Ceftaroline-13C,d3 TFA
Ceftaroline-13C,d3 (T-91825-13C,d3) TFA is the 13C- and deuterated-labeled Ceftaroline TFA. Ceftaroline, an N-phosphono-type cephalosporin, is the active form of TAK-599. Ceftaroline is active against both gram-positive and gram-negative bacteria.
For research use only. We do not sell to patients.
- Formula: C2513CH19D3F6N8O9S4
- Molecular Weight:836.76
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Protocols
- Purity & Documentation
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Help & FAQs
Biological Activity
Description
In Vitro
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Further protocols information, click here.
Application
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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Molecular Weight 836.76
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Formula C2513CH19D3F6N8O9S4
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SMILES
OC(C(F)(F)F)=O.O=C1[C@@H](NC(/C(C2=NSC(N)=N2)=N\OCC)=O)[C@@]3([H])SCC(SC4=NC(C5=CC=[N+]([13C]([2H])([2H])[2H])C=C5)=CS4)=C(C([O-])=O)N13.OC(C(F)(F)F)=O
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Synonyms
T-91825-13C,d3 TFA; PPI-0903M-13C,d3 TFA
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Gram Staining of Tissue Sections
Gram staining of tissue sections is a histochemical technique used to differentiate Gram-positive and Gram-negative bacteria within histological specimens based on differences in bacterial cell wall structure and dye retention, adapted from classical bacteriological Gram staining into tissue-compatible “histological Gram stain” variants. In tissue applications, modifications of the Brown-Hopps and Brown-Brenn methods are commonly used to improve differentiation of microorganisms embedded within host connective tissue and to reduce overstaining or loss of Gram-negative signal, which are known limitations of earlier approaches. The principle relies on crystal violet-iodine complex retention in Gram-positive organisms and subsequent decolorization and counterstaining steps that allow contrast visualization of Gram-negative organisms against tissue background.
Purity & Documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Ceftaroline-13C,d3 TFA Related Classifications
HY-105049S Related Classifications
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