact Factor
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Most Recent
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Neurobiol Dis
A novel mouse model of chronic neuronopathic Gaucher disease exhibits Parkinson's disease-like phenotypes. [Abstract]2025 Apr 5:106899. PMID: 40194636
Solvent & Solubility
DMSO : 100 mg/mL (283.86 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (275 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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Handling Instructions (2659 KB)
References
[1]. George I, et al. Use of beta-D-galactosidase and beta-D-glucuronidase activities for quantitative detection of totaland fecal coliforms in wastewater. Can J Microbiol. 2001 Jul;47(7):670-5. [Content Brief]
[2]. Sperker B, et al. High-performance liquid chromatographic quantification of 4-methylumbelliferyl-beta-D-glucuronide as a probe for human beta-glucuronidase activity in tissue homogenates. J Chromatogr B Biomed Appl. 1996 Oct 11;685(1):181-4. [Content Brief]
[3]. Villari P, et al. An evaluation of the use of 4-methylumbelliferyl-beta-D-glucuronide (MUG) in different solid media for the detection and enumeration of Escherichia coli in foods. Lett Appl Microbiol. 1997 Apr;24(4):286-90. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.8386 mL | 14.1929 mL | 28.3857 mL | 70.9643 mL |
| 5 mM | 0.5677 mL | 2.8386 mL | 5.6771 mL | 14.1929 mL | |
| 10 mM | 0.2839 mL | 1.4193 mL | 2.8386 mL | 7.0964 mL | |
| 15 mM | 0.1892 mL | 0.9462 mL | 1.8924 mL | 4.7310 mL | |
| 20 mM | 0.1419 mL | 0.7096 mL | 1.4193 mL | 3.5482 mL | |
| 25 mM | 0.1135 mL | 0.5677 mL | 1.1354 mL | 2.8386 mL | |
| 30 mM | 0.0946 mL | 0.4731 mL | 0.9462 mL | 2.3655 mL | |
| 40 mM | 0.0710 mL | 0.3548 mL | 0.7096 mL | 1.7741 mL | |
| 50 mM | 0.0568 mL | 0.2839 mL | 0.5677 mL | 1.4193 mL | |
| 60 mM | 0.0473 mL | 0.2365 mL | 0.4731 mL | 1.1827 mL | |
| 80 mM | 0.0355 mL | 0.1774 mL | 0.3548 mL | 0.8871 mL | |
| 100 mM | 0.0284 mL | 0.1419 mL | 0.2839 mL | 0.7096 mL |
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