1 Result for "

AMPAR modulator 12

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "AMPAR modulator 12" in MCE Product Catalog:

Cat. No.: HY-183101
CAS No.: 2163787-60-6
Target:  

iGluR NADPH Oxidase

Research Areas:  

Neurological Disease

AMPAR modulator-12 is a blood-brain barrier-permeable AMPAR positive allosteric modulator. AMPAR modulator-12 reduces NOX-1 expression, enhances AMPAR-mediated currents, promotes excitatory postsynaptic transmission and restores AMPAR function. AMPAR modulator-12 enhances excitatory and inhibitory synaptic transmission, reduces burst firing in the lateral habenula after withdrawal, and produces rapid and sustained antidepressant-like effects. AMPAR modulator-12 is applicable for the research of depression .
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