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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
32 Results for "
7α-hydroxylase
" in MedChemExpress (MCE) Product Catalog:
Products (32)
32 Results for "7α-hydroxylase" in MCE Product Catalog:
17
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Cardiovascular Disease Inflammation/Immunology Endocrinology Cancer
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9 Cited Publications
Cat. No.: HY-104081
CAS No.: 11041-12-6
Synonyms: Cholestyramine resin; Colestyramine
Research Areas:
Cholestyramine (Cholestyramine resin) is an orally active bile acid sequestrant. Cholestyramine upregulates the expression of intestinal Apical sodium-dependent bile acid transporter and hepatic Cholesterol 7α-hydroxylase. Cholestyramine induces the expression of intestinal and hepatic cholesterol synthesis genes as well as hepatic lipogenesis genes, and promotes bile acid- and neutral sterol-mediated reverse cholesterol transport. Cholestyramine reduces intestinal cholesterol absorption and induces cholesterol efflux. Cholestyramine is applicable to research related to coronary artery disease, atherosclerotic cardiovascular disease and atherosclerosis .
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1
1 Cited Publications
Category:
Natural Products Animals Marine natural products Other marine organisms Disease Research Fields Cancer
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1
1 Cited Publications
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GSK2945 hydrochloride is a class of tertiary amine, and is a highly specific Rev-erbα/REV-ERBα (mouse/human reverse erythroblastosis virus α) antagonist with EC50s of 21.5 μM and 20.8 μM, respectively. GSK2945 hydrochloride enhances cholesterol 7α-hydroxylase (CYP7A1) level and cholesterol metabolism .
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Cat. No.: HY-W008226
CAS No.: 480-66-0
Synonyms: 2,4,6-trihydroxyacetophenone; 1-(2,4,6-Trihydroxyphenyl)ethanone
Category:
Metabolic Disease Plants Curcuma comosa Roxb. Infection other families Ketones, Aldehydes, Acids Phenols Polyphenols Disease Research Fields Zingiberaceae
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Cat. No.: HY-B2012
CAS No.: 85509-19-9
Synonyms: DPX-H6573
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Flusilazole (DPX-H6573) is a broad-spectrum fungicide and cytochrome P-450 inhibitor that can be used in studies related to fungal infections .
Cat. No.: HY-P10447
CAS No.: 103651-09-8
Synonyms: Fengycin IX; SNA-60-367-3
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Synonyms: Cholesterol 5β,6β-epoxide; 5β,6β-Epoxycholesterol
Cat. No.: HY-P4755
CAS No.: 282726-24-3
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Cat. No.: HY-E71455
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24-Hydroxycholesterol 7α-hydroxylase (EC 1.14.14.26): a P450 heme-thiolate protein that is found in liver microsomes and in ciliary non-pigmented epithelium.
Cat. No.: HY-E71458
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Research Areas:
25/26-Hydroxycholesterol 7α-hydroxylase (EC 1.14.14.29): a P-450 (heme-thiolate) protein.
Cat. No.: HY-P3100
CAS No.: 939960-34-6
Cat. No.: HY-125357
CAS No.: 148619-41-4
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Cat. No.: HY-117147
CAS No.: 1438071-12-5
Target:
Research Areas:
GSK2945 is a class of tertiary amine, and is a highly specific Rev-erbα/REV-ERBα (mouse/human reverse erythroblastosis virus α) antagonist with EC50s of 21.5 μM and 20.8 μM, respectively. GSK2945 enhances cholesterol 7α-hydroxylase (CYP7A1) level and cholesterol metabolism .
Synonyms: 7α-Hydroxydehydroepiandrosterone; 3β,7α-Dihydroxy-Δ5-androsten-17-one
Category:
Cat. No.: HY-158104
Cat. No.: HY-105191
CAS No.: 143393-27-5
Synonyms: RS-21607
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Azalanstat (RS-21607) is an orally active lanosterol 14α-demethylase inhibitor. Azalanstat exerts a cholesterol-lowering effect by inhibiting cholesterol synthesis and regulating HMG-CoA Reductase (HMGCR), and shows an additive effect when used in combination with Cholestyramine (HY-104081). Azalanstat is used in the study of hypercholesterolemia .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
