2. Ceftazidime dihydrochloride

Ceftazidime dihydrochloride  (Synonyms: GR20263 dihydrochloride)

Cat. No.: HY-W923278
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CAS No. : 73547-70-3

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42 Publications Citing Use of MCE Ceftazidime dihydrochloride

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In Vivo Efficacy Study

    Ceftazidime dihydrochloride purchased from MedChemExpress. Usage Cited in: Mol Syst Biol. 2025 Jun 30.  [Abstract]

    Growth and cadaverine production dynamics in E. coli treated with 20 µM of Ceftazidime. Treated cultures show a brief period where the optical density (Absorbance, 595 nm) increases, concurrent with a burst of cadaverine production far above untreated levels. This indicates that this β-lactam antibiotic does not immediately kill the cells but allows for a brief period of growth and stress-induced polyamine production prior to bacterial cell lysis. Lines indicate the mean, and shaded areas the standard deviation of n = 6 biological replicates.

    Ceftazidime dihydrochloride purchased from MedChemExpress. Usage Cited in: AMB Express. 2024 Dec 24;14(1):141.  [Abstract]

    Combinational antimicrobial effects between PVB and conventional antibiotics against MRSA ATCC 43,300. TET, Tetracycline. DOX, Doxycycline. E, Erythromycin. AZI, Azithromycin. P, Penicillin. CAZ, Ceftazidime. AMP, Ampicillin. CEZ, Cefazolin. CEF, Cefotaxime. OXA, Oxacillin. CRO, Ceftriaxone. AMK, Amikacin. GEN, Gentamycin, KANA, Kanamycin. TOB, Tobramycin. SPC, Spectinomycin.

    Ceftazidime dihydrochloride purchased from MedChemExpress. Usage Cited in: Microorganisms. 2024 Mar 13;12(3):575.  [Abstract]

    Percentages of E. coli strains showing antimicrobial resistance to different antimicrobial agents. AMP, Ampicillin; CAZ, Ceftazidime; IPM, Imipenem; MRP, Meropenem; GEN, Gentamicin; OFX, Ofloxacin; SXT, Trimethoprim–sulfamethoxazole; TET, Tetracycline; TGC, Tigecycline; CL, Colistin; FFC, Florfenicol.

    Ceftazidime dihydrochloride purchased from MedChemExpress. Usage Cited in: J Antimicrob Chemother. 2022 Sep 30;77(10):2803-2808.  [Abstract]

    In vivo change in log10 cfu/thigh of each isolate treated with saline control, Ceftazidime 2 g IV q8h 2 h infusion HSR, Ceftazidime/Avibactam 2.5 g q8h 2 h infusion HSR or meropenem 2 g q8h 3 h infusion HSR for three P. aeruginosa with inserted GES β-lactamases. (a) PSA 2136, with inserted GES-1 (ESBL). (b) PSA 2137, with inserted GES-5 (carbapenemase). (c) PSA 2138, with inserted GES-15. P values in the boxes represent the results from one-way ANOVA; P values are presented if between-group differences were present. The x-axis describes the treatment HSR [MIC (mg/L), % fT>MIC]. CAZ, Ceftazidime; CAZ-AVI, Ceftazidime/Avibactam; MEM, meropenem.

    Ceftazidime dihydrochloride purchased from MedChemExpress. Usage Cited in: J Antimicrob Chemother. 2020 Jul 1;75(7):1850-1858.  [Abstract]

    The cumulative MIC distributions of Cefepime/Taniborbactam, Ceftazidime/Avibactam and comparator Meropenem for 500 tested isolates. The MICs of cefepime and Cefepime/Taniborbactam shown in the figure were tested by the broth microdilution method. The MICs of Meropenem shown in the figure were tested by the agar dilution method. SS, susceptible to all tested β-lactams. SS-P. aeruginosa, meropenem-susceptible P. aeruginosa. Nine IMP producers included three blaIMP-producing P. aeruginosa.

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    Molecular Weight

    619.50

    Formula

    C22H24Cl2N6O7S2
    CAS No.
    SMILES

    [O-]C(C1=C(C[N+]2=CC=CC=C2)CS[C@@]([C@@H]3NC(/C(C4=CSC(N)=N4)=N\OC(C)(C)C(O)=O)=O)([H])N1C3=O)=O.Cl.Cl
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      Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

    Keywords:

    Ceftazidime73547-70-3GR20263GR 20263GR-20263Inhibitorinhibitorinhibit

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