1 Result for "

ANI-7

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "ANI-7" in MCE Product Catalog:

Cat. No.: HY-117102
CAS No.: 931417-26-4
Purity:  98.13%
Research Areas:  

Cancer

ANI-7 is an activator of aryl hydrocarbon receptor (AhR) pathway. ANI-7 inhibits the growth of multiple cancer cells, and potently and selectively inhibits the growth of MCF-7 breast cancer cells with a GI50 of 0.56 μM. ANI-7 induces CYP1-metabolizing mono-oxygenases by activating AhR pathway, and also induces DNA damage, checkpoint Kinase 2 (Chk2) activation, S-phase cell cycle arrest, and cell death in sensitive breast cancer cell lines .
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