19 Results for "

CD98

" in MedChemExpress (MCE) Product Catalog:
Products (19)

19 Results for "CD98" in MCE Product Catalog:

Cat. No.: HY-P991669
Synonyms: AML-01

Target:  

Caspase Apoptosis

Research Areas:  

Cancer

IGN523 is an anti-CD98 antibody (hCD98, KD = 0.55 nM). IGN523 induces antibody-dependent cell-mediated cytotoxicity (ADCC) activity, lysosomal membrane permeabilization, and inhibition of essential amino acid transport, ultimately leading to caspase-3 and caspase-7-mediated apoptosis of tumor cells. IGN523 inhibits tumor growth in multiple tumor xenograft models. IGN523 is useful in the research of non-small cell lung cancer (NSCLC), acute myeloid leukemia (AML), and other cancers. .
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Cat. No.: HY-139664A
CAS No.: 2170140-50-6
Purity:  98.97%
Target:  

DNA Methyltransferase

Research Areas:  

Cancer

(R)-GSK-3685032 is the R-enantiomer of GSK-3685032 (HY-139664) and is a potent, non-covalent, reversible DNMT1-selective inhibitor with an IC50 of 0.036 μM against DNMT1. (R)-GSK-3685032 preferentially binds DNMT1 in a hemimethylated DNA context, inhibits DNA methylation maintenance by occupying the DNMT1 active site loop that inserts into DNA and by interacting with the target recognition domain, thereby inducing DNA hypomethylation and transcriptional activation. (R)-GSK-3685032 is useful for research on DNMT1, acute myeloid leukemia, and B cell humoral immunity .
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Cat. No.: HY-RS13331
Research Areas:  

Others

SLC7A5 Human Pre-designed siRNA Set A contains three designed siRNAs for SLC7A5 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS13242
Research Areas:  

Others

SLC3A2 Human Pre-designed siRNA Set A contains three designed siRNAs for SLC3A2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-P990610

Target:  

Akt mTOR PI3K

Research Areas:  

Cancer

KHK-2898 is a monoclonal antibody targeting CD98, which binds to the extracellular domain of CD98 on the tumor cell membrane in a non-covalent antigen-specific mode. KHK-2898 can disrupt the heterodimeric complex formed by CD98 with LAT1 and xCT light chains, reduce the amino acid uptake capacity of tumor cells, block the PI3K/AKT/mTOR proliferative signaling cascade, and mediate antibody-dependent cytotoxicity. KHK-2898 can be used for cancer-related research. The isotype control of KHK-2898 can be found in Human IgG1 kappa, Isotype Control (HY-P99001) .
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Cat. No.: HY-P810378
Synonyms: 4F2 LC, 4F2 light chain, 4F2LC, CD98, CD98 light chain, CD98LC, D16S469E, DC49, E16, hLAT1

Host:  

Rabbit

Application:  

WB, ICC/IF, IHC-P, IP

Reactivity:  

Human, Mouse, Rat

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Cat. No.: HY-P703725
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.;≥ 95%, as determined by HPLC.
Synonyms: SLC3A2; Solute Carrier Family 3 (Activators Of Dibasic And Neutral Amino Acid Transport), Member 2; Prev. MDU1; Solute Carrier Family 3 (Amino Acid Transporter Heavy Chain), Member 2; 4F2 Cell-Surface Antigen Heavy Chain; Monoclonal Antibody 44D7; Lymphoc
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P703724
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: SLC3A2; Solute Carrier Family 3 (Activators Of Dibasic And Neutral Amino Acid Transport), Member 2; Prev. MDU1; Solute Carrier Family 3 (Amino Acid Transporter Heavy Chain), Member 2; 4F2 Cell-Surface Antigen Heavy Chain; Monoclonal Antibody 44D7; Lymphoc
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P75367
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: SLC3A2; Solute Carrier Family 3 (Activators Of Dibasic And Neutral Amino Acid Transport), Member 2; Prev. MDU1; Solute Carrier Family 3 (Amino Acid Transporter Heavy Chain), Member 2; 4F2 Cell-Surface Antigen Heavy Chain; Monoclonal Antibody 44D7; Lymphoc
Species:  
Mouse
Source:  
HEK293
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Cat. No.: HY-P811712
Synonyms: CD98, MDU1, SLC3A2, Amino acid transporter heavy chain SLC3A2, 4F2 cell-surface antigen heavy chain, 4F2 heavy chain antigen, Lymphocyte activation antigen 4F2 large subunit, Solute carrier family 3 member 2, 4F2hc

Host:  

Rabbit

Application:  

WB, IHC-P, IP

Reactivity:  

Human

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Cat. No.: HY-P701272
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: SLC3A2; Solute Carrier Family 3 (Activators Of Dibasic And Neutral Amino Acid Transport), Member 2; Prev. MDU1; Solute Carrier Family 3 (Amino Acid Transporter Heavy Chain), Member 2; 4F2 Cell-Surface Antigen Heavy Chain; Monoclonal Antibody 44D7; Lymphoc
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P75368
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: SLC3A2; Solute Carrier Family 3 (Activators Of Dibasic And Neutral Amino Acid Transport), Member 2; Prev. MDU1; Solute Carrier Family 3 (Amino Acid Transporter Heavy Chain), Member 2; 4F2 Cell-Surface Antigen Heavy Chain; Monoclonal Antibody 44D7; Lymphoc
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P811712A
Synonyms: CD98, MDU1, SLC3A2, Amino acid transporter heavy chain SLC3A2, 4F2 cell-surface antigen heavy chain, 4F2 heavy chain antigen, Lymphocyte activation antigen 4F2 large subunit, Solute carrier family 3 member 2, 4F2hc

Host:  

Rabbit

Application:  

WB, IHC-P, IP

Reactivity:  

Human

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Cat. No.: HY-P75663
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: SLC3A2; Solute Carrier Family 3 (Activators Of Dibasic And Neutral Amino Acid Transport), Member 2; Prev. MDU1; Solute Carrier Family 3 (Amino Acid Transporter Heavy Chain), Member 2; 4F2 Cell-Surface Antigen Heavy Chain; Monoclonal Antibody 44D7; Lymphoc
Species:  
Rat
Source:  
HEK293
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Cat. No.: HY-P75664
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: SLC3A2; Solute Carrier Family 3 (Activators Of Dibasic And Neutral Amino Acid Transport), Member 2; Prev. MDU1; Solute Carrier Family 3 (Amino Acid Transporter Heavy Chain), Member 2; 4F2 Cell-Surface Antigen Heavy Chain; Monoclonal Antibody 44D7; Lymphoc
Species:  
Rat
Source:  
HEK293
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Cat. No.: HY-P81448
Synonyms: SLC7A5; CD98LC, LAT1; MPE16; Large neutral amino acids transporter small subunit 1; 4F2 light chain (4F2 LC; 4F2LC); CD98 light chain; Integral membrane protein E16; Solute carrier family 7 member 5

Host:  

Rabbit

Application:  

IHC-P

Reactivity:  

Human

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Cat. No.: HY-P81448A
Synonyms: SLC7A5; CD98LC, LAT1; MPE16; Large neutral amino acids transporter small subunit 1; 4F2 light chain (4F2 LC; 4F2LC); CD98 light chain; Integral membrane protein E16; Solute carrier family 7 member 5

Host:  

Rabbit

Application:  

IHC-P

Reactivity:  

Human

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Cat. No.: HY-P703726
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: SLC3A2; Solute Carrier Family 3 (Activators Of Dibasic And Neutral Amino Acid Transport), Member 2; Prev. MDU1; Solute Carrier Family 3 (Amino Acid Transporter Heavy Chain), Member 2; 4F2 Cell-Surface Antigen Heavy Chain; Monoclonal Antibody 44D7; Lymphoc
Species:  
Cynomolgus
Source:  
HEK293
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Cat. No.: HY-RS16997
Research Areas:  

Others

Slc3a2 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Slc3a2 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

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