Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
12 Results for "
3-phosphate dehydrogenase
" in MedChemExpress (MCE) Product Catalog:
Products (12)
12 Results for "3-phosphate dehydrogenase" in MCE Product Catalog:
1
1 Cited Publications
Cat. No.: HY-121970
CAS No.: 27031-00-1
Target:
Phosphoglycerate Dehydrogenase (PHGDH) Reactive Oxygen Species (ROS) HIF/HIF Prolyl-Hydroxylase
Research Areas:
iGP-1 is a cell-permeable, selective mixed inhibitor of mitochondrial sn-glycerol-3-phosphate dehydrogenase (mGPDH), with IC50s of 6.3 μM and 13.6 μM for rat mGPDH activity and H2O2 production, respectively. iGP-1 specifically blocks the mitochondrial component of the glycerophosphate shuttle without affecting cytosolic GPDH. iGP-1 not only inhibits cell proliferation and glutaminolysis, and enhances glycolysis, but also significantly alters key cellular physiological processes such as apoptosis, ROS production, HIF-1α stability and mitochondrial membrane potential. iGP-1 remains active in neutrophil cultures under both normoxic and hypoxic conditions, and serves as an ideal probe for glycerol-3-phosphate metabolic mechanisms. iGP-1 has been applied to studies on prostate cancer and related metabolic pathways .
Cat. No.: HY-113128A
Purity: 99.90%
Target:
Category:
Ketones, Aldehydes, Acids Other Diseases Disease markers Nervous System Disorder Endogenous metabolite Disease Research Fields
Target:
Cat. No.: HY-113128S
Purity: 98.7%
Target:
Research Areas:
Prednisolone hemisuccinate (Prednisolone 21-hemisuccinate) is a prodrug of Prednisolone (HY-17463) and a glucocorticoid. Prednisolone hemisuccinate converts to Prednisolone in vivo. Prednisolone hemisuccinate induces the inactivation of glyceraldehyde-3-phosphate dehydrogenase (GAP-DH) in vitro. Prednisolone hemisuccinate can be used in research related to cataracts .
Cat. No.: HY-E70075
Synonyms: GDH-TIM; GDH-TPI
Target:
Research Areas:
α-Glycerophosphate Dehydrogenase-Triosephosphate (GDH-TIM) is a bifunctional enzyme with activity toward glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. α-Glycerophosphate Dehydrogenase-Triosephosphate catalyzes the conversion of glyceraldehyde 3-phosphate to dihydroxyacetone phosphate. α-Glycerophosphate Dehydrogenase-Triosephosphate can utilize NADH to catalyze the reduction of dihydroxyacetone phosphate to glycerol-1-P .
Cat. No.: HY-113128B
CAS No.: 29849-82-9
Target:
Category:
Target:
Cat. No.: HY-127127A
CAS No.: 104809-38-3
Research Areas:
Deamino-NAD sodium is a structural analog of NAD+ (HY-B0445). Deamino-NAD sodium is involved in glycolysis as a substrate for rabbit muscle glyceraldehyde 3-phosphate dehydrogenase (GPDH), with a Km of 2300 pm, and a Kd of 112 pm .
Cat. No.: HY-P4698
CAS No.: 28130-13-4
Synonyms: NSC 35938
Target:
Research Areas:
Cat. No.: HY-114886
CAS No.: 351978-83-1
Target:
Research Areas:
IGP-5 is a mitochondrial sn-Glycerol 3-phosphate Dehydrogenase (mGPDH) inhibitor with the IC50 of 0.7 μM aganist mGPDH H2O2 production . IGP-5 can be used for study of energy metabolism .
Research Areas:
Prednisolone hemisuccinate (Standard) (Prednisolone 21-hemisuccinate (Standard)) is the analytical standard of Prednisolone hemisuccinate (HY-B1087). This product is intended for research and analytical applications. Prednisolone hemisuccinate (Prednisolone 21-hemisuccinate) is a prodrug of Prednisolone (HY-17463) and a glucocorticoid. Prednisolone hemisuccinate converts to Prednisolone in vivo. Prednisolone hemisuccinate induces the inactivation of glyceraldehyde-3-phosphate dehydrogenase (GAP-DH) in vitro. Prednisolone hemisuccinate can be used in research related to cataracts .
- 1
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
