227466-72-0
227466-72-0
Chemical Structure
Curcumin-β-D-glucuronide
- CAS No.: 227466-72-0
- Formula:C27H28O12
- Molecular Weight:544.50
IUPAC Name: (2S,3S,4S,5R,6S)-3,4,5-trihydroxy-6-(4-((1E,6E)-7-(4-hydroxy-3-methoxyphenyl)-3,5-dioxohepta-1,6-dien-1-yl)-2-methoxyphenoxy)tetrahydro-2H-pyran-2-carboxylic acid
InChIKey: BNSAVBGHRVFVNN-XSCLDSQRSA-N
SMILES: COC(C=C(C=C1)/C=C/C(CC(/C=C/C2=CC(OC)=C(C=C2)O)=O)=O)=C1O[C@@H]3O[C@@H]([C@H]([C@@H]([C@H]3O)O)O)C(O)=O
Biological Activity: Curcumin-β-D-glucuronide is a major metabolite after oral intake of Curcumin in hepatic tissue and portal blood. Curcumin-β-D-glucuronide can be used for the research of colon cancer[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
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Curcumin-β-D-glucuronide | 98.01% | Curcumin-β-D-glucuronide is a major metabolite after oral intake of Curcumin in hepatic tissue and portal blood. Curcumin-β-D-glucuronide can be used for the research of colon cancer. | ||||||||||||||||||||
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References
- [1]. Ozawa-Umeta H, et, al. Curcumin β-D-glucuronide exhibits anti-tumor effects on oxaliplatin-resistant colon cancer with less toxicity in vivo. Cancer Sci. 2020 May;111(5):1785-1793. [Content Brief]
- [2]. Ozawa H, et, al. Curcumin β-D-Glucuronide Plays an Important Role to Keep High Levels of Free-Form Curcumin in the Blood. Biol Pharm Bull. 2017;40(9):1515-1524. [Content Brief]
