203 Results for "

Casein

" in MedChemExpress (MCE) Product Catalog:
Products (203)

203 Results for "Casein" in MCE Product Catalog:

1135
LY294002 hydrochloride
LY294002 hydrochloride
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1135 Publications Verification
Cat. No.: HY-10108A
CAS No.: 934389-88-5
Purity:  99.93%
Target:  

PI3K Casein Kinase DNA-PK Apoptosis

Research Areas:  

Cancer

LY294002 hydrochloride is a potent and broad-spectrum PI3K inhibitor, with IC50 values of 0.5, 0.57, and 0.97 μM for P110α, P110δ and P110β, respectively. LY294002 hydrochloride also inhibits CK2 with an IC50 of 98 nM. LY294002 hydrochloride can be used for pancreatic cancer research .
182
H-89
H-89
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182 Cited Publications
Cat. No.: HY-15979
CAS No.: 127243-85-0
Target:  

PKA Autophagy

Research Areas:  

Neurological Disease

H-89 is a potent and selective inhibitor of cyclic AMP-dependent protein kinase (protein kinase A) with IC50 of 48 nM and has weak inhibition on PKG, PKC, Casein Kinase, and others kinases.
182
H-89 dihydrochloride
H-89 dihydrochloride
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182 Cited Publications
Cat. No.: HY-15979A
CAS No.: 130964-39-5
Target:  

PKA Autophagy

Research Areas:  

Others

H-89 dihydrochloride is a potent and selective inhibitor of protein kinase A (PKA) with an IC50 of 48 nM and has weak inhibition on PKG, PKC, Casein Kinase.
59
Pepstatin
Pepstatin
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59 Cited Publications
Cat. No.: HY-P0018
CAS No.: 26305-03-3
Synonyms: Pepstatin A
Category:  

Natural Products Microorganisms Disease Research Fields Cancer

Target:  

HIV Protease Autophagy

Pepstatin (Pepstatin A) is a specific, orally active aspartic protease inhibitor produced by actinomycetes, with IC50s of 4.5 nM, 6.2 nM, 150 nM, 290 nM, 520 nM and 260 nM for hemoglobin-pepsin, hemoglobin-proctase, casein-pepsin, casein-proctase, casein-acid protease and hemoglobin-acid protease, respectively. Pepstatin also inhibits HIV protease .
59
Pepstatin Trifluoroacetate
Pepstatin Trifluoroacetate
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59 Cited Publications
Cat. No.: HY-P0018A
Synonyms: Pepstatin A Trifluoroacetate
Category:  

Infection Natural Products Microorganisms Disease Research Fields

Target:  

HIV Protease Autophagy

Pepstatin (Pepstatin A) Trifluoroacetate is a specific, orally active aspartic protease inhibitor produced by actinomycetes, with IC50s of 4.5 nM, 6.2 nM, 150 nM, 290 nM, 520 nM and 260 nM for hemoglobin-pepsin, hemoglobin-proctase, casein-pepsin, casein-proctase, casein-acid protease and hemoglobin-acid protease, respectively. Pepstatin Trifluoroacetate also inhibits HIV protease .
59
Pepstatin Ammonium
Pepstatin Ammonium
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59 Cited Publications
Cat. No.: HY-P0018B
Synonyms: Pepstatin A Ammonium
Category:  

Infection Natural Products Microorganisms Disease Research Fields

Target:  

HIV Protease Autophagy

Pepstatin (Pepstatin A) Ammonium is a specific, orally active aspartic protease inhibitor produced by actinomycetes, with IC50s of 4.5 nM, 6.2 nM, 150 nM, 290 nM, 520 nM and 260 nM for hemoglobin-pepsin, hemoglobin-proctase, casein-pepsin, casein-proctase, casein-acid protease and hemoglobin-acid protease, respectively. Pepstatin Ammonium also inhibits HIV protease .
39
Emodin
Emodin
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39 Cited Publications
Cat. No.: HY-14393
CAS No.: 518-82-1
Purity:  99.25%
Synonyms: Frangula emodin
Category:  

Polygonaceae Plants Endogenous metabolite Quinones Human Gut Microbiota Metabolites Microorganisms Rheum palmatum L. Anthraquinones Phenols Polyphenols Disease Research Fields Cancer

Target:  

SARS-CoV Casein Kinase Autophagy 11β-HSD

Emodin (Frangula emodin), an anthraquinone derivative, is an anti-SARS-CoV compound. Emodin blocks the SARS coronavirus spike protein and angiotensin-converting enzyme 2 (ACE2) interaction . Emodin inhibits casein kinase-2 (CK2). Anti-inflammatory and anticancer effects . Emodin is a potent selective 11β-HSD1 inhibitor with the IC50 of 186 and 86 nM for human and mouse 11β-HSD1, respectively. Emodin ameliorates metabolic disorder in diet-induced obese mice .
39
Emodin (Standard)
Emodin (Standard)
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39 Cited Publications
Cat. No.: HY-14393R
CAS No.: 518-82-1
Synonyms: Frangula emodin (Standard)
Category:  

Quinones Rheum palmatum L. Polygonaceae Phenols Plants Disease Research Fields Cancer

Target:  

Reference Standards SARS-CoV Casein Kinase Autophagy 11β-HSD

Emodin (Standard) is the analytical standard of Emodin. This product is intended for research and analytical applications. Emodin (Frangula emodin), an anthraquinone derivative, is an anti-SARS-CoV compound. Emodin blocks the SARS coronavirus spike protein and angiotensin-converting enzyme 2 (ACE2) interaction . Emodin inhibits casein kinase-2 (CK2). Anti-inflammatory and anticancer effects . Emodin is a potent selective 11β-HSD1 inhibitor with the IC50 of 186 and 86 nM for human and mouse 11β-HSD1, respectively. Emodin ameliorates metabolic disorder in diet-induced obese mice .
20
Trypsin, porcine pancreas (Cell culture grade)
Trypsin, porcine pancreas (Cell culture grade)
0 Images
20 Cited Publications
Cat. No.: HY-129047E
CAS No.: 9002-07-7
Target:  

Ser/Thr Protease

Research Areas:  

Others

Trypsin, porcine pancreas (Cell culture grade) is a serine protease that hydrolyzes proteins at the carboxyl side of lysine or arginine residues. Trypsin, porcine pancreas (Cell culture grade) exhibits excellent protein digestibility for α-lactalbumin and β-casein. Trypsin, porcine pancreas (Cell culture grade) removes cellular components while preserving extracellular matrix structures to achieve uniform decellularization of porcine pancreas .
15
TBB
TBB
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15 Cited Publications
Cat. No.: HY-14394
CAS No.: 17374-26-4
Purity:  98.54%
Synonyms: NSC 231634; Casein Kinase II Inhibitor I
Target:  

Casein Kinase

Research Areas:  

Cancer

TBB is a cell-permeable and ATP-competitive CK2 inhibitor with an IC50 of 0.15 μM for rat liver CK2.
13
D4476
D4476
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13 Cited Publications
Cat. No.: HY-10324
CAS No.: 301836-43-1
Purity:  99.94%
Synonyms: Casein Kinase I Inhibitor
Target:  

Casein Kinase Autophagy Apoptosis

Research Areas:  

Cancer

D4476 is a potent, selective and cell-permeable inhibitor of casein kinase 1(CK1) with an IC50 value of 0.3 μM in vitro.
12
TAK-715
TAK-715
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12 Cited Publications
Cat. No.: HY-10456
CAS No.: 303162-79-0
Purity:  99.76%
Target:  

p38 MAPK Casein Kinase Wnt

Research Areas:  

Inflammation/Immunology

TAK-715 is an orally active and potent p38 MAPK inhibitor with IC50s of 7.1 nM, 200 nM for p38α and p38β, respectively. TAK-715 inhibits casein kinase I (CK1δ/ε) to regulate activation of Wnt/β-catenin signaling. TAK-715 shows good significant efficacy in a rat arthritis model .
9
DMAT
DMAT
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9 Cited Publications
Cat. No.: HY-15535
CAS No.: 749234-11-5
Purity:  98.09%
Synonyms: CK2 Inhibitor; Casein kinase II Inhibitor
Target:  

Casein Kinase

Research Areas:  

Cancer

DMAT is a potent and specific CK2 inhibitor with an IC50 value of 130 nM.
9
5,6-Dichlorobenzimidazole riboside
5,6-Dichlorobenzimidazole riboside
0 Images
9 Cited Publications
Cat. No.: HY-14392
CAS No.: 53-85-0
Purity:  99.89%
Synonyms: DRB
Target:  

CDK Apoptosis

Research Areas:  

Cancer

5,6-Dichlorobenzimidazole riboside (DRB) is a nucleoside analog that inhibits several carboxyl-terminal domain kinases, including casein kinase II and cell cycle-dependent kinases (CDK). 5, 6-dichlorobenzimidazole riboside has antitumor activity. 5, 6-dichlorobenzimidazole riboside can induce apoptosis .
8
PF-670462 dihydrochloride
PF-670462 dihydrochloride
0 Images
8 Cited Publications
Cat. No.: HY-15490
CAS No.: 950912-80-8
Purity:  99.96%
Target:  

Casein Kinase

Research Areas:  

Cancer

PF-670462 dihydrochloride is a potent and selective inhibitor of casein kinase (CK1ε and CK1δ), with IC50s of 7.7 nM and 14 nM, respectively.
5
Umbralisib
Umbralisib
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5 Cited Publications
Cat. No.: HY-12279
CAS No.: 1532533-67-7
Purity:  98.94%
Synonyms: TGR-1202; RP5264
Target:  

PI3K Casein Kinase

Research Areas:  

Cancer

Umbralisib (TGR-1202) is an orally active, potent and selective dual PI3Kδ and casein kinase-1-ε (CK1ε) inhibitor, with EC50 of 22.2 nM and 6.0 μM, respectively. Umbralisib exhibits unique immunomodulatory effects on chronic lymphocytic leukemia (CLL) T cells. Umbralisib can be used for haematological malignancies reseach .
5
Umbralisib hydrochloride
Umbralisib hydrochloride
0 Images
5 Cited Publications
Cat. No.: HY-12279C
CAS No.: 1532533-78-0
Purity:  99.04%
Synonyms: TGR-1202 hydrochloride; RP5264 hydrochloride
Target:  

PI3K Casein Kinase

Research Areas:  

Cancer

Umbralisib (TGR-1202) hydrochloride is an orally active, potent and selective dual PI3Kδ and casein kinase-1-ε (CK1ε) inhibitor, with EC50 of 22.2 nM and 6.0 μM, respectively. Umbralisib hydrochloride exhibits unique immunomodulatory effects on chronic lymphocytic leukemia (CLL) T cells. Umbralisib hydrochloride can be used for haematological malignancies reseach .
3
WL47 TFA
WL47 TFA
0 Images
3 Cited Publications
Cat. No.: HY-P2288A
Target:  

Peptides

Research Areas:  

Cancer

WL47 TFA, a high-affinity cavolin-1 (CAV1) ligand (Kd=23 nM), is a potent disrupter of CAV1 oligomers. WL47 TFA shows selectivity for CAV1 over BSA, casein and HEWL. WL47 TFA is 80% smaller in length than the original T20 (HY-P0052) parent sequence and can be used for the study of caveolin-1 function .
2
Casein
Casein
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2 Cited Publications
Cat. No.: HY-125865
CAS No.: 9000-71-9
Purity:  97.40%
Casein is an orally active phosphoprotein that can be separated into various electrophoretic components, such as α2-Casein, κ-Casein, β-casein, and γ-casein. Casein has also been blended and grafted with other polymers, cross-linkers, or monomers to improve its functional properties. Casein enhances calcium absorption and reduces the extent of fissure as well as smooth-surface caries. Casein promotes proliferation of prostate cancer. Casein has various applications in the paper, leather, textile, and food industries, serving as coatings, adhesives, and packaging materials .
2
Casein Kinase 2 Substrate Peptide
Casein Kinase 2 Substrate Peptide
0 Images
2 Cited Publications
Cat. No.: HY-P3815
CAS No.: 132176-35-3
Target:  

Casein Kinase

Research Areas:  

Others

Casein Kinase 2 Substrate Peptide is a common CK2 substrate peptide. Casein Kinase 2 Substrate Peptide is synthesized with its C-terminus conjugated to 5-[(2-aminoethyl)amino]naphthalene-1-sulfonic acid (EDANS). Casein Kinase 2 Substrate Peptide can be used for protein kinase CK2 activity determination .
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