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Results for "

15-PGDH

" in MedChemExpress (MCE) Product Catalog:

16

Inhibitors & Agonists

1

Peptides

3

Recombinant Proteins

3

Antibodies

2

Oligonucleotides

Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-16968
    SW033291
    5+ Cited Publications

    		 15-PGDH Others
    SW033291 is a potent and high-affinity inhibitor of 15-PGDH with a Ki of 0.1 nM. SW033291 increases prostaglandin PGE2 levels in bone marrow and other tissues. SW033291 also promotes tissue regeneration .
    SW033291
  • HY-174990
    HW201877

    		15-PGDH Metabolic Disease Inflammation/Immunology
    HW201877 is a potent and orally active 15-prostaglandin dehydrogenase (15-PGDH) inhibitor with an IC50 of 3.6 nM. HW201877 demonstrates robust cellular efficacy in elevating PGE2 levels in A549 cells and exhibits remarkable efficacy in animal models of tissue injury and fibrosis. HW201877 can be used for the study of inflammatory bowel disease (IBD), idiopathic pulmonary fibrosis (IPF) and Crohn’s disease (CD) .
    HW201877
  • HY-176803
    MF-DH-300

    		15-PGDH Neurological Disease
    MF-DH-300 is a 15-PGDH inhibitor that can be applicable to the research of muscle disorders such as spinal muscular atrophy (SMA).
    MF-DH-300
  • HY-151807
    15-PGDH-IN-1

    		15-PGDH Metabolic Disease
    15-PGDH-IN-1 is a potent and orally active 15-PGDH inhibitior. 15-PGDH-IN-1 has inhibition activity against recombinant human 15-PGDH with an IC50 value of 3 nM. 15-PGDH-IN-1 can be used for the research of tissue repair and regeneration .
    15-PGDH-IN-1
  • HY-123548
    ML148

    		15-PGDH Inflammation/Immunology
    ML148 is a potent and selective 15-PGDH inhibitor with an IC50 of 56 nM. ML148 has the potential for the research of prostaglandin-signaling pathways .
    ML148
  • HY-117723
    MF-PGDH-008

    		15-PGDH Others
    MF-PGDH-008 serves as an inhibitor of human NAD(+)-dependent 15-hydroxyprostaglandin dehydrogenase (15-PGDH) .
    MF-PGDH-008
  • HY-178113
    15-PGDH-IN-4

    		15-PGDH Inflammation/Immunology
    15-PGDH-IN-4 (Compound 40) is a 15-PGDH inhibitor with an IC50 of 1.2 nM against h15-PGDH. 15-PGDH-IN-4 functionally inhibits the activity of 15-PGDH. 15-PGDH-IN-4 can be used in the research of colitis .
    15-PGDH-IN-4
  • HY-124230
    15-PGDH-IN-3

    		15-PGDH Metabolic Disease
    15-PGDH-IN-3 (Compound 61) is a selective competitive inhibitor of 15-hydroxyprostaglandin dehydrogenase (15-PGDH) .
    15-PGDH-IN-3
  • HY-119973
    CAY10397

    		15-PGDH Inflammation/Immunology
    CAY10397 is a selective and orally active 15-hydroxyprostaglandin dehydrogenase (15-PGDH) inhibitor. CAY10397 can inhibit 15-PGDH-dependent endogenous metabolite production. CAY10397 blocks the selenium-dependent protective in inflammation. CAY10397 can be used for the research of colitis .
    CAY10397
  • HY-116198
    15-PGDH-IN-2

    		15-PGDH Metabolic Disease
    15-PGDH-IN-2 (Compound 2) is a 15-PGDH inhibitor with an IC50 value of 0.274 nM. 15-PGDH-IN-2 can be used in research on hair loss, bone formation, gastric ulcer healing, and dermal wound healing .
    15-PGDH-IN-2
  • HY-P10457
    15-Hydroxy prostaglandin dehydrogenase blocking peptide

    15-PGDH (92-105)

    		 15-PGDH Others
    5-Hydroxy prostaglandin dehydrogenase blocking peptide (15-PGDH (92-105)) is a blocking peptide that corresponds to the amino acids (AGVNNEKNWEKTLQ) located at positions 92-105 of the 15-hydroxy prostaglandin dehydrogenase (15-PGDH) sequence. 5-Hydroxy prostaglandin dehydrogenase blocking peptide can block the formation of protein-antibody complexes during immunohistochemical analysis of 15-PGDH .
    15-Hydroxy prostaglandin dehydrogenase blocking peptide
  • HY-116096
    15-epi-PGE1

    15(R)-Prostaglandin E1; 15-Epiprostaglandin E1

    		 15-PGDH Others
    15-epi-PGE1 (15R-Prostaglandin E1; 15-Epiprostaglandin E1) is a stereoisomer of PGE1 (HY-B0131) but with less biological activity . 15-epi-PGE1 is a non-competitive inhibitor for human placental 15-Hydroxyprostaglandin dehydrogenase (15-PGDH) with an IC50 of 170 μM .
    15-epi-PGE1
  • HY-16968A
    (R)-SW033291

    		15-PGDH Others
    (R)-SW033291 is the R-type enantiomer of SW033291 (HY-16968). (R)-SW033291 is a potent and high-affinity inhibitor of 15-PGDH. (R)-SW033291 increases prostaglandin PGE2 levels in bone marrow and other tissues. (R)-SW033291 also promotes tissue regeneration .
    (R)-SW033291
  • HY-183651
    15-PGDH-IN-5

    		15-PGDH Inflammation/Immunology
    15-PGDH-IN-5 (compound 5) is a sulfoxide-derived 15-PGDH inhibitor. 15-PGDH-IN-5 exhibits higher metabolic stability and superior in vivo exposure compared with the lead compound SW033291 (HY-16968). 15-PGDH-IN-5 inhibits the irreversible oxidative catabolism of PGE2 by 15-PGDH, thereby enhancing the tissue-specific bioavailability of endogenous PGE2. 15-PGDH-IN-5 exerts anti-inflammatory effects and accelerates tissue repair and regeneration, and it is used in studies on tissue injury and fibrosis-related diseases such as inflammatory bowel disease and idiopathic pulmonary fibrosis .
    15-PGDH-IN-5
  • HY-RS06339
    Hpgd Mouse Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    Hpgd Mouse Pre-designed siRNA Set A contains three designed siRNAs for Hpgd gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

    Hpgd Mouse Pre-designed siRNA Set A
    Hpgd Mouse Pre-designed siRNA Set A
  • HY-RS06338
    HPGD Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    HPGD Human Pre-designed siRNA Set A contains three designed siRNAs for HPGD gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    HPGD Human Pre-designed siRNA Set A
    HPGD Human Pre-designed siRNA Set A

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