Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
21 Results for "
5-HT2 serotonergic receptors
" in MedChemExpress (MCE) Product Catalog:
Products (21)
21 Results for "5-HT2 serotonergic receptors" in MCE Product Catalog:
1
Research Areas:
Mirtazapine (Org3770) is a potent and orally active noradrenergic and specific serotonergic antidepressant (NaSSA) agent. Mirtazapine is also a 5-HT2, 5-HT3, histamine H1 receptor and α2-adrenoceptor antagonist with pKi values of 8.05, 8.1, 9.3 and 6.95, respectively .
Cat. No.: HY-32329
CAS No.: 57262-94-9
Synonyms: Org-8282
Target:
Research Areas:
Setiptiline (Org-8282) is a serotonin receptor antagonist. Setiptiline is a tetracyclic antidepressant (TeCA) which acts as a noradrenergic and specific serotonergic antidepressant (NaSSA). Setiptiline acts as a norepinephrine reuptake inhibitor, α2-adrenergic receptor antagonist, and serotonin receptor antagonist, likely at the 5-HT2A, 5-HT2C, and/or 5-HT3 subtypes, as well as an H1 receptor inverse agonist/antihistamine.
Cat. No.: HY-32329A
CAS No.: 85650-57-3
Synonyms: MO-8282
Target:
Research Areas:
Setiptiline maleate (MO-8282 maleate) is a serotonin receptor antagonist. Setiptiline maleate is a tetracyclic antidepressant (TeCA) which acts as a noradrenergic and specific serotonergic antidepressant (NaSSA). Setiptiline maleate acts as a norepinephrine reuptake inhibitor, α2-adrenergic receptor antagonist, and serotonin receptor antagonist, likely at the 5-HT2A, 5-HT2C, and/or 5-HT3 subtypes, as well as an H1 receptor inverse agonist/antihistamine .
Cat. No.: HY-118796
CAS No.: 77872-41-4
Synonyms: 4-HO-MET; 4-Hydroxy-N-methyl-N-ethyltryptamine
Target:
Research Areas:
4-Hydroxy MET (4-HO-MET; 4-Hydroxy-N-methyl-N-ethyltryptamine) is a synthetic tryptamine psychoactive substance. 4-Hydroxy MET is a partial 5-HT2A receptor agonist, a serotonin transporter inhibitor and weak norepinephrine transporter inhibitor. 4-Hydroxy MET affects emotional, motoric, and cognitive functions via serotonergic hallucinogenic activity .
Cat. No.: HY-W743888
CAS No.: 65527-61-9
Synonyms: 6-Allyl-6-nor-LSD
Target:
Research Areas:
AL-LAD is a 5-HT2A receptor ligand with rat Ki values of 8.1 nM and 3.4 nM. AL-LAD mediates behavioral responses characteristic of serotonergic psychedelics. AL-LAD induces the head-twitch response in male C57BL/6J mice in an inverted-U-shaped dose-dependent manner. AL-LAD exhibits LSD-like behavioral effects in male C57BL/6J mice .
Cat. No.: HY-B0352S
CAS No.: 1216678-68-0
Synonyms: Org3770 d3; 6-Azamianserin d3
Synonyms: D-16949 hydrochloride
Target:
Research Areas:
Anpirtoline (D-16949) hydrochloride is a centrally acting 5-HT1B receptor agonist, with Kis of 28 nM (5-HT1B), 150 nM (5-HT1A) and 1.49 μM (5-HT2). Anpirtoline hydrochloride has serotonergic, antinociceptive, antidepressant-like effects .
Cat. No.: HY-B0352R
CAS No.: 85650-52-8
Synonyms: Org3770 (Standard); 6-Azamianserin (Standard)
Research Areas:
Mirtazapine (Standard) is the analytical standard of Mirtazapine. This product is intended for research and analytical applications. Mirtazapine (Org3770) is a potent and orally active noradrenergic and specific serotonergic antidepressant (NaSSA) agent. Mirtazapine is also a 5-HT2, 5-HT3, histamine H1 receptor and α2-adrenoceptor antagonist with pKi values of 8.05, 8.1, 9.3 and 6.95, respectively .
Cat. No.: HY-B0352S3
CAS No.: 1215587-73-7
Cat. No.: HY-101100A
CAS No.: 98330-05-3
Synonyms: D-16949
Target:
Research Areas:
Anpirtoline (D-16949) is a centrally acting 5-HT1B receptor agonist, with Kis of 28 nM (5-HT1B), 150 nM (5-HT1A) and 1.49 μM (5-HT2). Anpirtoline has serotonergic, antinociceptive, antidepressant-like effects .
Cat. No.: HY-B0352S2
CAS No.: 1215898-55-7
Synonyms: Org3770-d4; 6-Azamianserin-d4
Cat. No.: HY-170053
CAS No.: 763035-03-6
Synonyms: 4-OH-MPT; Meprocin
Target:
Research Areas:
4-Hydroxy MPT (4-OH-MPT), a serotonergic hallucinogen, is a 5-HT2A and 5-HT2B receptors agonist with EC50 values of 3.82 nM and 3.4 nM, respectively .
Target:
Research Areas:
(+)-OSU6162 is an stabilizer on dopaminergic and serotonergic brain signaling. (+)-OSU6162 is a partial agonist of 5-HT2A receptor. (+)-OSU6162 can be used for neurological research .
Cat. No.: HY-106465
CAS No.: 77650-95-4
Research Areas:
Proterguride is a potent dopamine receptor agonist. Proterguride also shows antagonistic properties at the histamine H(1) receptor and alpha(1)-adrenoceptor and partially agonize serotonergic 5-HT2A/B receptor. Proterguride can be used for the research of neurological disease, such as Parkinson's disease .
Cat. No.: HY-32329R
CAS No.: 57262-94-9
Synonyms: Org-8282 (Standard)
Research Areas:
Setiptiline (Standard) is the analytical standard of Setiptiline. This product is intended for research and analytical applications. Setiptiline (Org-8282) is a serotonin receptor antagonist. Setiptiline is a tetracyclic antidepressant (TeCA) which acts as a noradrenergic and specific serotonergic antidepressant (NaSSA). Setiptiline acts as a norepinephrine reuptake inhibitor, α2-adrenergic receptor antagonist, and serotonin receptor antagonist, likely at the 5-HT2A, 5-HT2C, and/or 5-HT3 subtypes, as well as an H1 receptor inverse agonist/antihistamine.
Cat. No.: HY-32329S
CAS No.: 1795024-97-3
Cat. No.: HY-112538
CAS No.: 104113-71-5
Synonyms: 1-NP hydrochloride; 1-NapHThylpiperazine hydrochloride
Target:
Research Areas:
1-1-Naphthylpiperazine hydrochloride (1-NP hydrochloride; 1-Naphthylpiperazine hydrochloride) is a serotonergic derivative of quipazine, which is both an agonist for 5-HT1A receptor and an antagonist for 5-HT2A receptor. 1-1-Naphthylpiperazine hydrochloride induces cell apoptosis. 1-1-Naphthylpiperazine hydrochloride prevents the immunosuppression and photocarcinogenesis .
Cat. No.: HY-32329AR
CAS No.: 85650-57-3
Synonyms: MO-8282 (Standard)
Target:
Research Areas:
Setiptiline (maleate) (Standard) is the analytical standard of Setiptiline (maleate). This product is intended for research and analytical applications. Setiptiline maleate (MO-8282 maleate) is a serotonin receptor antagonist. Setiptiline maleate is a tetracyclic antidepressant (TeCA) which acts as a noradrenergic and specific serotonergic antidepressant (NaSSA). Setiptiline maleate acts as a norepinephrine reuptake inhibitor, α2-adrenergic receptor antagonist, and serotonin receptor antagonist, likely at the 5-HT2A, 5-HT2C, and/or 5-HT3 subtypes, as well as an H1 receptor inverse agonist/antihistamine .
Cat. No.: HY-101745
CAS No.: 91833-49-7
Synonyms: AHR-11325
Target:
Research Areas:
Rocastine (AHR-11325 ) is an orally active H1-histamine receptor inhibitor that selectively binds to and functionally inhibits H1-histamine receptors. Rocastine protects guinea pigs from the lethal effect induced by Histamine (HY-B1204), prevents histamine-induced collapse, and protects guinea pigs from the falling reaction induced by nebulized antigens. Rocastine can be used in the research of allergic diseases .
Cat. No.: HY-W380450A
CAS No.: 52730-46-8
Synonyms: (S)-Viloxazin; (S)-Emovit
Target:
Research Areas:
(S)-Viloxazine ((S)-Viloxazin) is the more pharmacologically active isomer of Viloxazine (HY-W380450). (S)-Viloxazine is an orally active, blood-brain barrier penetrant norepinephrine transporter inhibitor. It also acts as a 5-HT2C receptor agonist and a 5-HT2B receptor inhibitor. (S)-Viloxazine modulates serotonergic and noradrenergic activities, blocks norepinephrine reuptake, and elevates extracellular levels of serotonin, norepinephrine and dopamine in the prefrontal cortex, without inhibiting 5-HT or dopamine uptake into synaptosomes. (S)-Viloxazine can be used in research related to attention deficit hyperactivity disorder and depression .
- 1
- 2
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
