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Results for "

Antiprotozoal

" in MedChemExpress (MCE) Product Catalog:

By Targets:	5-HT Receptor (2) Antibiotic (26) Apoptosis (6) Bacterial (34) c-Myc (1) Caspase (1) Drug Metabolite (2) Endogenous Metabolite (4) Fungal (10) HDAC (1) IFNAR (1) Influenza Virus (1) Interleukin Related (1) Isotope-Labeled Compounds (9) Lactate Dehydrogenase (3) Mitochondrial Metabolism (1) NF-κB (1) NO Synthase (1) Parasite (79) Phosphatase (1) Reactive Oxygen Species (ROS) (5) Reference Standards (17) STAT (1) TNF Receptor (1) Wnt (2)
By Research Areas:	Cancer (18) Cardiovascular Disease (1) Infection (86) Inflammation/Immunology (13) Metabolic Disease (3) Neurological Disease (3)

By Targets:

5-HT Receptor (2)

Antibiotic (26)

Apoptosis (6)

Bacterial (34)

c-Myc (1)

Caspase (1)

Drug Metabolite (2)

Endogenous Metabolite (4)

Fungal (10)

HDAC (1)

IFNAR (1)

Influenza Virus (1)

Interleukin Related (1)

Isotope-Labeled Compounds (9)

Lactate Dehydrogenase (3)

Mitochondrial Metabolism (1)

NF-κB (1)

NO Synthase (1)

Parasite (79)

Phosphatase (1)

Reactive Oxygen Species (ROS) (5)

Reference Standards (17)

STAT (1)

TNF Receptor (1)

Wnt (2)

By Research Areas:

Cancer (18)

Cardiovascular Disease (1)

Infection (86)

Inflammation/Immunology (13)

Metabolic Disease (3)

Neurological Disease (3)

Inhibitors & Agonists

Peptides

Natural
Products

Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-101848

Latrunculin B Maximum Cited Publications 6 Publications Verification	Fungal	Infection
Latrunculin B, an antimicrobial marine alkaloid, is an actin polymerization inhibitor. Latrunculin B regulates pulmonary vein electrophysiological characteristics and attenuates stretch-induced arrhythmogenesis. Antifungal and antiprotozoal activity .

HY-B0565

Ronidazole 2 Publications Verification	Parasite Bacterial	Infection
Ronidazole is a potent and orally active *antiprotozoal* and anti-microbial agent. Ronidazole acts as a veterinary agent against Tritrichomonas foetus in cats models. Ronidazole can be used the research of forhistomoniasis and swine dysentery .

HY-B0295

Chloroxine 2 Publications Verification	Bacterial Antibiotic Parasite	Infection
Chloroxine is one of the important 8-hydroxyquinoline derivative. Chloroxine has effective antibacterial, antifungal, antiprotozoal and antiamoebic activities, especially used in treating the intestinal amebiasis. Chloroxine is also used in the treatment of dandruff and seborrheic dermatitis of the scalp .

HY-100711

Prodigiosin 3 Publications Verification Prodigiosine; NSC47147	Bacterial Apoptosis Wnt Fungal Parasite	Infection Inflammation/Immunology Cancer
Prodigiosin (Prodigiosine) is a red pigment produced by bacteria as a bioactive secondary metabolite. Prodigiosin is a potent inhibitor of the Wnt/β-catenin pathway. Prodigiosin has antibacterial, antifungal, antiprotozoal, antimalarial, immunosuppressive, and anticancer properties .

HY-W040073

Nifurtimox 1 Publications Verification	Parasite Lactate Dehydrogenase	Infection Cancer
Nifurtimox, an antiprotozoal agent, which is generally used for the treatment of infections with Trypanosoma cruzi, has been used in the therapy of neuroblastoma. Nifurtimox affects enzyme activity of lactate dehydrogenase (LDH).

HY-B0688

Dapsone 4 Publications Verification 4,4′-Diaminodiphenyl sulfone; DDS	Antibiotic Parasite Bacterial Reactive Oxygen Species (ROS)	Infection Inflammation/Immunology
Dapsone (4,4′-Diaminodiphenyl sulfone) is an orally active and blood-brain penetrant sulfonamide antibiotic with bacteriostatic, antimycobacterial and antiprotozoal activities . Dapsone?exerts effective antileprosy activity?and inhibits folate synthesis in cell extracts of?M. leprae. Dapsone is used for dermatologic disorder research, including leprosy, dermatitis herpetiformis, acne vulgaris et al .

HY-A0059

Nifuratel 3 Publications Verification NF 113; SAP 113; Methylmercadone	Bacterial Parasite Antibiotic Fungal Apoptosis STAT Interleukin Related TNF Receptor	Infection Inflammation/Immunology Cancer
Nifuratel (NF 113) is an orally active broad-spectrum antibiotic with antiprotozoal, antibacterial, anticancer and anti-inflammatory activities, and has good inhibitory effects on Candida and Trichomonas. Nifuratel is also a STAT3 inhibitor, which significantly inhibits the growth and proliferation of human gastric cancer cells and induces apoptosis. In addition, Nifuratel also inhibits mast cell-mediated antigen hypersensitivity reactions and can be used in the study of IgE-mediated allergic diseases .

HY-N1363

Royal Jelly acid Maximum Cited Publications 6 Publications Verification (E)-Queen Bee Acid; (E)-10-Hydroxy-2-decenoic acid	Endogenous Metabolite NO Synthase NF-κB Parasite IFNAR	Infection Neurological Disease Inflammation/Immunology Cancer
Royal Jelly Acid ((E)-Queen Bee Acid) is a major fatty acid found in royal jelly with oral bioavailability, exhibiting anti-inflammatory, anticancer, antimalarial, antiprotozoal, and neuroregulatory activities. Royal Jelly Acid can be used for research in various fields, including cancer, infections, immune inflammation, and neurological diseases .

HY-N0840

Bruceantin 2 Publications Verification (-)-Bruceantin; NCI165563; NSC165563	c-Myc Caspase Mitochondrial Metabolism Apoptosis Parasite	Infection Cancer
Bruceantin ((-)-Bruceantin) is a quassinoid found in B. javanica. Bruceantin activates caspase signaling pathway, causes the mitochondrial dysfunction, inhibits cell proliferation, induces cell differentiation and apoptosis. Bruceantin exhibits anti-leukemia and antiprotozoal activities .

HY-17581

Buparvaquone 5 Publications Verification	Parasite Antibiotic	Infection
Buparvaquone is a hydroxynaphthoquinone antiprotozoal agent related to parvaquone and atovaquone.

HY-B0175

Toltrazuril 3 Publications Verification BAY-i 9142	Parasite Antibiotic	Infection
Toltrazuril (BAY-i 9142) is an antiprotozoal agent that acts upon Coccidia parasites.

HY-17008

Toltrazuril sulfone 1 Publications Verification Ponazuril	Parasite	Infection
Toltrazuril sulfone (Ponazuril) is a metabolite of Toltrazuril (HY-B0175), with antiprotozoal activity. Toltrazuril sulfone is a triazine anticoccidial that is developed to prevent coccidiosis in poultry .

HY-114275

Justicidin B	Fungal Parasite Apoptosis	Infection Cardiovascular Disease Cancer
Justicidin B is a potent anticancer lignan and proapoptotic agent. Justicidin B is also a bone resorption inhibitor, and has strong antiviral, fungicidal, antiprotozoal effects. Justicidin B significantly inhibits platelet aggregation .

HY-107496

Imidocarb dipropionate 1 Publications Verification	Parasite Antibiotic	Infection
Imidocarb dipropionate is a potent *antiprotozoal* agent. Imidocarb dipropionate is active against the parasite B. bovis with an IC₅₀ of 87 μg/mL .

HY-B1143

Broxaldine Brobenzoxaldine	Parasite Fungal Bacterial	Infection
Broxaldine (Brobenzoxaldine) is an antiprotozoal agent. Broxaldine inhibits *Clostridium difficile* with a MIC value of 4 µM, and has antifungal effects .

HY-19910

Acoziborole 3 Publications Verification SCYX-7158; AN5568	Parasite	Infection
Acoziborole (SCYX-7158) is an effective, safe and orally active antiprotozoal agent for the research of human african trypanosomiasis (HAT). In the *T. b. brucei* S427 strain, the MIC value for SCYX-7158 is 0.6 μg/mL .

HY-N11173

cis-Melilotoside	Others	Metabolic Disease
cis-Melilotoside, an o-Coumaric acid derivative, shows potent antioxidant activity. cis-Melilotoside has antiprotozoal activity moderately against T. cruzi with an IC₅₀ of 78.2 ug/mL .

HY-B1147

Diloxanide furoate 1 Publications Verification	Parasite	Infection
Diloxanide furoate is the proagent of Diloxanide. Diloxanide furoate is a potent and orally active anti-protozoal agent and can be used for the research of amebiasis, mild intestinal amebiasis or asymptomatic cyst carriers .

HY-16349

Nimorazole 1 Publications Verification K-1900	Parasite Antibiotic	Infection Cancer
Nimorazole (K-1900), a 2-nitroimidazole, is a hypoxic cell-radiation sensitizer. Nimorazole has anti-infective and anti-protozoal against trichomoniasis. Nimorazole has the potential for head and neck cancer .

HY-15537

Tilbroquinol 1 Publications Verification	Parasite Bacterial	Infection
Tilbroquinol is an orally active halogenated hydroxyquinoline antiprotozoal agent, mainly used for anti-amoebic infections . Tilbroquinol targets intestinal protozoa and Entamoeba histolytica to eliminate parasites in the intestinal lumen. Tilbroquinol can be used in research related to intestinal infections, intestinal amoebiasis and hepatic amoebiasis .

HY-136436

Ternidazole hydrochloride	Drug Metabolite Antibiotic Bacterial Fungal	Infection Inflammation/Immunology
Ternidazole hydrochloride is a nitroimidazole Antibiotic with anti-pathogenic microbial activity. Ternidazole hydrochloride kills and inhibits the visible growth of Clostridium perfringens type A in vitro. Ternidazole hydrochloride helps improve the therapeutic efficacy against bacterial vaginosis, candidal vaginitis and mixed vaginitis. Ternidazole hydrochloride effectively alleviates chronic alcoholism. Ternidazole hydrochloride can be used in research related to vaginitis, pathogenic microbial infections and chronic alcoholism .

HY-135611

Imidocarb 1 Publications Verification	Parasite Antibiotic	Infection
Imidocarb is a potent antiprotozoal agent. Imidocarb is active against the parasite B. bovis with an IC₅₀ of 87 μg/mL .

HY-119972

Diloxanide	Parasite	Infection
Diloxanide is an anti-protozoal agent and can be used for the research of asymptomatic-intestinal amebiasis caused by Entamoeba histolytica or some other protozoal infections. Diloxanide is an active luminal amebicide and hydrolyzed in the gastrointestinal tract from its proagent Diloxanide furoate (HY-B1147) .

HY-N7516

4'-Hydroxy-2,4-dimethoxychalcone	Parasite Bacterial Fungal	Infection
4'-Hydroxy-2,4-dimethoxychalcone is a natural chalcone derivatives in the red herbal resin of Dracaena cochinchinensis. 4'-Hydroxy-2,4-dimethoxychalcone displays a wide range of biological activities including antimalarial, antiprotozoal, antibacterial, antifungal activity .

HY-B0565R

Ronidazole (Standard)	Reference Standards Parasite Bacterial	Infection
Ronidazole (Standard) is the analytical standard of Ronidazole. This product is intended for research and analytical applications. Ronidazole is a potent and orally active antiprotozoal and anti-microbial agent. Ronidazole acts as a veterinary agent against Tritrichomonas foetus?in cats models. Ronidazole can be used the research of forhistomoniasis?and?swine?dysentery .

HY-137990

Questin	Bacterial Parasite Phosphatase	Infection Cancer
Questin is an anthraquinone compound and antibacterial agent. Questin can be isolated from marine-derived fungi and plants. Questin inhibits Cdc25B phosphatase. Questin exhibits antibacterial activity against V. harveyi, V. anguillarum, V. cholerae, and V. parahemolyticus with MIC values of 31.25 µg/mL, 62.5 µg/mL, 62.5 µg/mL, and 125 µg/mL. Questin displays *antiprotozoal* activity against the animal protozoan pathogen Tritrichomonas foetus, with a MIC of 12.5 µg/mL. Questin has anticancer activity against lung and colon cancer .

HY-B0217S

Nitazoxanide-d4 NTZ-d₄; NSC-697855-d₄	Influenza Virus	Others
Nitazoxanide-d₄ is the deuterium labeled Nitazoxanide, which is an antiprotozoal agent.

HY-B0688S2

Dapsone-13C12 4,4′-Diaminodiphenyl sulfone-¹³C₁₂; DDS-¹³C₁₂	Isotope-Labeled Compounds Antibiotic Parasite Bacterial Reactive Oxygen Species (ROS)	Infection Inflammation/Immunology
Dapsone- ¹³C₁₂ is the ¹³C₁₂ labeled Dapsone (HY-B0688). Dapsone (4,4′-Diaminodiphenyl sulfone) is an orally active and blood-brain penetrant sulfonamide antibiotic with bacteriostatic, antimycobacterial and antiprotozoal activities. Dapsone exerts effective antileprosy activity and inhibits folate synthesis in cell extracts of M. leprae. Dapsone is used for dermatologic disorder research, including leprosy, dermatitis herpetiformis, acne vulgaris et al .

HY-119900

Carnidazole	Parasite Antibiotic	Infection
Carnidazole is an *antiprotozoal* agent of the nitroimidazole class. Carnidazole is used for the research of Trichomonas infection .

HY-100711A

Prodigiosin hydrochloride 3 Publications Verification Prodigiosine hydrochloride	Bacterial Apoptosis Fungal Wnt Parasite	Infection Inflammation/Immunology Cancer
Prodigiosin (Prodigiosine) hydrochloride is a red pigment produced by bacteria as a bioactive secondary metabolite. Prodigiosin hydrochloride is a potent proapoptotic agent, and inhibits Wnt/β-catenin pathway. Prodigiosin hydrochloride has antibacterial, antifungal, antiprotozoal, antimalarial, immunosuppressive, and anticancer properties .

HY-101660

Nifursemizone Etafurazone; NF161	Parasite	Infection
Nifursemizone is an antiprotozoal agent.

HY-N6587

Betulinic acid methyl ester Methyl betulinate	Parasite	Others
Betulinic acid methyl ester, a betulinic acid derivative, possesses antiprotozoal activity .

HY-N11100

Geranin A	Parasite	Infection
Geranin A is an A-type proanthocyanidin. Geranin A can be isolated from the antiprotozoal extract of Geranium niveum .

HY-G0016

N-Acetyl dapsone MADDS; Monoacetyldapsone	Drug Metabolite	Others
N-Acetyl dapsone (MADDS) is the major metabolite of Dapsone (HY-B0688). Dapsone is an orally active and blood-brain penetrant sulfonamide antibiotic with bacteriostatic, antimycobacterial and antiprotozoal activities .

HY-N7632

5-Desmethylsinensetin	Bacterial	Infection Inflammation/Immunology
5-desmethylsinensetin, isolated from Artemisia princeps , possesses antiprotozoal activity. 5-desmethylsinensetin shows IC₅₀ values of 0.4 μg/mL on T. cruzi epimastigotes and 75.1 μg/mL on trypomastigotes, respectively .

HY-136440

Hydroxymetronidazole Metronidazole-OH	Bacterial Parasite	Infection
Hydroxymetronidazole (Metronidazole-OH) is a metabolite of Metronidazole belonging to the class of nitroimidazoles. Hydroxymetronidazole can be used for the research of certain bacterial and *protozoal* diseases in poultry, swine dysentery and genital trichomoniasis in cattle .

HY-136440R

Hydroxymetronidazole (Standard) Metronidazole-OH (Standard)	Reference Standards Bacterial Parasite	Infection
Hydroxymetronidazole (Standard) is the analytical standard of Hydroxymetronidazole. This product is intended for research and analytical applications. Hydroxymetronidazole (Metronidazole-OH) is a metabolite of Metronidazole belonging to the class of nitroimidazoles. Hydroxymetronidazole can be used for the research of certain bacterial and protozoal diseases in poultry, swine dysentery and genital trichomoniasis in cattle .

HY-P3451

Lefleuganan	Parasite	Infection
Lefleuganan is a potent *antiprotozoal* agent .

HY-118996B

Isometamidium chloride hydrochloride	Parasite	Infection
Isometamidium chloride hydrochloride is an antiprotozoal agent, that exhibits activity against trypanosome. Isometamidium chloride hydrochloride can be used in research of african sleeping sickness .

HY-19594

Teclozan WIN 13146	Parasite	Infection
Teclozan (WIN 13146) is an antiprotozoal agent, class in benzylamine derivatives. Teclozan intervenes in the phospholipid metabolism preventes the formation of arachidonic acid. Teclozan acts in the intestinal lumen being effective in Anti-G. intestinalis. Teclozan can be used for the research of protozoan infections .

HY-B0226A

(E)-Nitrofurazone (E)-Nitrofural	Bacterial Parasite	Infection
(E)-Nitrofurazone ((E)-Nitrofural) is a topical broad-spectrum antibacterial agent effective against both Gram-negative and Gram-positive bacteria. (E)-Nitrofurazone also possesses antiprotozoal and antiparasitic activities. (E)-Nitrofurazone is commonly used in the research of superficial wounds, burns, skin infections, pyoderma, infectious skin diseases, trypanosomiasis, and acute bacillary dysentery .

HY-118996A

Isometamidium chloride	Parasite	Infection
Isometamidium chloride is an antiprotozoal agent, that exhibits activity against trypanosome. Isometamidium chloride can be used in research of african sleeping sickness .

HY-B0175R

Toltrazuril (Standard) BAY-i 9142 (Standard)	Reference Standards Parasite Antibiotic	Infection
Toltrazuril (Standard) is the analytical standard of Toltrazuril. This product is intended for research and analytical applications. Toltrazuril (BAY-i 9142) is an antiprotozoal agent that acts upon Coccidia parasites.

HY-105061

Misonidazole Ro 7-0582; SR 1354	Bacterial Parasite	Infection Cancer
Misonidazole (Ro 7-0582; SR 1354) is a hypoxic tumor cell radiosensitizer . Misonidazole also has antimicrobial effects .

HY-107496R

Imidocarb dipropionate (Standard)	Reference Standards Parasite Antibiotic	Infection
Imidocarb (dipropionate) (Standard) is the analytical standard of Imidocarb (dipropionate). This product is intended for research and analytical applications. Imidocarb dipropionate is a potent antiprotozoal agent. Imidocarb dipropionate is active against the parasite B. bovis with an IC50 of 87 μg/mL .

HY-W040073R

Nifurtimox (Standard)	Reference Standards Parasite Lactate Dehydrogenase	Infection Cancer
Nifurtimox (Standard) is the analytical standard of Nifurtimox. This product is intended for research and analytical applications. Nifurtimox, an antiprotozoal agent, which is generally used for the treatment of infections with Trypanosoma cruzi, has been used in the therapy of neuroblastoma. Nifurtimox affects enzyme activity of lactate dehydrogenase (LDH).

HY-B1147R

Diloxanide furoate (Standard)	Reference Standards Parasite	Infection
Diloxanide furoate (Standard) is the analytical standard of Diloxanide furoate. This product is intended for research and analytical applications. Diloxanide furoate is the proagent of Diloxanide. Diloxanide furoate is a potent and orally active anti-protozoal agent and can be used for the research of amebiasis, mild intestinal amebiasis or asymptomatic cyst carriers .

HY-P2450

Leucinostatin A Antibiotic P168	Fungal Antibiotic	Infection Cancer
Leucinostatin A (Antibiotic P168) is a nonapeptide exerting a remarkable activity especially against Candida albicans and Cryptococcus neoformans. Leucinostatin A is a hydrophobic nonapeptide antibiotic. Leucinostatin A inhibits prostate cancer growth through reduction of insulin-like growth factor-I expression in prostate stromal cells. Antiprotozoal activies .

HY-P1954

Epinecidin-1 Piscidin-1 (22-42)	Bacterial	Infection Cancer
Epinecidin-1 (Piscidin-1 (22-42)) is a highly potent, multi-functional Antimicrobial Peptide (AMP) produced by Orange-spotted grouper (Epinephelus coioides). Epinecidin-1 has many functional usages including antibacterial, antifungal, antiviral, antiprotozoal, anticancer, immunomodulatory, and wound healing properties .

HY-B0688S1

Dapsone-d4 4,4′-Diaminodiphenyl sulfone-d₄; DDS-d₄	Isotope-Labeled Compounds Antibiotic Parasite Bacterial Reactive Oxygen Species (ROS)	Infection Inflammation/Immunology
Dapsone-d₄ is the deuterium labeled Dapsone. Dapsone (4,4′-Diaminodiphenyl sulfone) is an orally active and blood-brain penetrant sulfonamide antibiotic with bacteriostatic, antimycobacterial and antiprotozoal activities . Dapsone?exerts effective antileprosy activity?and inhibits folate synthesis in cell extracts of?M. leprae. Dapsone is used for dermatologic disorder research, including leprosy, dermatitis herpetiformis, acne vulgaris et al .

Cat. No.	Product Name	Target	Research Area

HY-P3451

Lefleuganan	Parasite	Infection
Lefleuganan is a potent *antiprotozoal* agent .

HY-P1954

Epinecidin-1 Piscidin-1 (22-42)	Bacterial	Infection Cancer
Epinecidin-1 (Piscidin-1 (22-42)) is a highly potent, multi-functional Antimicrobial Peptide (AMP) produced by Orange-spotted grouper (Epinephelus coioides). Epinecidin-1 has many functional usages including antibacterial, antifungal, antiviral, antiprotozoal, anticancer, immunomodulatory, and wound healing properties .

HY-P5696

Xenopsin precursor fragment	Bacterial Parasite Fungal	Infection
Xenopsin precursor fragment is an antimicrobial peptide, and has antibacterial/antifungal (10-500 μg/mL) and anti-protozoal (MIC: 2-20 μg/mL) activity .

HY-P1954A

Epinecidin-1 TFA Piscidin-1 (22-42) TFA	Bacterial	Infection Cancer
Epinecidin-1 (Piscidin-1 (22-42)) TFA is a highly potent, multi-functional Antimicrobial Peptide (AMP) produced by Orange-spotted grouper (Epinephelus coioides). Epinecidin-1 TFA has many functional usages including antibacterial, antifungal, antiviral, antiprotozoal, anticancer, immunomodulatory, and wound healing properties .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-101848

Latrunculin B Maximum Cited Publications 6 Publications Verification	Infection Animals Classification of Application Fields Marine natural products Sponge Disease Research Fields	Fungal
Latrunculin B, an antimicrobial marine alkaloid, is an actin polymerization inhibitor. Latrunculin B regulates pulmonary vein electrophysiological characteristics and attenuates stretch-induced arrhythmogenesis. Antifungal and antiprotozoal activity .

HY-100711

Prodigiosin 3 Publications Verification Prodigiosine; NSC47147	Anti-inflammation/Immunoregulatory Antifungal Classification of Application Fields Antibacterial Disease Research Other Antibiotics Food Research Infection Microorganisms Antibiotics Pigments Anticancer Inflammation/Immunology Disease Research Fields Source Classification	Bacterial Apoptosis Wnt Fungal Parasite
Prodigiosin (Prodigiosine) is a red pigment produced by bacteria as a bioactive secondary metabolite. Prodigiosin is a potent inhibitor of the Wnt/β-catenin pathway. Prodigiosin has antibacterial, antifungal, antiprotozoal, antimalarial, immunosuppressive, and anticancer properties .

HY-N1363

Royal Jelly acid Maximum Cited Publications 6 Publications Verification (E)-Queen Bee Acid; (E)-10-Hydroxy-2-decenoic acid	Animals Ketones, Aldehydes, Acids Endogenous metabolite Source Classification	Endogenous Metabolite NO Synthase NF-κB Parasite IFNAR
Royal Jelly Acid ((E)-Queen Bee Acid) is a major fatty acid found in royal jelly with oral bioavailability, exhibiting anti-inflammatory, anticancer, antimalarial, antiprotozoal, and neuroregulatory activities. Royal Jelly Acid can be used for research in various fields, including cancer, infections, immune inflammation, and neurological diseases .

HY-N0840

Bruceantin 2 Publications Verification (-)-Bruceantin; NCI165563; NSC165563	Simaroubaceae Classification of Application Fields Brucea antidysenterica J.F.Mill. Terpenoids Diterpenoids Plants Disease Research Fields Brucea javanica (L.) Merr. Source Classification Cancer	c-Myc Caspase Mitochondrial Metabolism Apoptosis Parasite
Bruceantin ((-)-Bruceantin) is a quassinoid found in B. javanica. Bruceantin activates caspase signaling pathway, causes the mitochondrial dysfunction, inhibits cell proliferation, induces cell differentiation and apoptosis. Bruceantin exhibits anti-leukemia and antiprotozoal activities .

HY-114275

Justicidin B	Acanthaceae Lignans Phenylpropanoids Plants Duhaldea wissmanniana (Hand.-Mazz.) Anderb. Source Classification	Fungal Parasite Apoptosis
Justicidin B is a potent anticancer lignan and proapoptotic agent. Justicidin B is also a bone resorption inhibitor, and has strong antiviral, fungicidal, antiprotozoal effects. Justicidin B significantly inhibits platelet aggregation .

HY-N11173

cis-Melilotoside	Simple Phenylpropanols Orchidaceae Phenylpropanoids Plants Dendrobium chryseum Z. H. Tsi et S. C. Chen Source Classification	Others
cis-Melilotoside, an o-Coumaric acid derivative, shows potent antioxidant activity. cis-Melilotoside has antiprotozoal activity moderately against T. cruzi with an IC₅₀ of 78.2 ug/mL .

HY-136436

Ternidazole hydrochloride	Structural Classification Natural Products Classification of Application Fields Other Diseases Endogenous metabolite Disease Research Fields Source Classification	Drug Metabolite Antibiotic Bacterial Fungal
Ternidazole hydrochloride is a nitroimidazole Antibiotic with anti-pathogenic microbial activity. Ternidazole hydrochloride kills and inhibits the visible growth of Clostridium perfringens type A in vitro. Ternidazole hydrochloride helps improve the therapeutic efficacy against bacterial vaginosis, candidal vaginitis and mixed vaginitis. Ternidazole hydrochloride effectively alleviates chronic alcoholism. Ternidazole hydrochloride can be used in research related to vaginitis, pathogenic microbial infections and chronic alcoholism .

HY-N7516

4'-Hydroxy-2,4-dimethoxychalcone	Infection Chalcones Monophenols Flavonoids Classification of Application Fields Phenols Umbelliferae Plants Disease Research Fields Carphephorus corymbosus (Nutt.) Torr. & A.Gray Source Classification	Parasite Bacterial Fungal
4'-Hydroxy-2,4-dimethoxychalcone is a natural chalcone derivatives in the red herbal resin of Dracaena cochinchinensis. 4'-Hydroxy-2,4-dimethoxychalcone displays a wide range of biological activities including antimalarial, antiprotozoal, antibacterial, antifungal activity .

HY-137990

Questin	Classification of Application Fields Marine natural products Endogenous metabolite Infection Quinones Human Gut Microbiota Metabolites Microorganisms Anthraquinones Phenols Polyphenols Marine microorganism Disease Research Fields Source Classification	Bacterial Parasite Phosphatase
Questin is an anthraquinone compound and antibacterial agent. Questin can be isolated from marine-derived fungi and plants. Questin inhibits Cdc25B phosphatase. Questin exhibits antibacterial activity against V. harveyi, V. anguillarum, V. cholerae, and V. parahemolyticus with MIC values of 31.25 µg/mL, 62.5 µg/mL, 62.5 µg/mL, and 125 µg/mL. Questin displays *antiprotozoal* activity against the animal protozoan pathogen Tritrichomonas foetus, with a MIC of 12.5 µg/mL. Questin has anticancer activity against lung and colon cancer .

HY-100711A

Prodigiosin hydrochloride 3 Publications Verification Prodigiosine hydrochloride	Infection Alkaloids Microorganisms Pyrrole Alkaloids Classification of Application Fields Pigments Inflammation/Immunology Disease Research Fields Source Classification Food Research	Bacterial Apoptosis Fungal Wnt Parasite
Prodigiosin (Prodigiosine) hydrochloride is a red pigment produced by bacteria as a bioactive secondary metabolite. Prodigiosin hydrochloride is a potent proapoptotic agent, and inhibits Wnt/β-catenin pathway. Prodigiosin hydrochloride has antibacterial, antifungal, antiprotozoal, antimalarial, immunosuppressive, and anticancer properties .

HY-N6587

Betulinic acid methyl ester Methyl betulinate	Triterpenes other families Classification of Application Fields Terpenoids Other Diseases Plants Disease Research Fields Source Classification	Parasite
Betulinic acid methyl ester, a betulinic acid derivative, possesses antiprotozoal activity .

HY-N11100

Geranin A	Phenols Polyphenols Plants Geranium niveum S.Watson Geraniaceae Source Classification	Parasite
Geranin A is an A-type proanthocyanidin. Geranin A can be isolated from the antiprotozoal extract of Geranium niveum .

HY-N7632

5-Desmethylsinensetin	Classification of Application Fields Flavones Plants Compositae Infection Monophenols Flavonoids other families Erythrina eriotriocha Phenols Inflammation/Immunology Disease Research Fields Source Classification	Bacterial
5-desmethylsinensetin, isolated from Artemisia princeps , possesses antiprotozoal activity. 5-desmethylsinensetin shows IC₅₀ values of 0.4 μg/mL on T. cruzi epimastigotes and 75.1 μg/mL on trypomastigotes, respectively .

HY-P2450

Leucinostatin A Antibiotic P168	Infection Natural Products Microorganisms Classification of Application Fields Disease Research Fields Source Classification	Fungal Antibiotic
Leucinostatin A (Antibiotic P168) is a nonapeptide exerting a remarkable activity especially against Candida albicans and Cryptococcus neoformans. Leucinostatin A is a hydrophobic nonapeptide antibiotic. Leucinostatin A inhibits prostate cancer growth through reduction of insulin-like growth factor-I expression in prostate stromal cells. Antiprotozoal activies .

HY-120154

Palitantin (±)-Palitantin	Infection Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Disease Research Fields Source Classification	Parasite Endogenous Metabolite
Palitantin ((±)-Palitantin), a metabolite of Penicillium frequentans on Leishmania brasiliensis, has antiprotozoal effect against Leishmania brasiliensis .

HY-N14364

Flavipucine Flavipucin	Natural Products Microorganisms Source Classification	Antibiotic Bacterial Parasite
Flavipucine (Flavipucin), a glutarimide antibiotic, is found in the strain of Aspergillus flavipes F-2090/7. Flavipucine has antibacterial activity against B. subtilis. Flavipucine has antiprotozoal activity. Flavipucine has cytotoxic activity against several cancer cells .

HY-N10255

Trypacidin	Infection Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Disease Research Fields Source Classification	Parasite
Trypacidin is the conidia-bound metabolite with antiprotozoal activity. Trypacidin has a protective function against phagocytes both in the environment and during the infection process .

HY-N9179

3′,4′,5′,5,6,7-Hexamethoxyflavone	Infection Flavonoids Classification of Application Fields Flavones Lupinus perennis L. Plants Compositae Disease Research Fields Source Classification	Parasite
3′,4′,5′,5,6,7-Hexamethoxyflavone is a flavonoid with antiprotozoal activity. 3′,4′,5′,5,6,7-Hexamethoxyflavone inhibits trypanosoma bruceirhodesiense with IC₅₀ of 21.3 μM (8.58 g/mL) .

HY-136438

Toltrazuril sulfoxide 1 Publications Verification	Natural Products Classification of Application Fields Metabolic Disease Endogenous metabolite Inflammation/Immunology Disease Research Fields Source Classification	Endogenous Metabolite Parasite
Toltrazuril sulfoxide is a short-lived intermediary metabolite of Toltrazuril (HY-B0175), and then can be metabolized to the reactive toltrazuril sulfone (TZR-SO2) in vivo. Toltrazuril is an antiprotozoal agent that acts upon Coccidia parasites .

HY-119604

Cafamycin	Microorganisms Antibiotics Other Antibiotics Source Classification	Antibiotic Bacterial
Cafamycin is a polyether antibiotic active against gram-positive bacteria, including Staphylococcus aureus. Cafamycin also demonstrates insecticidal and antiprotozoal activities. Cafamycin is isolated from the culture fluid of Streptomyces sp., an organism producing the anthracycline antibiotic galtamycin .

HY-136438R

Toltrazuril sulfoxide (Standard)	Natural Products Endogenous metabolite Source Classification	Reference Standards Endogenous Metabolite Parasite
Toltrazuril sulfoxide (Standard) is the analytical standard of Toltrazuril sulfoxide. This product is intended for research and analytical applications. Toltrazuril sulfoxide is a short-lived intermediary metabolite of Toltrazuril (HY-B0175), and then can be metabolized to the reactive toltrazuril sulfone (TZR-SO2) in vivo. Toltrazuril is an antiprotozoal agent that acts upon Coccidia parasites .

HY-N15655

Ravenelin	Structural Classification Microorganisms Xanthones Phenols Source Classification	Bacterial
Ravenelin is a xanthone that can be isolated from the endophytic fungus Exserohilum rostratum. Ravenelin exhibits antiprotozoal and antibacterial activity. Ravenelin is active against gram-positive bacterial strains. Ravenelin can be studied for hit-to-lead development, especially for Chagas Disease .

HY-N10547

6-O-Methylcatalpol	Scrophularia ningpoensis Hemsl. Polymer products Scrophulariaceae Plants Saccharides Monosaccharides	Parasite
6-O-Methylcatalpol can be isolated from the roots of Scrophularia ningpoensis. 6-O-Methylcatalpol has anti-protozoal activity against Trypanosoma b. rhodesiense and Leishmania donovani (IC₅₀: 32.5 and 8.3 μg/mL) .

Cat. No.	Product Name	Chemical Structure

HY-B0217S

Nitazoxanide-d4
Nitazoxanide-d₄ is the deuterium labeled Nitazoxanide, which is an antiprotozoal agent.

HY-B0688S2

Dapsone-13C12

Dapsone- ¹³C₁₂ is the ¹³C₁₂ labeled Dapsone (HY-B0688). Dapsone (4,4′-Diaminodiphenyl sulfone) is an orally active and blood-brain penetrant sulfonamide antibiotic with bacteriostatic, antimycobacterial and antiprotozoal activities. Dapsone exerts effective antileprosy activity and inhibits folate synthesis in cell extracts of M. leprae. Dapsone is used for dermatologic disorder research, including leprosy, dermatitis herpetiformis, acne vulgaris et al .

HY-B0688S1

Dapsone-d4

Dapsone-d₄ is the deuterium labeled Dapsone. Dapsone (4,4′-Diaminodiphenyl sulfone) is an orally active and blood-brain penetrant sulfonamide antibiotic with bacteriostatic, antimycobacterial and antiprotozoal activities . Dapsone?exerts effective antileprosy activity?and inhibits folate synthesis in cell extracts of?M. leprae. Dapsone is used for dermatologic disorder research, including leprosy, dermatitis herpetiformis, acne vulgaris et al .

HY-B0175S

Toltrazuril-d3
Toltrazuril-d₃ is deuterated labeled Toltrazuril. Toltrazuril (BAY-i 9142) is an antiprotozoal agent that acts upon Coccidia parasites.

HY-119900S

Carnidazole-d3
Carnidazole-d3 is deuterium labeled Carnidazole (HY-119900). Carnidazole exhibits antiprotozoal efficacy against Trichomonas gallinae .

HY-W040073S

Nifurtimox-d4
Nifurtimox-d₄ is deuterium labeled Nifurtimox. Nifurtimox, an antiprotozoal agent, which is generally used for the treatment of infections with Trypanosoma cruzi, has been used in the therapy of neuroblastoma. Nifurtimox affects enzyme activity of lactate dehydrogenase (LDH).

HY-136440S1

Hydroxymetronidazole-d2
Hydroxymetronidazole-d2 is the deuterium labeled Hydroxymetronidazole(HY-136440).Hydroxymetronidazole (Metronidazole-OH) is a metabolite of Metronidazole belonging to the class of nitroimidazoles. Hydroxymetronidazole can be used for the research of certain bacterial and *protozoal* diseases in poultry, swine dysentery and genital trichomoniasis in cattle .

HY-B0565S

Ronidazole-d3
Ronidazole-d₃ is the deuterium labeled Ronidazole (HY-B0565) . Ronidazole is a potent and orally active *antiprotozoal* and anti-microbial agent. Ronidazole acts as a veterinary agent against Tritrichomonas foetus?in cats models. Ronidazole can be used the research of forhistomoniasis?and?swine?dysentery .

HY-B0688S3

Dapsone-15N2

Dapsone- ¹⁵N₂ (4,4′-Diaminodiphenyl sulfone- ¹⁵N₂) is ¹⁵N labeled Dapsone. Dapsone (4,4′-Diaminodiphenyl sulfone) is an orally active and blood-brain penetrant sulfonamide antibiotic with bacteriostatic, antimycobacterial and antiprotozoal activities . Dapsone?exerts effective antileprosy activity?and inhibits folate synthesis in cell extracts of?M. leprae. Dapsone is used for dermatologic disorder research, including leprosy, dermatitis herpetiformis, acne vulgaris et al .

HY-B0740S3

Cyclobenzaprine-d3-1 hydrochloride

Cyclobenzaprine-d3-1 hydrochloride (MK130-d3-1 hydrochloride) is the deuterium labeled Cyclobenzaprine hydrochloride (HY-B0740). Cyclobenzaprine (MK130) hydrochloride is an orally active 5-HT₂ receptor antagonist. Cyclobenzaprine hydrochloride acts centrally, providing skeletal muscle relaxation, alleviating muscle spasms, and reducing pain. Additionally, Cyclobenzaprine hydrochloride has antiprotozoal activity. Additionally, Cyclobenzaprine hydrochloride also possesses antiparasitic activity. Cyclobenzaprine hydrochloride holds promise for research in the fields of acute, painful skeletal muscle disorders and infectious diseases

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