1 Result for "

CLL/SLL

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "CLL/SLL" in MCE Product Catalog:

Cat. No.: HY-175342
CAS No.: 2248046-39-9
Synonyms: LOXO-338
Target:  

Bcl-2 Family

Research Areas:  

Cancer

FCN-338 (LOXO-338) is an orally active and selective Bcl-2 inhibitor with an IC50 of 4.5 nM for Bcl-2/BAK interaction. FCN-338 potently inhibits tumor growth in follicular lymphoma (FL), acute myeloid leukemia (AML), and acute lymphoblastic leukemia (ALL) xenograft mice model without significant weight loss. FCN-338 has a broad-spectrum anti-cancer activity, such as FL, CLL/SLL, AML, and ALL .
loading...
    loading...