Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
9 Results for "
β-lactam ring
" in MedChemExpress (MCE) Product Catalog:
Products (9)
9 Results for "β-lactam ring" in MCE Product Catalog:
2
2 Cited Publications
Target:
Research Areas:
Nitrocefin is a highly activated, chromogenic cephalosporin derivative. Nitrocefin is a chromogenic β-lactamase substrate. Nitrocefin undergoes a distinctive color change from yellow to red as the amide bond in the β-lactam ring is hydrolyzed by β-lactamase. Nitrocefin is used in competitive inhibition studies in developmental work on β-lactamase-resistant antibiotics .
Target:
Research Areas:
Desfuroylceftiofur is an antibacterial agent and the active metabolite of Ceftiofur sodium (HY-B0898) with an intact β-lactam ring. Desfuroylceftiofur exhibits inhibitory activity against Gram-negative and Gram-positive pathogenic bacteria of veterinary interest in vitro. Desfuroylceftiofur can be used in the research of bovine respiratory disease, porcine respiratory disease, equine lymphadenitis, bovine mastitis, turkey colibacillosis, suppurative arthritis and respiratory infections .
Cat. No.: HY-108913R
CAS No.: 41906-86-9
Research Areas:
Nitrocefin (Standard) is the analytical standard of Nitrocefin. This product is intended for research and analytical applications. Nitrocefin is a chromogenic β-lactamase substrate that undergoes a distinctive color change from yellow to red as the amide bond in the β-lactam ring is hydrolyzed by β-lactamase. Nitrocefin is used in competitive inhibition studies in developmental work on β-lactamase-resistant antibiotics .
Cat. No.: HY-162094
CAS No.: 3027135-80-1
Target:
Research Areas:
CMX410 is an orally active and selective Mycobacterium tuberculosis Pks13 acyltransferase domain inhibitor and anti-bacterial agent. CMX410 reacts with the catalytic serine of the Pks13-AT domain to form a stable β-lactam ring, disables the enzyme’s active site, reduces trehalose monomycolate and trehalose dimycolate levels, triggers cell lysis, and reduces intracellular bacterial burden. CMX410 can be used for the research of tuberculosis .
Cat. No.: HY-121120
CAS No.: 77900-75-5
Category:
Target:
Cat. No.: HY-133841
CAS No.: 32746-94-4
Synonyms: Ampicillin impurity D
Target:
Research Areas:
Ampicilloic acid (Ampicillin impurity D) is a hydrolytic metabolite of the penicillin antibiotic Ampicillin (HY-B0522), produced by Alcanivorax sp. via β-lactamase-mediated β-lactam ring opening reaction .
Cat. No.: HY-P2998B
Target:
Research Areas:
β-Lactamase Blend (EC 3.5.2.6) inactivates β-lactam antibiotics by breaking open the β-lactam ring.
Cat. No.: HY-P2998A
Target:
Research Areas:
β-Lactamase, Pseudomonas aeruginosa (EC 3.5.2.6) inactivates β-lactam antibiotics by breaking open the β-lactam ring.
Cat. No.: HY-P2998C
Target:
Research Areas:
β-Lactamase, Enterobacter cloacae (EC 3.5.2.6) inactivates β-lactam antibiotics by breaking open the β-lactam ring.
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
