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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
16 Results for "
D-Mannosamine
" in MedChemExpress (MCE) Product Catalog:
Products (16)
16 Results for "D-Mannosamine" in MCE Product Catalog:
1
1 Cited Publications
Cat. No.: HY-W021425
CAS No.: 5505-63-5
Synonyms: (2S,3R,4S,5R)-2-Amino-3,4,5,6-tetrahydroxyhexanal hydrochloride
Target:
Category:
Human Gut Microbiota Metabolites Natural Products Neurological Disease Endogenous metabolite Disease Research Fields
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Cat. No.: HY-W040154
CAS No.: 7772-94-3
Synonyms: Cyclic ManNAc
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Cat. No.: HY-128850S1
CAS No.: 875654-27-6
Synonyms: N-AcetylMannosamine-13C; ManNAc-13C
Research Areas:
N-Acetylneuraminate lyase (CgNal) (Sialic acid aldolase (CgNal)) is a rate-limiting enzyme in bacteria metabolism that catalyzes the reversible aldol cleavage of sialic acid, and it regulates the overall metabolism of the bacterial sialic acid catabolic pathway. N-Acetylneuraminate lyase (CgNal) catalyzes the reversible condensation reaction of pyruvate and N-acetyl-d-mannosamine (ManNAc) to produce sialic acid N-acetylneuraminic acid (Neu5Ac). The protein expression of N-Acetylneuraminate lyase is downregulated at the translational level under the regulation of methyl methanesulfonate, and this change significantly impairs the adhesion and invasion abilities of bacteria to eukaryotic cells. N-Acetylneuraminate lyase is a key virulence-related protein in various pathogenic bacteria and is considered an antibiotic drug target. N-Acetylneuraminate lyase (CgNal) can be used in studies of invasive (extraintestinal) infectious diseases, Crohn's disease, and methicillin-resistant Staphylococcus aureus infections .
Cat. No.: HY-W040154R
CAS No.: 7772-94-3
Synonyms: Cyclic ManNAc (Standard)
Category:
Cat. No.: HY-128850S5
Synonyms: N-AcetylMannosamine-15N; ManNAc-15N
Cat. No.: HY-W021425R
CAS No.: 5505-63-5
Synonyms: (2S,3R,4S,5R)-2-Amino-3,4,5,6-tetrahydroxyhexanal hydrochloride (Standard)
Category:
Target:
Cat. No.: HY-W021425S1
Synonyms: (2S,3R,4S,5R)-2-Amino-3,4,5,6-tetrahydroxyhexanal-d2 hydrochloride
Cat. No.: HY-128850R
CAS No.: 3615-17-6
Synonyms: N-AcetylMannosamine (Standard); ManNAc (Standard)
Cat. No.: HY-128850S2
Synonyms: N-AcetylMannosamine-13C-1; ManNAc-13C-1
Cat. No.: HY-E70621
Research Areas:
Sialic acid aldolase (Pm NaNa) (EC 4.1.3.3) is a type I aldolase that catalyze the reversible aldol cleavage of N-acetylneuraminic acid (Neu5Ac) to form pyruvate and N-acetyl-D-mannosamine (ManNAc) with the equilibrium favoring the Neu5Ac cleavage .
Cat. No.: HY-W709216
CAS No.: 376645-66-8
Research Areas:
N-Acetyl-D-mannosamine-d3-1 is the deuterated-labeled N-Acetyl-D-mannosamine (HY-128850). N-Acetyl-D-mannosamine (ManNAc) is an oral active sialic acid precursor that can prevent hypertension by increasing sialylation of IgG, making it a promising candidate for cardiovascular disease research. Additionally, N-Acetyl-D-mannosamine can activate hypocretin (HCRT) gene expression in orexin neurons and improve neurodegeneration caused by aging, offering potential avenues for research in neurological disorders .
Cat. No.: HY-E71009
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Research Areas:
N-Acylmannosamine 1-Dehydrogenase, Pseudomonas sp. (EC 1.1.1.233) acts on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The two substrates of this enzyme are N-acyl-D-mannosamine and NAD+, whereas its 3 products are N-acyl-D-mannosaminolactone, NADH, and H+.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
