CD98 Protein, Cynomolgus (HEK293, His)

CD98 Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived CD98 protein, expressed by HEK293, with N-His tag.

CD98, a multifunctional protein, is predicted to possess amino acid transmembrane transporter activity and double-stranded RNA binding activity. Its involvement in carboxylic acid transport and viral entry into host cells, as well as its role upstream of response to exogenous dsRNA, highlights its diverse functions. CD98 is strategically located in the apical pole of neurons and is actively engaged in synaptic processes. Its expression spans various structures, including the alimentary system, brain, genitourinary system, hemolymphoid system gland, and spinal cord. The ubiquity of CD98 expression is evident in numerous tissues, such as the kidney, genital fat pad, and 28 other tissues, underscoring its importance in various physiological contexts. Elucidating the intricate roles of CD98 in transport, cellular entry, and synaptic function is essential for comprehending its contributions to cellular processes and potential implications in health and disease.

Cynomolgus

HEK293

N-8*His

XP_045227941 (R175-A599)

Partial

RAPRCRELPAQKWWHTGALYRIGDLQAFQGHGSGNLAGLKGRLDYLSSLKVKGLVLGPLHKNQKDDVAQTDLLQIDPNFGSKEDFDSLLQSAKKKSIRVILDLTPNYRGENLWFSTQVDSVATKVKDALEFWLQAGVDGFQVRDIENLKDASSFLAEWENITKGFSEDRLLIAGTNSSDLQQIVSLLESNKDLLLTSSYLSDSSFTGEHTKSLVTQYLNATGNRWCSWSLSQAGLLTSFLPAQLLRLYQLMLFTLPGTPVFSYGDEIGLKAAALPGQPVEAPVMLWDESSFPDIPGAVSANMTVKGQSEDPGSLLSLFRQLSDQRSKERSLLHGDFHTFSSGPGLFSYIRHWDQNERFLVVLNFGDVGLSAGLQASDLPASASLPTKADLVLSTQPGREEGSPLELERLKLEPHEGLLLRFPYVA

Approximately 50-70 kDa,based on SDS-PAGE under reducing conditions,due to the glycosylation.

≥ 95%, as determined by reducing SDS-PAGE.

<1 EU/μg, determined by LAL method.