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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
76 Results for "
5-Fluoro-
" in MedChemExpress (MCE) Product Catalog:
Products (76)
76 Results for "5-Fluoro-" in MCE Product Catalog:
5
5 Cited Publications
Synonyms: 5-Fluoro-2-indolyl deschlorohalopemide
Target:
Research Areas:
Cardiovascular Disease Neurological Disease Inflammation/Immunology Cancer
FIPI is a phospholipase D (PLD) inhibitor with an IC50 for PLD1 and PLD2 of about 25 nM. FIPI regulates cytoskeletal recombination, cell diffusion and chemotaxis. FIPI can be used in cancer research. In addition, FIPI can enhance the secretion and aggregation of platelet dense particles, inhibit thrombosis, reduce ischemic stroke infarct volume and improve nerve function .
3
3 Cited Publications
Synonyms: FdCyd; NSC-48006
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Research Areas:
5-Fluoro-2'-deoxycytidine (FdCyd), a fluoropyrimidine nucleoside analogue, is a DNA methyltransferase (DNMT) inhibitor. 5-Fluoro-2'-deoxycytidine is a tumor-selective proagent of thymidylate synthase inhibitor 5-fluoro-2′-dUMP. 5-Fluoro-2'-deoxycytidine can induce cell cycle arrest in tumor cells through the DNA damage response, and it has anti-tumor activity .
2
2 Cited Publications
Synonyms: Ro 21-9738; 5-Fluoro-5'-deoxyuridine; 5'-DFUR
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Doxifluridine has anticancer activity. Doxifluidine is a 5-FU prodrug. Doxifluridine is a thymidine synthase inhibitor. Doxifluridine can enhance tumor inhibition by synergizing with a variety of drugs .
1
1 Cited Publications
Cat. No.: HY-155878A
CAS No.: 1630828-71-5
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5-Fluoro-2′-deoxy-UTP sodium can be used as a substrate for DNA synthesis .
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Cat. No.: HY-W016819B
CAS No.: 220141-70-8
Synonyms: 5-Fluorouracil-6-carboxylic acid Monohydrate; 5-FOA; 5-Fluoro OA
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5-Fluoroorotic acid monohydrate is the monohydrate salt form of 5-Fluoroorotic acid (HY-W016819).
5-Fluoroorotic acid monohydrate is the inhibitor for thymidylate synthase that acts as a selective agent in yeast molecular genetics. 5-Fluoroorotic acid monohydrate exhibits antimalarial activity .
Cat. No.: HY-W009538
CAS No.: 66335-38-4
Synonyms: 5-Fluoro-5'-deoxycytidine
Research Areas:
5'-Deoxy-5-fluorocytidine (5-Fluoro-5'-deoxycytidine) is a cytidine analog and metabolite of Capecitabine (HY-B0016). 5'-Deoxy-5-fluorocytidine is converted from Capecitabine by carboxylesterase in the liver. 5'-Deoxy-5-fluorocytidine is deaminated by cytidine deaminase to generate 5'-deoxy-5-fluorouridine, which is finally converted into 5-fluorouracil (HY-90006) by thymidine phosphorylase in tumor tissues to exert anti-tumor effects. 5'-Deoxy-5-fluorocytidine is used in the researches for solid tumors such as colorectal cancer, non-small cell lung cancer and breast cancer .
Cat. No.: HY-21045
CAS No.: 16626-02-1
Synonyms: L-5-Fluorotryptophan
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5-Fluoro-L-tryptophan is a competitive vesicular glutamate transporter (VGLUT) inhibitor. 5-Fluoro-L-tryptophan is promising for research of diseases associated with the neurotransmitter systems .
Cat. No.: HY-W616732
CAS No.: 731-98-6
Synonyms: 5'-FDA
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5′-Fluoro-5′-deoxyadenosine is an active compound.
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5-Fluoro-2′-deoxy-UTP can be used as a substrate for DNA synthesis .
Cat. No.: HY-W002914
CAS No.: 56341-41-4
Cat. No.: HY-W007331
CAS No.: 347-54-6
Cat. No.: HY-32748
CAS No.: 41404-58-4
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2-Bromo-5-fluoropyridine acts as a bromofluoropyridine starting material and an azaaryl halide coupling partner. 2-Bromo-5-fluoropyridine participates in an oxygen-promoted, ligand-free Pd (OAc)2-catalyzed Suzuki reaction, reacting with arylboronic acids to produce 5-fluoro-2-aryl-substituted pyridine derivatives. 2-Bromo-5-fluoropyridine can be used to synthesize 5-fluoro-2-(4-(methylsulfonyl) phenyl) pyridine, an intermediate of the GPR119 agonist GSK1292263A .
Cat. No.: HY-32924
CAS No.: 179897-94-0
Cat. No.: HY-W010023
CAS No.: 869557-43-7
Synonyms: 3-Bromo-5-Fluoro-2-pyridinamine
Cat. No.: HY-P5372A
Research Areas:
Cat. No.: HY-44532
CAS No.: 917391-98-1
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5-Fluoro-2-hydroxynicotinaldehyde is a drug intermediate for synthesis of various active compounds.
Cat. No.: HY-23660
CAS No.: 896429-57-5
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5-Fluoro-2-(1H-pyrrol-1-yl)aniline is a drug intermediate for synthesis of various active compounds.
Cat. No.: HY-43489
CAS No.: 2142562-01-2
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5-Fluoro-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl acetate is a drug intermediate for synthesis of various active compounds.
Cat. No.: HY-W009538R
CAS No.: 66335-38-4
Synonyms: 5-Fluoro-5'-deoxycytidine (Standard)
Research Areas:
5'-Deoxy-5-fluorocytidine (Standard) is the analytical standard of 5'-Deoxy-5-fluorocytidine (HY-W009538). This product is intended for research and analytical applications. 5'-Deoxy-5-fluorocytidine (5-Fluoro-5'-deoxycytidine) is a cytidine analog and metabolite of Capecitabine (HY-B0016). 5'-Deoxy-5-fluorocytidine is converted from Capecitabine by carboxylesterase in the liver. 5'-Deoxy-5-fluorocytidine is deaminated by cytidine deaminase to generate 5'-deoxy-5-fluorouridine, which is finally converted into 5-fluorouracil (HY-90006) by thymidine phosphorylase in tumor tissues to exert anti-tumor effects. 5'-Deoxy-5-fluorocytidine is used in the researches for solid tumors such as colorectal cancer, non-small cell lung cancer and breast cancer .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
