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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
12 Results for "
ALT (Alanine Aminotransferase)
" in MedChemExpress (MCE) Product Catalog:
Products (12)
12 Results for "ALT (Alanine Aminotransferase)" in MCE Product Catalog:
2
2 Cited Publications
Cat. No.: HY-W013755
CAS No.: 117-84-0
Synonyms: DNOP; Di-n-octyl phthalate; Phthalic acid dioctyl ester
Research Areas:
Dioctyl phthalate (DNOP) is a plasticizer. Dioctyl phthalate increases the activities of alanine aminotransferase (ALT) and alkaline phosphatase (ALP) in the liver, as well as the levels of creatinine and urea in the kidney. Exposure to Dioctyl phthalate disrupts the homeostasis of the intestinal microbial community, increases the abundance of pathogenic bacteria, and reduces the abundance of beneficial bacteria such as Lactobacillus. Dioctyl phthalate induces significant and dose-dependent inflammatory responses in the liver, spleen and kidney of mice .
Cat. No.: HY-113820
CAS No.: 549494-39-5
Target:
Research Areas:
AZD4619 is an orally active, selective peroxisome proliferator-activated receptor α (PPARα) agonist. AZD4619 increases alanine aminotransferase 1 (ALT1) protein expression in a dose-dependent manner in human, but not in rat primary hepatocytes. AZD4619 is a lipid-lowering drug .
Cat. No.: HY-176192
Research Areas:
SMU-14a is a selective Toll-like receptor 3 (TLR3) inhibitor wirh an IC50 of 0.18 μM. SMU-14a reduces phosphorylation of p65, ERK, and TBK1 via NF-κB, MAPK, and IRF3 signaling pathways. SMU-14a inhibits IL-6 secretion in mouse peritoneal macrophages, downregulates TNF-α in human peripheral blood monocytes and decreases serum alanine aminotransferase (ALT) and aspartate aminotransferase (AST) levels. SMU-14a can be used for the research of acute hepatitis .
Cat. No.: HY-W013755S
CAS No.: 93952-13-7
Synonyms: DNOP-d4; Di-n-octyl phthalate-d4; Phthalic acid dioctyl ester-d4
Cat. No.: HY-175676
Target:
Research Areas:
THR-β agonist 10 is an orally active and selective THR-β agonist, with an EC50 of 11 nM. THR-β agonist 10 significantly reduces ALT (Alanine Aminotransferase), TC (Total Cholesterol), and LDL-C (Low-Density Lipoprotein Cholesterol) levels, and improves steatosis, ballooning, inflammation and fibrosis in the metabolic dysfunction-associated steatohepatitis (MASH) mouse model. THR-β agonist 10 can be used for the study of MASH .
Cat. No.: HY-W101609
CAS No.: 140-26-1
Target:
Category:
Cat. No.: HY-P702494
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: GPT; Glutamate Pyruvate Transaminase 1; Glutamic--Pyruvic Transaminase; Glutamic--Pyruvic Transaminase 1; ALT1; Alanine Aminotransferase 1; GPT1; Alanine Aminotransferase; SGPT; Alanine Transaminase; ALT; AAT1; Glutamic-Pyruvate Transaminase (Alanine Amin
Species:
Human
Source:
E. coli
Cat. No.: HY-P75158
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: GPT; Glutamate Pyruvate Transaminase 1; Glutamic--Pyruvic Transaminase; Glutamic--Pyruvic Transaminase 1; ALT1; Alanine Aminotransferase 1; GPT1; Alanine Aminotransferase; SGPT; Alanine Transaminase; ALT; AAT1; Glutamic-Pyruvate Transaminase (Alanine Amin
Species:
Rat
Source:
Sf9 insect cells
Cat. No.: HY-P75797
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: GPT2; Glutamic Pyruvate Transaminase (Alanine Aminotransferase) 2; Glutamic--Pyruvic Transaminase 2; Glutamate Pyruvate Transaminase 1; ALT2; Glutamic--Pyruvic Transaminase 1; Alanine Aminotransferase 2; Glutamic--Alanine Transaminase 1; Glutamate Pyruvat
Species:
Rat
Source:
Sf9 insect cells
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
