20 Results for "

Cephalosporin C

" in MedChemExpress (MCE) Product Catalog:
Products (20)

20 Results for "Cephalosporin C" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-B1299
CAS No.: 61-24-5
Target:  

Bacterial

Research Areas:  

Infection

Cephalosporin C has weak resistance to Gram-positive and negative bacteria, is stable to penicillinase, and can be broken down by cephalosporin enzyme. Hydrolysis and removal of side chains to obtain 7-amino-cefenoic acid (7-ACA) is an important raw material for the preparation of semi-synthetic cephalosporin .
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5
5 Cited Publications
Cat. No.: HY-B1275
CAS No.: 58-71-9
Synonyms: Cefalotin sodium
Research Areas:  

Infection

Cephalothin (Cephalotin) sodium is a semi-synthetic cephalosporin antibiotic and beta-lactam antibiotic. Cephalothin inhibits class C β-lactamase AmpC, with an Ki of 0.32 µM. Cephalothin sodium binds to penicillin-binding proteins, interfering with the cross-linking of peptidoglycan in the cell wall and thus hindering the normal synthesis of the bacterial cell wall. Cephalothin sodium shows antibacterial activity against a variety of bacteria. Cephalothin sodium can be used in hematological and nephrotoxicity studies .
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5
5 Cited Publications
Cat. No.: HY-B1275A
CAS No.: 153-61-7
Synonyms: Cephalotin
Cephalothin (Cephalotin) is a semi-synthetic cephalosporin antibiotic and beta-lactam antibiotic. Cephalothin inhibits class C β-lactamase AmpC, with an Ki of 0.32 µM. Cephalothin binds to penicillin-binding proteins, interfering with the cross-linking of peptidoglycan in the cell wall and thus hindering the normal synthesis of the bacterial cell wall. Cephalothin shows antibacterial activity against a variety of bacteria. Cephalothin can be used in hematological and nephrotoxicity studies .
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1
1 Cited Publications
Cat. No.: HY-B1299A
CAS No.: 59143-60-1
Cephalosporin C zinc salt is a potent inhibitor of SAMHD1 with an IC50 of 1.1 μM . Cephalosporin C zinc salt also has moderate anti-orthopoxvirus activity .
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Cat. No.: HY-B1892S1
CAS No.: 2101505-58-0
Synonyms: Cephazolin-13C2,15N
Cefazolin- 13C2, 15N (Cephazolin- 13C2, 15N) is 13C and 15N labeled Cefazolin. Cefazolin (Cephazolin) is a first-generation cephalosporin antibiotic and can be used in varieties of bacterial infections research . Cefazolin has anti-inflammatory effect and can attenuate post-operative cognitive dysfunction (POCD) .
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Cat. No.: HY-E70137
Target:  

Drug Intermediate

Research Areas:  

Others

AMG 118 Immobilized cephalosporin C acylase is an enzyme that catalyzes in immobilized form and is generally used in industrial catalytic production of the important pharmaceutical intermediate 7-aminocephalosporanic acid (7-ACA). It contains CPC acylase, a highly specialized beta-lactam acylase or peptidase that cleaves the amide bonds between beta-lactams .
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Cat. No.: HY-177567
CAS No.: 30361-42-3
Target:  

Bacterial

Research Areas:  

Infection

Cephalosporin C analog-1 is an analogue of Cephalosporin C (HY-B1299). Cephalosporin C has weak resistance to Gram-positive and negative bacteria, is stable to penicillinase, and can be broken down by cephalosporin enzyme. Hydrolysis and removal of side chains to obtain 7-amino-cefenoic acid (7-ACA) is an important raw material for the preparation of semi-synthetic cephalosporin .
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Cat. No.: HY-W654098
CAS No.: 1346602-30-9
Cefazolin- 13C2, 15N (sodium) is 13C and 15N labeled Cefazolin (sodium). Cefazolin sodium is a first-generation cephalosporin antibiotic and can be used in varieties of bacterial infections research . Cefazolin sodium has anti-inflammatory effect and can attenuate post-operative cognitive dysfunction (POCD).
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Cat. No.: HY-155011
CAS No.: 2832966-95-5
Target:  

Bacterial

Research Areas:  

Infection

MB076 is a novel heterocyclic triazole with improved plasma stability. MB076 inhibits seven different Class C Acinetobacter-derived cephalosporinases (ADCs) β-lactamase variants with Ki values <1 μM. MB076 acts synergistically in combination with multiple cephalosporins to restore pBCSK(-) susceptibility .
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Cat. No.: HY-B0712S1
Synonyms: Ro 13-9904-13C2,d32 triethylammonium salt
Ceftriaxone-13C2,d3 triethylammonium salt is 13C and deuterated labeled Ceftriaxone (HY-B0712). Ceftriaxone (Ro 13-9904 free acid) is a broad spectrum β-lactam third-generation cephalosporin antibiotic, which has good antibacterial activity against a variety of gram-negative and positive bacteria. Ceftriaxone is a covalent inhibitor of GSK3β with IC50 value of 0.78 mM. Ceftriaxone is an inhibitor of Aurora B. Ceftriaxone has anti-inflammatory, antitumor and antioxidant activities. Ceftriaxone can be used in the study of bacterial infections and meningitis .
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Cat. No.: HY-177567A
CAS No.: 30361-43-4
Target:  

Bacterial

Research Areas:  

Infection

Cephalosporin C analog-1 sodium is an analogue of Cephalosporin C (HY-B1299). Cephalosporin C has weak resistance to Gram-positive and negative bacteria, is stable to penicillinase, and can be broken down by cephalosporin enzyme. Hydrolysis and removal of side chains to obtain 7-amino-cefenoic acid (7-ACA) is an important raw material for the preparation of semi-synthetic cephalosporin .
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Cat. No.: HY-W770956
Synonyms: SCE-963-15N2; Cefotiam Dihydrochloride-15N2
Cefotiam- 13C, 15N2 (SCE-963- 13C, 15N2) is the 13C- and 15N-labeled Cefotiam (HY-B0734). Cefotiam (SCE-963) is a parenteral cephalosporin antibiotic. Cefotiam has broad-spectrum activity against Gram-positive and Gram-negative bacteria .
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Cat. No.: HY-B0136S
Synonyms: FK-482-13C,15N2; CI-983-13C,15N2
Cefdinir- 13C, 15N2 (FK-482- 13C, 15N2) is 13C and 15N labeled Cefdinir. Cefdinir (FK-482) is a semi-synthetic, broad-spectrum antibiotic in the third generation of the cephalosporin class, which is proved to be effective for infections caused by several Gram-negative and Gram-positive bacteria. Cefdinir can be used for the research of common bacterial infections of the ear, sinus, throat, and skin .
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Cat. No.: HY-B1190S2
Synonyms: BL-S 578-13C6
Cefadroxil- 13C6 (BL-S 578- 13C6) is 13C labeled Cefadroxil (HY-B1190). Cefadroxil is an orally active broad-spectrum cephalosporin antibiotic. Cefadroxil inhibits bacterial cell wall synthesis and enhances the expression of glutamate transporter-1. Cefadroxil is dependent on the intestinal peptide transporter PepT1 for small intestinal absorption. Cefadroxil has inhibitory and bactericidal activity against a variety of Gram-positive and Gram-negative bacteria and has analgesic effects on neuropathic pain .
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Cat. No.: HY-B1275AR
CAS No.: 153-61-7
Synonyms: Cephalotin (Standard)
Cephalothin (Cephalotin) (Standard) is the analytical standard of Cephalothin (HY-B1275A). This product is intended for research and analytical applications. Cephalothin is a semi-synthetic cephalosporin antibiotic and beta-lactam antibiotic. Cephalothin inhibits class C β-lactamase AmpC, with an Ki of 0.32 µM. Cephalothin binds to penicillin-binding proteins, interfering with the cross-linking of peptidoglycan in the cell wall and thus hindering the normal synthesis of the bacterial cell wall. Cephalothin shows antibacterial activity against a variety of bacteria. Cephalothin can be used in hematological and nephrotoxicity studies .
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Cat. No.: HY-B1275R
CAS No.: 58-71-9
Synonyms: Cefalotin sodium (Standard)
Cephalothin (Cephalotin) sodium (Standard) is the analytical standard of Cephalothin sodium (HY-B1275). This product is intended for research and analytical applications. Cephalothin sodium is a semi-synthetic cephalosporin antibiotic and beta-lactam antibiotic. Cephalothin inhibits class C β-lactamase AmpC, with an Ki of 0.32 µM. Cephalothin sodium binds to penicillin-binding proteins, interfering with the cross-linking of peptidoglycan in the cell wall and thus hindering the normal synthesis of the bacterial cell wall. Cephalothin sodium shows antibacterial activity against a variety of bacteria. Cephalothin sodium can be used in hematological and nephrotoxicity studies .
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Cat. No.: HY-P701944
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: BSU03180; cah; EC:3.1.1.72; Acetylxylan esterase; EC:3.1.1.41; Cephalosporin-C deacetylase
Species:  
Others
Source:  
E. coli
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Cat. No.: HY-B1381S
Synonyms: FR-17027-13C,15N2 ; FK-027-13C,15N2 ; CL-284635-13C,15N2
Cefixime- 13C, 15N2 (FR-17027- 13C, 15N2) is the 13C- and 15N-labeled Cefixime (HY-B1381). Cefixime (FR-17027) is an orally active antibiotic and a third generation cephalosporin antibiotic, useful for the treatment of a number of bacterial infections.
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Cat. No.: HY-105049S
Synonyms: T-91825-13C,d3 TFA; PPI-0903M-13C,d3 TFA
Research Areas:  

Infection

Ceftaroline- 13C,d3 (T-91825- 13C,d3) TFA is the 13C- and deuterated-labeled Ceftaroline TFA. Ceftaroline, an N-phosphono-type cephalosporin, is the active form of TAK-599. Ceftaroline is active against both gram-positive and gram-negative bacteria.
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Cat. No.: HY-W923278
CAS No.: 73547-70-3
Synonyms: GR20263 dihydrochloride
Target:  

Antibiotic Bacterial

Research Areas:  

Infection

Ceftazidime (GR20263) dihydrochloride is a cephalosporin β-lactam antibiotic. Ceftazidime dihydrochloride exhibits activity against susceptible Enterobacteriaceae, multidrug-resistant Gram-negative bacteria, Pseudomonas aeruginosa, and bacteria producing Ambler class A, C, and some class D β-lactamases, but shows no activity against microorganisms producing metallo-β-lactamases. Ceftazidime dihydrochloride reduces bacterial loads in mouse models of splenic, hepatic, and thigh infections, but has low efficacy against ESBL- and KPC-producing Enterobacteriaceae. Ceftazidime dihydrochloride can be used in research related to complicated urinary tract infections, complicated intra-abdominal infections, hospital-acquired pneumonia, carbapenemase-producing Klebsiella pneumoniae infections, carbapenem-resistant Enterobacterales infections, and severe Gram-negative bacterial infections .
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