3 Results for "

B and T cell lymphocyte attenuator

" in MedChemExpress (MCE) Product Catalog:
Products (3)

3 Results for "B and T cell lymphocyte attenuator" in MCE Product Catalog:

Cat. No.: HY-P99961
CAS No.: 2236068-83-8
Synonyms: JS004; Icatolimab

Target:  

CD28

Research Areas:  

Cancer

Tifcemalimab (JS004; Icatolimab) is a humanized IgG4 monoclonal antibody against BTLA (B and T lymphocyte attenuator). By binding to BTLA, tifcemalimab blocks the interaction of HVEM-BTLA, thereby inhibiting the BTLA-mediated inhibitory signaling pathway. Tifcemalimab can be used in research related to squamous cell non-small cell lung cancer .
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Cat. No.: HY-P10851
Target:  

Apoptosis

Research Areas:  

Inflammation/Immunology Cancer

HVEM(14-39) is a B- and T-lymphocyte attenuator (BTLA) peptide inhibitor. HVEM (14-39) can be combined with BTLA with a KD of 0.102 μM. HVEM(14-39) enhances the activation and proliferation of T cells by regulating the expression of BTLA and HVEM in T cells, and promotes the transformation of cells into effector memory T cells. HVEM(14-39) inhibits tumor cell proliferation and promotes late apoptosis. HVEM(14-39) has immunomodulatory effects and can be used in the study of cancer .
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Cat. No.: HY-P992182

Research Areas:  

Inflammation/Immunology

ANB032 is a human IgG4 kappa BTLA agonist monoclonal antibody. ANB032 inhibits activated T cell proliferation and reduces secretion of inflammatory cytokines. ANB032 can be used for the research of atopic dermatitis[1].
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