91833-49-7
Chemical Structure
Rocastine
Synonym(s): AHR-11325
- CAS No.: 91833-49-7
- Formula:C13H19N3OS
- Molecular Weight:265.37
IUPAC Name: 2-(2-(dimethylamino)ethyl)-4-methyl-3,4-dihydropyrido[3,2-f][1,4]oxazepine-5(2H)-thione
InChIKey: DPPDPATYPQFYDL-UHFFFAOYSA-N
SMILES: S=C1N(C)CC(CCN(C)C)OC2=NC=CC=C12
Biological Activity: Rocastine (AHR-11325 ) is an orally active H1-histamine receptor inhibitor that selectively binds to and functionally inhibits H1-histamine receptors. Rocastine protects guinea pigs from the lethal effect induced by Histamine (HY-B1204), prevents histamine-induced collapse, and protects guinea pigs from the falling reaction induced by nebulized antigens. Rocastine can be used in the research of allergic diseases[1].
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Rocastine | Rocastine (AHR-11325 ) is an orally active H1-histamine receptor inhibitor that selectively binds to and functionally inhibits H1-histamine receptors. Rocastine protects guinea pigs from the lethal effect induced by Histamine (HY-B1204), prevents histamine-induced collapse, and protects guinea pigs from the falling reaction induced by nebulized antigens. Rocastine can be used in the research of allergic diseases. | |||||||||||||||||||||
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Keywords
