18 Results for "

6-Aminopurine-d1

" in MedChemExpress (MCE) Product Catalog:
Products (18)

18 Results for "6-Aminopurine-d1" in MCE Product Catalog:

4
CCZ01048 TFA
CCZ01048 TFA
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4 Cited Publications
製品番号: HY-P2336A
Target:  

Melanocortin Receptor

研究分野:  

Cancer

CCZ01048 TFA, a α-MSH analogue, exhibits high binding affinity to melanocortin 1 receptor (MC1R) with a Ki of 0.31 nM. CCZ01048 TFA shows rapid internalization into B16F10 melanoma cells and high in vivo stability. CCZ01048 TFA is a promising candidate for PET imaging of malignant melanoma .
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Didemnin B
Didemnin B
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1 Cited Publications
製品番号: HY-105055
CAS 番号: 77327-05-0
純度:  99.95%
Category:  

天然物 Animals Marine natural products Other marine organisms Disease Research Fields Cancer

Target:  

Others

Didemnin B is a depsipeptide extracted from the marine tunicate Trididemnin cyanophorum. Didemnin B can be used for the research of cancer .
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Insulin icodec
Insulin icodec
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製品番号: HY-P4070
CAS 番号: 1188379-43-2
Target:  

Insulin Receptor

研究分野:  

Metabolic Disease

Insulin icodec is an Insulin (HY-P0035) analog that strongly but reversibly binds to albumin. Insulin icodec has long plasma half-life. Insulin icodec modulates insulin receptor activity, controls blood glucose levels, reduces HbA1c levels, and binds reversibly to human serum albumin. Insulin icodec can be used for the research of type 2 diabetes mellitus .
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NODAGA-LM3
NODAGA-LM3
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製品番号: HY-P5362
Target:  

Radionuclide-Drug Conjugates (RDCs) Somatostatin Receptor

研究分野:  

Neurological Disease Cancer

NODAGA-LM3 is a ligand that can cross the blood-brain barrier and targets somatostatin receptor SSTR2 with high affinity (IC50 = 1.3 nM). NODAGA-LM3 does not trigger the internalization of SSTR2 and can inhibit agonist-induced internalization processes. NODAGA-LM3 shows low uptake in normal tissues such as the liver and spleen, but high uptake in the lungs and blood pool. 68Ga-labeled NODAGA-LM3 can serve as a PET imaging agent for well-differentiated neuroendocrine tumors, and is applied in studies related to small cell lung cancer and well-differentiated neuroendocrine tumors .
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ZP3022
ZP3022
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製品番号: HY-P10341
CAS 番号: 1345835-12-2
Target:  

GCGR

研究分野:  

Metabolic Disease

ZP3022 is a dual agonist of glucagon-like peptide-1 (GLP-1) and gastrin that has the ability to sustainably improve glycemic control. Additionally, ZP3022 can effectively increase β-cell mass, promote β-cell proliferation, and enhance the function of pancreatic islets. ZP3022 can be used in anti-diabetic research .
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A3-APO
A3-APO
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製品番号: HY-P11004
Target:  

Bacterial Antibiotic

研究分野:  

Infection

A3-APO is an antimicrobial peptide. A3-APO has a significant antimicrobial activity by a dual mode of action with both membrane disintegration and intracellular target inhibition. A3-APO can deactivate bacterial toxins and increase the expression of anti-inflammatory cytokines (such as IL-4 and IL-10), without antimicrobial resistance. A3-APO accelerates burn wounds healing in mice infection model of Acinetobacter baumannii and Staphylococcus aureus .
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Azaline B
Azaline B
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製品番号: HY-P10472
CAS 番号: 134457-28-6
Target:  

GnRH Receptor

研究分野:  

Endocrinology

Azaline B is an antagonist for gonadotropin-releasing hormone (GnRH) with IC50 of 1.37 nM, Azaline B can be used in research of sex hormone-related pathological states, ovulation induction and male contraception .
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N1-Glutathionyl-spermidine disulfide
N1-Glutathionyl-spermidine disulfide
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製品番号: HY-P4757
CAS 番号: 108081-77-2
Target:  

Parasite

研究分野:  

Others

N1-Glutathionyl-spermidine disulfide is a substrate of trypanothione reductase .
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EphA4 agonist compound 23
EphA4 agonist compound 23
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製品番号: HY-P11243
Target:  

Ephrin Receptor

研究分野:  

Neurological Disease

EphA4 agonist compound 23 is a novel EphA4 agonist peptide mimic. EphA4 agonist compound 23 exhibits high affinity, high selectivity, and significant receptor activation ability. EphA4 agonist compound 23 is commonly used in the study of neurodegenerative diseases .
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AP102
AP102
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製品番号: HY-P2434
CAS 番号: 846569-60-6
Target:  

Somatostatin Receptor

研究分野:  

Neurological Disease Metabolic Disease Cancer

AP102 is a dual SSTR2/SSTR5-specific somatostatin analog (SSA). AP102 is a disulfide-bridged octapeptide SSA containing synthetic iodinated amino acids. AP102 binds with subnanomolar affinity to SSTR2 and SSTR5 (IC50: 0.63 and 0.65 nM, respectively). AP102 does not bind to SSTR1 or SSTR3. AP102 can be used for acromegaly and neuroendocrine tumors research .
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NODAGA-LM3 TFA
NODAGA-LM3 TFA
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製品番号: HY-P5362A
Target:  

Radionuclide-Drug Conjugates (RDCs) Somatostatin Receptor

研究分野:  

Cancer

NODAGA-LM3 TFA is a ligand that can cross the blood-brain barrier and targets somatostatin receptor SSTR2 with high affinity (IC50 = 1.3 nM). NODAGA-LM3 TFA does not trigger the internalization of SSTR2 and can inhibit agonist-induced internalization processes. NODAGA-LM3 TFA shows low uptake in normal tissues such as the liver and spleen, but high uptake in the lungs and blood pool. 68Ga-labeled NODAGA-LM3 TFA can serve as a PET imaging agent for well-differentiated neuroendocrine tumors, and is applied in studies related to small cell lung cancer and well-differentiated neuroendocrine tumors .
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TAK 044
TAK 044
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製品番号: HY-105168
CAS 番号: 157380-72-8
Target:  

Endothelin Receptor

研究分野:  

Cardiovascular Disease

TAK 044 is an antagonist of Endothelin Receptor. TAK 044 strongly inhibits ET-induced deterioration in various animal models. TAK 044 can be used in study ET-related diseases such as acute myocardial infarction,acute renal failure, acute hepatic malfunction, and subarachnoid hemorrhage .
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EMD 55068
EMD 55068
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製品番号: HY-P2075
CAS 番号: 126784-34-7
Target:  

Renin

研究分野:  

Endocrinology

EMD 55068 is a renin antagonist. EMD 55068 inhibits the uptake of taurocholate .
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mcK6A1
mcK6A1
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製品番号: HY-P10876
Target:  

Amyloid-β

研究分野:  

Neurological Disease

mcK6A1 is an inhibitor for the aggregation of amyloid-β (Aβ), that selectively binds to the 16KLVFFA21 segment of Aβ42, forms an extended β-folded structure, and inhibits the formation of Aβ42 oligomers. mcK6A1 can be used in research of Alzheimer's disease and other amyloid-related diseases .
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KH-1
KH-1
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製品番号: HY-P11901
Target:  

Ras HDAC Apoptosis

研究分野:  

Cancer

KH-1 is a KRAS G12D/HDAC2 dual-target inhibitor with Kd values of 11.63 nM and 20.17 nM, respectively. KH-1 induces pancreatic cell apoptosis, cell cycle arrest, and inhibits cell proliferation, invasion and migration, as well as suppresses tumor growth in pancreatic cancer xenograft models. KH-1 can be used for the research of pancreatic cancer .
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FAPα/DPP4 flurogenic substrate-1
FAPα/DPP4 flurogenic substrate-1
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製品番号: HY-P11823
Target:  

Fluorescent Dye

研究分野:  

Inflammation/Immunology Cancer

FAPα/DPP4 fluorogenic substrate-1 is a fluorogenic macrocyclic peptide substrate that can be cleaved by FAPα and DPP4. FAPα/DPP4 fluorogenic substrate-1 can be used in the research of cancer and type 2 diabetes .
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JR11-PEG3-DOTA-PSMA-03
JR11-PEG3-DOTA-PSMA-03
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製品番号: HY-P11488
Target:  

Radionuclide-Drug Conjugates (RDCs) Somatostatin Receptor PSMA

研究分野:  

Cancer

JR11-PEG3-DOTA-PSMA-03 (Compound 2) is an RDC-related compound containing the chelating agent DOTA (HY-W053583), the JR11 peptide (SSTR2 antagonist), and the PSMA ligand. JR11-PEG3-DOTA-PSMA-03 shows SSTR2-binding affinities and PSMA-binding affinities, with IC50 s of 94.0 nM, 81.8 nM, respectively. JR11-PEG3-DOTA-PSMA-03 can be radiolabeled with [ 68Ga]. [ 68Ga] radiolabeled JR11-PEG3-DOTA-PSMA-03 can be used in diagnostic studies of neuroendocrine differentiated prostate cancer .
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JR11-PEG3-HBED-CC-PSMA-03
JR11-PEG3-HBED-CC-PSMA-03
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製品番号: HY-P11485
Target:  

Radionuclide-Drug Conjugates (RDCs) Somatostatin Receptor PSMA

研究分野:  

Cancer

JR11-PEG3-HBED-CC-PSMA-03 (Compound 1) is an RDC-related compound containing the chelating agent HBED-CC, the JR11 peptide (SSTR2 antagonist), and the PSMA ligand. JR11-PEG3-HBED-CC-PSMA-03 shows SSTR2-binding affinities and PSMA-binding affinities, with IC50 s of 59.2 nM, 57.0 nM, respectively. JR11-PEG3-HBED-CC-PSMA-03 can be radiolabeled with [ 68Ga]. [ 68Ga] radiolabeled JR11-PEG3-HBED-CC-PSMA-03 can be used in diagnostic studies of neuroendocrine differentiated prostate cancer .
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Assay Types