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Antibacterial activity

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2237

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54

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1

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841

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1

GMP Molecules

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-N0565
    Doxycycline
    170+ Cited Publications

    		 MMP Bacterial Antibiotic Parasite Infection Neurological Disease Inflammation/Immunology Cancer
    Doxycycline, an antibiotic, is an orally active and broad-spectrum metalloproteinase (MMP) inhibitor . Doxycycline shows antibacterial activity and anti-cancer cell proliferation activity .
    Doxycycline
  • HY-N0565B
    Doxycycline hyclate
    170+ Cited Publications

    Doxycycline hydrochloride hemiethanolate hemihydrate; WC2031

    		 Antibiotic MMP Bacterial Parasite Infection Neurological Disease Inflammation/Immunology Cancer
    Doxycycline hyclate, an antibiotic, is an orally active and broad-spectrum metalloproteinase (MMP) inhibitor. Doxycycline hyclate shows antibacterial activity and anti-cancer cell proliferation activity. Doxycycline hyclate can be used to construct gene expression regulation models .
    Doxycycline hyclate
  • HY-N0565A
    Doxycycline hydrochloride
    170+ Cited Publications

    		 MMP Bacterial Antibiotic Parasite Infection Neurological Disease Inflammation/Immunology Cancer
    Doxycycline hydrochloride, an antibiotic, is an orally active and broad-spectrum metalloproteinase (MMP) inhibitor . Doxycycline hydrochloride shows antibacterial activity and anti-cancer cell proliferation activity. Doxycycline hydrochloride can be used to construct gene expression regulation models .
    Doxycycline hydrochloride
  • HY-N0055
    Chlorogenic acid
    25+ Cited Publications

    3-O-Caffeoylquinic acid; Heriguard; NSC-407296

    		 HIF/HIF Prolyl-Hydroxylase Reactive Oxygen Species (ROS) Bacterial Influenza Virus Endogenous Metabolite Infection Cardiovascular Disease Inflammation/Immunology Cancer
    Chlorogenic acid is a major phenolic compound in Lonicera japonica Thunb. It is an orally active antioxidant activity, antibacterial, hepatoprotective, cardioprotective, anti-inflammatory, antipyretic, neuroprotective, anti-obesity, antiviral, anti-microbial, anti-hypertension compound .
    Chlorogenic acid
  • HY-N7057
    Nonanoic acid
    1 Publications Verification

    Pelargonic acid

    		 Environmental Pollutants Endogenous Metabolite Bacterial Infection
    Nonanoic acid (Pelargonic acid) is a naturally-occurring saturated fatty acid with nine carbon atoms. Nonanoic acid significantly reduces bacterial translocation, enhances antibacterial activity, and remarkably increases the secretion of porcine β-defensins 1 (pBD-1) and pBD-2 .
    Nonanoic acid
  • HY-B0991
    Amoxapine
    4 Publications Verification

    CL-67772

    		 Bacterial Autophagy Infection Cardiovascular Disease Neurological Disease Inflammation/Immunology
    Amoxapine (CL-67772) is a norepinephrine reuptake blocker and a 5-HT2/5-HT3 antagonist. Amoxapine can be used for the research of depression. Amoxapine has antibacterial activity. Amoxapine can enhance the killing effect of macrophages on mycobacterium by inducing autophagy, while protecting the cells from death .
    Amoxapine
  • HY-P4648
    H-Trp-Trp-Trp-OH

    Trp-Trp-Trp

    		 Bacterial Infection
    H-Trp-Trp-Trp-OH (Trp-Trp-Trp) is a tripeptide consisting of tryptophan. H-Trp-Trp-Trp-OH has antibacterial activity. H-Trp-Trp-Trp-OH is a human bitter taste receptor hTAS2R14 agonist .
    H-Trp-Trp-Trp-OH
  • HY-N3488
    Isodiospyrin

    		Topoisomerase Bacterial Fungal Infection Cancer
    Isodiospyrin, a natural dimeric naphthoquinone, is a human DNA topoisomerase I (Topoisomerase) inhibitor. Isodiospyrin can prevent both DNA relaxation and kinase activities of human topoisomerase I. Isodiospyrin shows anticancer, antibacterial and antifungal activities .
    Isodiospyrin
  • HY-P1926
    A-54556A

    		Antibiotic Bacterial Infection
    A-54556A (ADEP 1) is an acyldepsipeptide (ADEP) antibiotic. A-54556A shows antibacterial activity against a broad range of Gram-positive bacteria .
    A-54556A
  • HY-N2612
    O-Methyldauricine
    1 Publications Verification

    Daurisoline-d4; Dau-d4; (-)-O-Methyldauricine

    		 Fungal Bacterial Infection Neurological Disease
    O-Methyldauricine ((-)-O-Methyldauricine) is an alkaloid with benzylisoquinoline group, which can be separated from P. ophthalmicus. O-Methyldauricine has antibacterial activity .
    O-Methyldauricine
  • HY-122356A
    Ambazone

    		Bacterial Cancer
    Ambazone is an orally active membrane active antitumor agent. Ambazone also shows antibacterial and weak antiviral activities .
    Ambazone
  • HY-W037825
    Pterin

    		Bacterial Infection Cancer
    Pterin is a Pteridine with antibacterial activity, which is found in C. croceus. Pterin reduces the proliferation and biofilm production in E. coli, P. aeruginosa, and S. mutans. Pterin is promising for research of cancers and infections .
    Pterin
  • HY-158761
    Polyaminopropyl biguanide

    PAPB

    		 Bacterial Infection
    Polyaminopropyl biguanide (PAPB), a propyl analogue of polyhexamethylene biguanide, is a broad spectrum, fast acting bactericide with antibacterial activity. Polyaminopropyl biguanide can be used as a preservative in cosmetic products .
    Polyaminopropyl biguanide
  • HY-N3353
    Luteone

    		Bacterial Fungal Infection
    Luteone is a natural isoflavone, with antioxidant, antibacterial and antifung activities .
    Luteone
  • HY-N7252
    Daphnin

    		Bacterial Infection
    Daphnin is one of the major coumarin bioactive components with antibacterial activity. Daphnin is isolated from the whole herb of Daphne odora (Thunb.), which is a folk medicine in China for the relief of fever .
    Daphnin
  • HY-W110662
    Transtorine

    		Bacterial Infection
    Transtorine is a quinoline alkaloid, found from Ephedra transitoria, with antibacterial activity .
    Transtorine
  • HY-N9488
    Girinimbine

    Girinimbin

    		 Apoptosis Bacterial Parasite Infection Inflammation/Immunology Cancer
    Girinimbine (Girinimbin) is a carbazole alkaloid with a variety of biological effects. Girinimbine can induce apoptosis, and has antitrypanosomal, antiplatelet activity, antibacterial activity, anti-inflammatory, antioxidant and antitumor activities .
    Girinimbine
  • HY-W013158
    Trimethyloctadecylammonium bromide

    		Dynamin Infection
    Trimethyloctadecylammonium bromide is an inhibitor of dynamin, with an IC50 value of 1.9 μM for dynamin I. Trimethyloctadecylammonium bromide exhibits antibacterial activity against Staphylococcus aureus .
    Trimethyloctadecylammonium bromide
  • HY-103658
    Myramistin

    Miramistin

    		 Bacterial Infection
    Myramistin (Miramistin) is an antibacterial agent targeting bacterial cell membrane. Myramistin can bind to the negatively charged surface of bacteria through its cationic properties, disrupt the integrity of the bacterial cell membrane, inhibit bacterial metabolism and growth, and induce cell death, thus exerting antibacterial activity .
    Myramistin
  • HY-B1852
    Sulfometuron-methyl

    		Bacterial Fungal Infection
    Sulfometuron-methyl is a herbicide and also a powerful inhibitor of the enzyme acetolactate synthase (ALS). It exhibits antibacterial and antifungal activities, capable of inhibiting the activity of Salmonella. typhimurium ALS II and Escherichia. coli ALS III .
    Sulfometuron-methyl
  • HY-14762
    Besifloxacin

    		Antibiotic Bacterial Infection
    Besifloxacin is a fluoroquinolone antimicrobial agent. Besifloxacin can inhibit cytokine production by monocytes. Besifloxacin has broad-spectrum antibacterial activity .
    Besifloxacin
  • HY-113806
    (±)-Trolline

    (±)-Oleracein E

    		 Bacterial Influenza Virus Apoptosis Infection Inflammation/Immunology
    (±)-Trolline ((±)-Oleracein E), an isoquinoline alkaloid, exhibits antibacterial activity against respiratory bacteria and antiviral activity against influenza virus A and B. (±)-Trolline significantly induces HSC apoptosis. (±)-Trolline can be used for the research of liver fibrosis .
    (±)-Trolline
  • HY-N16590
    Diphylloside A

    		Bacterial Infection
    Diphylloside A is a flavonoid compound with antioxidant activity. Diphylloside A exhibits significant antibacterial activity against Pseudomonas aeruginosa .
    Diphylloside A
  • HY-D0200
    Adipic acid dihydrazide

    Adipodihydrazide

    		 Bacterial Drug Intermediate Biochemical Assay Reagents Infection
    Adipic acid dihydrazide (Adipodihydrazide) is an antibacterial agent and crosslinking agent. Adipic acid dihydrazide can be used for the preparation of hydrogels. Adipic acid dihydrazide exhibits antibacterial activity against both Gram-positive and Gram-negative bacteria, such as Enterobacter aerogenes (MIC: 0.081 mg/mL) and Salmonella enterica (MIC: 0.99 mg/mL). Adipic acid dihydrazide is also an important intermediate that can be utilized in the synthesis of other active compounds .
    Adipic acid dihydrazide
  • HY-N10227
    Geodin

    		PAI-1 Antibiotic Infection Inflammation/Immunology
    Geodin, a fungal metabolite, shows antibacterial activity. Geodin also is an inhibitor of plasminogen activator inhibitor- 1 (PAI-1) .
    Geodin
  • HY-12480
    Lanopepden

    GSK 1322322

    		 Bacterial Infection
    Lanopepden (GSK 1322322) is a peptidyl peptidase (PDF) inhibitor. Lanopepden inhibits PDF activity, preventing bacterial protein synthesis, thereby exerting antibacterial activity. Lanopepden is primarily effective against Gram-positive bacteria. Lanopepden is used in the study of acute bacterial skin and skin structure infections .
    Lanopepden
  • HY-122918
    Moracin T

    		Bacterial Infection
    Moracin T can be isolated from the bark of mulberry trees and has antibacterial activity.
    Moracin T
  • HY-153696
    MRL-436

    		DNA/RNA Synthesis Bacterial Infection
    MRL-436 is a RNA polymerase inhibitor with antibacterial activity. MRL-436 exerts its antibacterial activity dependent on residue 622 of the RNA polymerase β' subunit and the RNAP ω subunit. MRL-436 inhibits Rifampicin (HY-B0272)-resistant RNA polymerase derivatives and exhibits antibacterial activity against Rifampicin-resistant strains .
    MRL-436
  • HY-131554
    Tibezonium iodide

    		Bacterial Antibiotic Infection
    Tibezonium iodide, an oropharyngeal disinfectant, has antibacterial activity for the prevention of mouth infections .
    Tibezonium iodide
  • HY-105373
    PNU 101850

    		Drug Intermediate Infection
    PNU 101850 is an Eperezolid (HY-10393) ester prodrug. PNU 101850 acquires antibacterial activity after conversion to the parent drug Eperezolid .
    PNU 101850
  • HY-122356
    Ambazone monohydrate

    		Bacterial Cancer
    Ambazone monohydrate is an orally active membrane active antitumor agent. Ambazone monohydrate also shows antibacterial and weak antiviral activities .
    Ambazone monohydrate
  • HY-N16397
    Anhydrofulvic acid

    		Bacterial Infection
    Anhydrofulvic acid is a polyketide with antibacterial activity (notably against MRSA, MIC=8 mg/mL). Anhydrofulvic acid is promising for research of Gram-positive infections (e.g., skin, bloodstream) .
    Anhydrofulvic acid
  • HY-W127616A
    β-Sitosterol acetate, 95%

    Sitosteryl acetate, 95%

    		 Bacterial Infection
    β-Sitosterol acetate, 95% (Sitosteryl acetate, 95%) is a sterol that can be isolated from Hechtia glomerata Zucc., which has antibacterial activity and has a MIC value of 100µg/mL against carbapenem-resistant Acinetobacter baumannii .
    β-Sitosterol acetate, 95%
  • HY-P2569
    Malformin A1

    		Apoptosis Cancer
    Malformin A1, a cyclic pentapeptide isolated from Aspergillus niger, possess a range of bioactive properties including antibacterial activity. Malformin A1 shows potent cytotoxic activities on human colorectal cancer cells. Malformin A1 induces apoptosis by activating PARP, caspase 3, -7, and -9 .
    Malformin A1
  • HY-131907
    LpxC-IN-5

    		Bacterial Infection
    LpxC-IN-5 is a potent non-hydroxamate LpxC (UDP-3-O-acyl-N-acetylglucosamine deacetylase) inhibitor with an IC50 of 20 nM. LpxC-IN-5 shows antibacterial activity against E. coli ATCC25922, P. aeruginosa ATCC27853, K. pneumoniae ATCC13883 and P. aeruginosa 5567 with MIC of 16, 4, 64, and 4 μg/mL, respectively .
    LpxC-IN-5
  • HY-N12743
    Farobin A

    		Bacterial Infection Inflammation/Immunology
    Farobin A is a natural compound with antibacterial, antioxidant and anti-inflammatory activities. Farobin A against Streptococcus mutans ATCC 25175 and Streptococcus sobrinus ATCC 33478. Farobin A shows anti-inflammatory activity on cytokine IL-6 and TNF-α .
    Farobin A
  • HY-163463
    PTP1B-IN-25

    		Phosphatase Fungal HIV Bacterial Infection Metabolic Disease
    PTP1B-IN-25 (Compound 19) is a PTP1B inhibitor with remarkable antiviral, antibacterial, and antidiabetic activities. PTP1B-IN-25 has IC50 values of 0.37 μM, 8.6 μM, 3.7 μM, and 29 μM against PTP1B, HIV, α-Glucosidase, and methicillin-resistant Staphylococcus aureus (MRSA) respectively .
    PTP1B-IN-25
  • HY-N14164
    Echinoserine

    		Bacterial Infection
    Echinoserine is an analog of Echinomycin (HY-106101) with antibacterial activity .
    Echinoserine
  • HY-176144
    Antibacterial agent 278

    		Bacterial Infection
    Antibacterial agent 278 (compound B1) is an antibacterial agent. Antibacterial agent 278 exhibites potent activity against Gram-positive bacteria .
    Antibacterial agent 278
  • HY-21745
    MurA-IN-4

    		Bacterial Infection
    MurA-IN-4 has antibacterial activity and is a MurA inhibitor that inhibits bacterial cell wall synthesis .
    MurA-IN-4
  • HY-173080
    Antibacterial agent 267

    		Bacterial Infection
    Antibacterial agent 267 (Compound h19) is a pleuromutilin derivative with a potent antibacterial activity on Gram-positive bacteria. Antibacterial agent 267 shows an antibacterial activity in methicillin-resistant Staphylococcus aureus (MRSA)-infected mouse models .
    Antibacterial agent 267
  • HY-N10050
    Coreoside B

    14-Hydroxycoreoside A

    		 Bacterial Infection
    Coreoside B (14-Hydroxycoreoside A) can be isolated from Coreopsis tinctoria Nutt. and has weak antibacterial activity .
    Coreoside B
  • HY-162527
    Antibacterial agent 216

    		Bacterial Infection
    Antibacterial agent 216 (Compound 2a) is an antibacterial agent that exhibits significant bactericidal effects when combined with INH and RIF. Antibacterial agent 216 has demonstrated remarkable in vitro anti-tuberculosis activity against Mtb H37Rv and MDR clinical isolates and can be used for tuberculosis research .
    Antibacterial agent 216
  • HY-163197
    JSF-2827

    		Bacterial Infection
    JSF-2827 is a benzothiophene with antibacterial activity against Enterococcus faecium .
    JSF-2827
  • HY-161172
    Antibacterial agent 178

    		Bacterial Infection
    Antibacterial agent 178 (compound A10) is a potent antibacterial agent. Antibacterial agent 178 shows antibacterial activities for Xanthomonas oryzae pv. oryzae and Xanthomonas oryzae pv. oryzicola with EC50s of 5.32 mg/L and 7.58 mg/L, respectively. Antibacterial agent 178 targets the translational regulator (CsrA) and the virulence regulator (Xoc3530) .
    Antibacterial agent 178
  • HY-N3789
    Dunnianol

    		Bacterial Infection
    Dunnianol is a natural sesqui-neoligan with moderate antibacterial activity. Dunnianol inhibits Staphylococcus aureus and methicillin-resistant Staphylococcus aureus (MRSA).
    Dunnianol
  • HY-N10281
    Asperglaucin B

    		Bacterial Infection
    Asperglaucin B is an alkylated salicylaldehyde derivative from the fungus Aspergillus chevalieri SQ-8, with antibacterial activities. Asperglaucin B displays potent antibacterial activities against two plant pathogens Pseudomonas syringae pv actinidae (Psa) and Bacillus cereus, with an MIC value of 6.25 μM .
    Asperglaucin B
  • HY-N14699
    Diphenicillin

    Ancillin free acid; 2-Biphenylyl penicillin free acid; SKF-12141 free acid

    		 Penicillin-binding protein (PBP) Bacterial Infection
    Diphenicillin (Ancillin (free acid); 2-Biphenylyl penicillin (free acid); SKF-12141 (free acid)) is a Penicillinase (HY-E70012)- resistant penicillin with antibacterial activity. Diphenicillin shows good antibacterial effects against Gram-positive cocci. Diphenicillin is promising for research of infectious diseases caused by Gram-positive cocci such as staphylococci, pneumococci, and group A streptococci .
    Diphenicillin
  • HY-B1852R
    Sulfometuron-methyl (Standard)

    		Bacterial Reference Standards Fungal Infection
    Sulfometuron-methyl (Standard) is the analytical standard of Sulfometuron-methyl. This product is intended for research and analytical applications. Sulfometuron-methyl is a herbicide and also a powerful inhibitor of the enzyme acetolactate synthase (ALS). It exhibits antibacterial and antifungal activities, capable of inhibiting the activity of Salmonella. typhimurium ALS II and Escherichia. coli ALS III .
    Sulfometuron-methyl (Standard)
  • HY-173254
    MurA-IN-6

    		Bacterial Infection
    MurA-IN-6 (Compound L16) is a selective MurA inhibitor with an IC50 value of 26.63 μM. MurA-IN-6 exerts antibacterial activity by blocking the activity of MurA, which is crucial in bacterial cell wall synthesis .
    MurA-IN-6

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