14113-05-4
14113-05-4
Chemical Structure
Royal Jelly acid
Synonym(s): (E)-Queen Bee Acid;(E)-10-Hydroxy-2-decenoic acid
- CAS No.: 14113-05-4
- Formula:C10H18O3
- Molecular Weight:186.25
IUPAC Name: (E)-10-hydroxydec-2-enoic acid
InChIKey: QHBZHVUGQROELI-SOFGYWHQSA-N
SMILES: O=C(O)/C=C/CCCCCCCO
Biological Activity: Royal Jelly Acid ((E)-Queen Bee Acid) is a major fatty acid found in royal jelly with oral bioavailability, exhibiting anti-inflammatory, anticancer, antimalarial, antiprotozoal, and neuroregulatory activities. Royal Jelly Acid can be used for research in various fields, including cancer, infections, immune inflammation, and neurological diseases[1][2][3][4][5][6][7].
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Royal Jelly acid | 99.95% | Royal Jelly Acid ((E)-Queen Bee Acid) is a major fatty acid found in royal jelly with oral bioavailability, exhibiting anti-inflammatory, anticancer, antimalarial, antiprotozoal, and neuroregulatory activities. Royal Jelly Acid can be used for research in various fields, including cancer, infections, immune inflammation, and neurological diseases. | ||||||||||||||||||||
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Royal Jelly acid (Standard) | ≥98% | Royal Jelly acid (Standard) is the analytical standard of Royal Jelly acid. This product is intended for research and analytical applications. Royal Jelly acid (Queen Bee Acid) is a fatty acid constituent of royal jelly, promotes the growth and protection of neurons, reduces anxiety-like phenotypes. | ||||||||||||||||||||
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References
- [1]. Weiser MJ, et al. Long-Term Administration of Queen Bee Acid (QBA) to Rodents Reduces Anxiety-Like Behavior, Promotes Neuronal Health and Improves Body Composition. Nutrients. 2017 Dec 23;10(1). [Content Brief]
- [2]. Sugiyama T, et al. Royal jelly acid, 10-hydroxy-trans-2-decenoic acid, as a modulator of the innate immune responses. Endocr Metab Immune Disord Drug Targets. 2012 Dec;12(4):368-76. [Content Brief]
- [3]. Sugiyama T, et al. Inhibitory mechanism of 10-hydroxy-trans-2-decenoic acid (royal jelly acid) against lipopolysaccharide- and interferon-β-induced nitric oxide production. Inflammation. 2013 Apr;36(2):372-8. [Content Brief]
- [4]. Ali A M, et al. The effects of royal jelly acid, 10-hydroxy-trans-2-decenoic acid, on neuroinflammation and oxidative stress in astrocytes stimulated with lipopolysaccharide and hydrogen peroxide[J]. Immuno, 2021, 1(3): 212-222.
- [5]. Alkhaibari AM, et al. Insecticidal, Antimalarial, and Antileishmanial Effects of Royal Jelly and Its Three Main Fatty Acids, trans-10-Hydroxy-2-decenoic Acid, 10-Hydroxydecanoic Acid, and Sebacic Acid. Evid Based Complement Alternat Med. 2022 Jan 20;2022:7425322. [Content Brief]
- [6]. Shahla J, et al. Comparative immunomodulatory effects of jelly royal and 10-H2DA on experimental autoimmune encephalomyelitis[J]. Gene Reports, 2021, 24: 101217.
- [7]. Jenkhetkan W, et al. Antiproliferative and cytotoxic efficacy of 10-hydroxy-2-decenoic acid, compared to doxorubicin, on MCF-7 breast cancer cells[J]. Trends in Sciences, 2021, 18(21): 409-409.
